Hyperactive sperm motility is important for successful fertilization. In the present study, a proteome profiling approach was performed to identify the differences between Landrace boars with different levels of hyperactive sperm motility in liquid ...
Maren van Son +7 more
doaj +1 more source
How to halve ploidy : lessons from budding yeast meiosis [PDF]
Maintenance of ploidy in sexually reproducing organisms requires a specialized form of cell division called meiosis that generates genetically diverse haploid gametes from diploid germ cells.
Arumugam, Prakash +2 more
core +1 more source
Therapeutic Potential of the Hsp90/Cdc37 Interaction in Neurodegenerative Diseases
Alzheimer’s, Huntington’s, and Parkinson’s are devastating neurodegenerative diseases that are prevalent in the aging population. Patient care costs continue to rise each year, because there is currently no cure or disease modifying treatments for these ...
Liam Gracia +3 more
doaj +1 more source
Inflammatory responses in primary muscle cell cultures in Atlantic salmon (Salmo salar) [PDF]
Peer reviewedPublisher ...
Martin, Samuel A.M. +3 more
core +2 more sources
Hsp90 modulates human sperm capacitation via the Erk1/2 and p38 MAPK signaling pathways
Background Heat shock protein 90 (Hsp90) is a highly abundant eukaryotic molecular chaperone that plays important roles in client protein maturation, protein folding and degradation, and signal transduction.
Peibei Sun +6 more
doaj +1 more source
Transcriptomic signatures of neuronal differentiation and their association with risk genes for autism spectrum and related neuropsychiatric disorders. [PDF]
Genes for autism spectrum disorders (ASDs) are also implicated in fragile X syndrome (FXS), intellectual disabilities (ID) or schizophrenia (SCZ), and converge on neuronal function and differentiation. The SH-SY5Y neuroblastoma cell line, the most widely
Chiocchetti, AG +10 more
core +1 more source
Objective To observe the expression profile of epidermal growth factor receptor (EGFR) during the differentiation of osteoclasts, and to explore EGFR-related signaling pathways and key genes during the process.
TAN Xin, ZHANG Ziyuan, LIU Xing
doaj +1 more source
3D structure prediction of replication factor C subunits (RFC) and their interactome in Arabidopsis thaliana [PDF]
DNA stress can causes potentially spontaneous genome damage during DNA replication process. Proteins involved in this process are DNA-dependent ATPases, required for replication and repair.
Mohamed Ragab Abdel Gawwad +2 more
doaj
The contribution of age structure to cell population responses to targeted therapeutics [PDF]
Cells grown in culture act as a model system for analyzing the effects of anticancer compounds, which may affect cell behavior in a cell cycle position-dependent manner.
Ackleh +52 more
core +7 more sources
Isolation of Yeast DNA Replication Mutants in Permeabilized Cells [PDF]
A random population of temperature-sensitive mutants was screened by assaying for defects in DNA synthesis in a permeabilized yeast DNA replication system. Twenty mutants defective in in vitro DNA synthesis have been isolated.
Campbell, Judith L. +2 more
core

