Results 301 to 310 of about 11,198,861 (420)

Optimization of the Irf8 +32-kb enhancer disrupts dendritic cell lineage segregation. [PDF]

Nat Immunol
Ou F, Liu TT, Desai P, Ferris ST, Kim S, Shen H, Ohara RA, Jo S, Chen J, Postoak JL, Du S, Diamond MS, Murphy TL, Murphy KM.   +13 more
europepmc   +1 more source

Cell cycle-dependent initiation and lineage-dependent abrogation of GATA-1 expression in pure differentiating hematopoietic progenitors.

, 1992
N M Sposi, L I Zon, Alessandra Carè, M Valtieri, Ugo Testa, Marco Gabbianelli, Giuliano Mariani, Lisabianca Bottero, C Mather, Stuart H. Orkin   +9 more
openalex   +1 more source

PRMT1‐Mediated SWI/SNF Complex Recruitment via SMARCC1 Drives IGF2BP2 Transcription to Enhance Carboplatin Resistance in Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
PRMT1 drives carboplatin resistance and tumor progression in head and neck squamous cell carcinoma (HNSCC) through a novel, methyltransferase‐independent mechanism. It recruits the SWI/SNF complex to activate IGF2BP2, promoting tumor growth and carboplatin resistance. PBX2 upregulates PRMT1, reinforcing this pathway. This study uncovers a non‐catalytic
Shixian Liu, Wentao Zhang, Weiwei Liu, Zhao Ding, Ruijing Zhang, Yuefeng Han, Zihao Niu, Mengdie Zhang, Hui Li, Dapeng Li, Zixi Wang, Jie Peng, Yu Wu, Yanxun Han, Zihui Xie, Jing Wu, Liang Qin, Zhongdong Hu, Xu Chen, Yunlong Hu, Yehai Liu, Shiyin Ma, Xiaojun Zha   +22 more
wiley   +1 more source

Cathepsin K-Positive Cell Lineage Promotes In Situ Dentin Formation Controlled by Nociceptive Sonic Hedgehog. [PDF]

Adv Sci (Weinh)
Xu R, Zhang X, Lin W, Wang Y, Zhang D, Jiang S, Liu L, Wang J, Luo X, Zhang X, Jing J, Yuan Q, Zhou C.   +12 more
europepmc   +1 more source

SCORT–Cas13d Nanotherapy Precisely Targets the ‘Undruggable’ Transcription Factor HoxB13 in Metastatic Prostate Cancer In Vivo

Advanced Science, EarlyView.
SCORT–Cas13d–pre‐gHoxB13 lipid nanoparticles precisely deliver Cas13d mRNA and guide RNAs to metastatic prostate tumors in the liver, knocking down the “undruggable” transcription factor HoxB13. This approach suppresses metastatic tumor growth, extends mouse survival, and does not induce major organ toxicity or immune activation, offering a safe and ...
Zhifen Cui, Furong Huang, Kun Fang, Jingyue Yan, Yuebao Zhang, Diana D. Kang, Yufan Zhou, Yue Zhao, Jeffrey I. Everitt, William Hankey, Andrew J Armstrong, Jiaoti Huang, Hongyan Wang, Victor X. Jin, Yizhou Dong, Qianben Wang   +15 more
wiley   +1 more source

Deep learning-based enhancement of fluorescence labeling for accurate cell lineage tracing during embryogenesis. [PDF]

Bioinformatics
Li Z, Xie D, Ma Y, Zhao C, You S, Yan H, Zhao Z.   +6 more
europepmc   +1 more source

Cell type atlas and lineage tree of a whole complex animal by single-cell transcriptomics

Science, 2018
M. Plass, Jordi Solana, F. A. Wolf, Salah Ayoub, Aristotelis Misios, Petar Glažar, B. Obermayer, Fabian J Theis, C. Kocks, N. Rajewsky   +9 more
semanticscholar   +1 more source

Engineered Tissue Models to Decode Host–Microbiota Interactions

Advanced Science, EarlyView.
Host–Microbiota interactions in the human body. Created in BioRender. Ghezzi, C. (2025) https://BioRender.com/ihivskg. Abstract A mutualistic co‐evolution exists between the host and its associated microbiota in the human body. Bacteria establish ecological niches in various tissues of the body, locally influencing their physiology and functions, but ...
Miryam Adelfio, Grace E. Callen, Xuesong He, Bruce J. Paster, Hatice Hasturk, Chiara E. Ghezzi   +5 more
wiley   +1 more source

Increased levels of lagging strand polymerase α in an adult stem cell lineage affect replication-coupled histone incorporation. [PDF]

Sci Adv
Davis BEM, Snedeker J, Ranjan R, Wooten M, Barton SS, Blundon J, Chen X.   +6 more
europepmc   +1 more source

THE DENDRITIC CELL LINEAGE IN HAEMOPOIESIS [PDF]

British Journal of Haematology, 1997
openaire   +3 more sources