Results 191 to 200 of about 729,910 (357)

Constructing the spatiotemporal atlas of single-cell lineage trajectories in stereotypic biological structures. [PDF]

iScience
Wang R, Yang X, Lian C, Wang J, Chen J, Qian Y, Xu Y, Wang L, Marioni JC, Tam PPL, Jing N.   +10 more
europepmc   +1 more source

Correction to: Genetic Lineage Tracing of Sca-1 ⁺ Cells Reveals Endothelial but Not Myogenic Contribution to the Murine Heart [PDF]

, 2018

openalex   +1 more source

Bone Healing Around Implants in Normal and Medically Compromised Conditions: Osteoporosis and Diabetes

Advanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello, Fabio Variola, Antonio Nanci   +2 more
wiley   +1 more source

ICSH Recommendations for Monocyte Cell Lineage Morphologic Identification, Nomenclature Harmonization, and Utilization as a Biomarker. [PDF]

Int J Lab Hematol
Zini G, Chang YH, d'Onofrio G, Frater J, Germing U, Merino A, Pozdnyakova O, Ross D, Filho CRS, Takami A, Wendy E.   +10 more
europepmc   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Differential Hes1 activation defines neural stem cell lineage commitment and niche maintenance in embryonic and adult mouse cortex. [PDF]

Proc Natl Acad Sci U S A
Riya PA, Jose R, Meera V, Basu B, Surya S, Aryasree R, Jyothi NP, Parvathy S, Dhanesh SB, Sanalkumar R, Praz V, Riggi N, James J.   +12 more
europepmc   +1 more source

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source

Trilaciclib (T) decreases multi-lineage myelosuppression in extensive-stage small cell lung cancer (ES-SCLC) patients receiving first-line chemotherapy

, 2018
Konstantin H. Dragnev, Taofeek K. Owonikoko, Tibor Csőszi, Marina Maglakelidze, J. Thaddeus Beck, M. Dómine Gómez, Anna Łowczak, András Fülöp, Robert J. Hoyer, Wahid T. Hanna, Philip Lowry, Raid Aljumaily, V.K. Chiu, Iurie Bulat, Yang Zhao, Pamela Roberts, J.M. Antal, Rajesh Malik, Shannon R. Morris, J. Weiß   +19 more
openalex   +1 more source

Synergy between the pre–T cell receptor and Notch: cementing the αβ lineage choice [PDF]

, 2006
Cynthia J. Guidos
openalex   +1 more source

A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis

Advanced Healthcare Materials, EarlyView.
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra, Fleur R. Semmekrot, Nuno Araújo‐Gomes, Daniël Wijnperle, Monique M. A. Helsen, Martijn H.J. Van Den Bosch, Loes. I. Segerink, Séverine Le Gac, Marcel Karperien   +8 more
wiley   +1 more source