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CELL LINEAGE OF NK CELL: EVIDENCE FOR T CELL LINEAGE
1982Publisher Summary This chapter examines whether the membrane phenotype of natural killer (NK) cells indicates an independent cell lineage both with regard to ontogenical differentiation and function or whether they belong to an already known cell population, especially the T-cell lineage.
Ko Okumura +3 more
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Cell Lineage Tracing: Colocalization of Cell Lineage Markers with a Fluorescent Reporter
2020Cell lineage tracing, an old technique which originated in the nineteenth century, regains popularity and relevance due to introduction of a more sensitive tomato fluorescent protein under the control of a ubiquitous promoter (Rosa 26 gene). In addition, various tissue specific CreERT2 mouse lines are widely available, making cell lineage tracing ...
Jian Q. Feng, Yan Jing, Patricia Simmer
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Simultaneous lineage tracing and cell-type identification using CRISPR–Cas9-induced genetic scars
Nature Biotechnology, 2018 A key goal of developmental biology is to understand how a single cell is transformed into a full-grown organism comprising many different cell types.
Jan Philipp Junker +2 more
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Cell death in the oligodendrocyte lineage
Journal of Neurobiology, 1992AbstractWe have recently found that about 50% of newly formed oligodendrocytes normally die in the developing rat optic nerve. When purified oligodendrocytes or their precursors are cultured in the absence of serum or added signalling molecules, they die rapidly with the characteristics of programmed cell death.
I. K. Hart +6 more
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Human cell-lineage imbalances [PDF]
Nature Reviews Genetics, 2021 Two new studies in Science use lineage tracking in humans to show that among the first few embryonic cells originating from post-fertilization cell divisions, there can be substantial imbalance in their contributions to mature tissues.
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Cell lineage in plant development
Current Opinion in Genetics & Development, 1991Lineage analyses in several plant species demonstrate that meristematic cells proliferate in a predictable manner to form the differentiated tissues of the mature shoot system. These studies also demonstrate, however, that the fates of meristematic cells are not absolutely dependent on their lineage. This variability indicates that interactions between
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The evolution of cell lineage in nematodes
Development, 1994ABSTRACT The invariant development of free-living nematodes combined with the extensive knowledge of Caenorhabditis elegans developmental biology provides an experimental system for an analysis of the evolution of developmental mechanisms. We have collected a number of new nematode species from soil samples.
Lynn K. Carta +2 more
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Cell differentiation lineage in the prostate
Differentiation, 2001Prostatic epithelium consists mainly of luminal and basal cells, which are presumed to differentiate from common progenitor/stem cells. We hypothesize that progenitor/stem cells are highly concentrated in the embryonic urogenital sinus epithelium from which prostatic epithelial buds develop.
Kristina A. Thayer +4 more
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The International journal of developmental biology, 1998
Studies of the role of cell lineage in development began in the 1870s, fell into decline in the first half of the 20th century, and were revived in the 1960s. This revival was attended by the introduction of new and powerful analytical techniques. Cell lineage can be inferred to have a causative role in developmental cell fate in embryos in which ...
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Studies of the role of cell lineage in development began in the 1870s, fell into decline in the first half of the 20th century, and were revived in the 1960s. This revival was attended by the introduction of new and powerful analytical techniques. Cell lineage can be inferred to have a causative role in developmental cell fate in embryos in which ...
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Glial cell lineage and development
Current Opinion in Neurobiology, 1994Recent studies on the development of glial cells are making rapid progress in two major directions. While the factors that control gliogenesis during the perinatal period are becoming more clearly characterized, so too is the relationship between gliogenesis and the patterning of the embryonic central nervous system as a whole.
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