Results 101 to 110 of about 12,310,648 (354)
Directed cell migration towards softer environments
Nature Materials, 2022 A. Isomursu +15 more
semanticscholar +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Shape of scaffold controlling the direction of cell migration
Biophysics and PhysicobiologyCell migration plays an important role in the development and maintenance of multicellular organisms. Factors that induce cell migration and mechanisms controlling their expression are important for determining the mechanisms of factor-induced cell ...
Hiroshi Sunami +2 more
doaj +1 more source
Role of glycosylation in hypoxia-driven cell migration and invasion
Cell Adhesion & Migration, 2019 Hypoxia, a common condition of the tumor microenvironment, induces changes in the proteome of cancer cells, mainly via HIF-1, a transcription factor conformed by a constitutively expressed β-subunit and an oxygen-regulated α-subunit.
Cecilia Arriagada +2 more
doaj +1 more source
Cell Adhesion & Migration, 2020 Krüppel-like factor 5 (KLF5) can both promote and suppress cell migration, but the underlying mechanisms have not been elucidated. In this study, we show that the function of KLF5 in epithelial-mesenchymal transition (EMT) and migration of liver cancer ...
Lan Sun +7 more
doaj +1 more source
Journal of Cell Biology, 2018 The nucleus has long been postulated to play a critical physical role during cell polarization and migration, but that role has not been defined or rigorously tested.
David M Graham +9 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Hyaluronan-CD44 interactions mediate contractility and migration in periodontal ligament cells
Cell Adhesion & Migration, 2019 The role of hyaluronan (HA) in periodontal healing has been speculated via its interaction with the CD44 receptor. While HA-CD44 interactions have previously been implicated in numerous cell types; effect and mechanism of exogenous HA on periodontal ...
Zeinab Al-Rekabi +5 more
doaj +1 more source
PI3K Isoform-Specific Regulation of Leader and Follower Cell Function for Collective Migration and Proliferation in Response to Injury [PDF]
, 2022 Morgan D. Basta +2 more
openalex +1 more source