Results 21 to 30 of about 1,280,222 (240)
Study the Role of Cell Free DNA in the Diagnosis of Hepatocellular Carcinoma, an Egyptian Study
Asian Pacific Journal of Cancer Biology, 2022 Background and objective: Hepatocellular carcinoma (HCC) is a primary malignancy of the liver. Since the conventional tissue biopsy and AFP have limited value, a new promising diagnostic method” liquid biopsy” has emerged.
Noha Hassan Radwan +3 more
doaj +1 more source
Circulating biomarkers to monitor cancer progression and treatment
Computational and Structural Biotechnology Journal, 2016 Tumor heterogeneity is a major challenge and the root cause of resistance to treatment. Still, the standard diagnostic approach relies on the analysis of a single tumor sample from a local or metastatic site that is obtained at a given time point. Due to
Suthee Rapisuwon +2 more
doaj +1 more source
Clinical Chemistry, 2012 In 1947, Mandel and Metais discovered the unusual phenomenon of circulating cell-free DNA (1). Although one might naively think that DNA is found only in the nuclei of cells, it turns out that a substantial amount of small DNA fragments circulates within the blood.
openaire +2 more sources
In silico Design of Linear DNA for Robust Cell-Free Gene Expression
Frontiers in Bioengineering and Biotechnology, 2021 Cell-free gene expression systems with linear DNA expression templates (LDETs) have been widely applied in artificial cells, biochips, and high-throughput screening.
Xinjie Chen, Yuan Lu
doaj +1 more source
Tumor Biology, 2017 Head and neck squamous cell carcinoma is the most commonly diagnosed cancer worldwide. The lifestyle, food habits, and customary practices manifest the Northeast Indian population toward higher susceptibility to develop head and neck squamous cell ...
Manish Kumar +7 more
doaj +1 more source
University of Western Ontario Medical Journal, 2020 Chromosomal disorders arise from errors in cell division and many are detected during prenatal development. Prenatal genomic screening techniques involve invasive methods such as chorionic villus sampling and amniocentesis. In this feature, current invasive techniques for genetic screening will be examined in relation to the development of non-invasive
openaire +2 more sources
Comparison of methods for the quantification of cell-free DNA isolated from cell culture supernatant
Tumor Biology, 2019 Gaining a better understanding of the biological properties of cell-free DNA constitutes an important step in the development of clinically meaningful cell-free DNA–based tests.
Abel Jacobus Bronkhorst +2 more
doaj +1 more source
Cancer Detection from Plasma Cell-Free DNA [PDF]
E3S Web of Conferences, 2020 Liquid biopsy of cell-free DNA (cfDNA) has attracted much attention for its promise to realize pan-cancer detection in a non-invasive way. The whole-genome bisulfite sequencing (WGBS) is widely used in cfDNA sequencing analysis and lays the foundation ...
Chen Li
doaj +1 more source
Plasma Cell-Free DNA in Paediatric Lymphomas [PDF]
Journal of Cancer, 2013 Extracellular circulating DNA (cfDNA) can be found in small amounts in plasma of healthy individuals. Increased levels of cfDNA have been reported in patients with cancer of breast, cervix, colon, liver and it was shown that cfDNA can originate from both tumour and non-tumour cells.Levels of cfDNA of a large series of children with lymphoma were ...
MUSSOLIN, LARA +7 more
openaire +3 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source