Results 101 to 110 of about 12,335,534 (353)

LINC01614 Promotes Colorectal Cancer Cell Growth and Migration by Regulating miR‐217‐5p/HMGA1 Axis [PDF]

, 2023
Jiwei Jia, Pei Guo, Li Zhang, Weicheng Kong, Fangfang Wang   +4 more
openalex   +1 more source

Cell migration [PDF]

Current Biology, 2003
Horwitz, Rick, Webb, Donna
openaire   +2 more sources

Enucleated cells reveal differential roles of the nucleus in cell migration, polarity, and mechanotransduction

Journal of Cell Biology, 2018
The nucleus has long been postulated to play a critical physical role during cell polarization and migration, but that role has not been defined or rigorously tested.
David M Graham, T. Andersen, Lisa Sharek, G. Uzer, Katheryn E. Rothenberg, B. Hoffman, J. Rubin, M. Balland, J. Bear, K. Burridge   +9 more
semanticscholar   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Macrophage invasion: here, there and everywhere

Signal Transduction and Targeted Therapy, 2022
Lola C. Hernandez, Pablo J. Sáez
doaj   +1 more source

A biophysically-defined hyaluronic acid-based compound accelerates migration and stimulates the production of keratinocyte-derived neuromodulators

Cell Adhesion & Migration, 2019
Hyaluronic acid (HA) preparations are widely used in clinical practice and recent data suggest that commercially available HA-based compounds promote ulcer re-epithelialization and induce pain relief.
Annalisa La Gatta, Antonella D’Agostino, Chiara Schiraldi, Giuseppe Colella, Nicola Cirillo   +4 more
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Sirt1 and cell migration [PDF]

Cell Adhesion & Migration, 2010
Sirt1 is a type III histone deacetylase implicated in a wide range of physiological and pathophysiological roles. Acting though a myriad of non-histone substrates, Sirt1 modulates transcriptional regulation of energy metabolism and stress response, with important consequences on cell survival and a myriad of human pathologies.
openaire   +2 more sources

Cell Migration, Freshly Squeezed [PDF]

Cell, 2015
Migrating cells exhibit distinct motility modes and can switch between modes based on chemical or physical cues. Liu et al. and Ruprecht et al. now describe how confinement and contractility influence motility mode plasticity and instigate a mode termed stable bleb migration in embryonic and tumor cells.
openaire   +2 more sources

Integrins in Cell Migration [PDF]

, 2007
Integrins are cell-surface adhesion receptors that play a central role in regulating cell migration by mediating interactions between the extracellular matrix and the actin cytoskeleton. Substantial progress has been made in understanding the mechanisms by which the formation and breakdown of adhesions are regulated.
Keefe T, Chan, Christa L, Cortesio, Anna, Huttenlocher   +2 more
openaire   +2 more sources