Results 11 to 20 of about 1,804,531 (255)

Memory T Cell Migration [PDF]

Frontiers in Immunology, 2015
Immunological memory is a key feature of adaptive immunity. It provides the organism with long-lived and robust protection against infection. In organ transplantation, memory T cells pose a significant threat by causing allograft rejection that is ...
Qianqian eZhang, Qianqian eZhang, Fadi G. Lakkis   +2 more
doaj   +3 more sources

Trafficking and cell migration [PDF]

Traffic, 2009
The migration of single cells and epithelial sheets is of great importance for gastrulation and organ formation in developing embryos and, if misregulated, can have dire consequences e.g. during cancer metastasis. A keystone of cell migration is the regulation of adhesive contacts, which are dynamically assembled and disassembled via endocytosis. Here,
Florian, Ulrich, Carl-Philipp, Heisenberg   +1 more
openaire   +2 more sources

Dimensions in cell migration [PDF]

Current Opinion in Cell Biology, 2013
The importance of cell migration for both normal physiological functions and disease processes has been clear for the past 50 years. Although investigations of two-dimensional (2D) migration in regular tissue culture have elucidated many important molecular mechanisms, recent evidence suggests that cell migration depends profoundly on the ...
Doyle, Andrew D, Petrie, Ryan J, Kutys, Matthew L, Yamada, Kenneth M   +3 more
openaire   +4 more sources

Not just a marker: CD34 on human hematopoietic stem/progenitor cells dominates vascular selectin binding along with CD44

Blood Advances, 2017
: CD34 is routinely used to identify and isolate human hematopoietic stem/progenitor cells (HSPCs) for use clinically in bone marrow transplantation, but its function on these cells remains elusive.
Dina B. AbuSamra, Fajr A. Aleisa, Asma S. Al-Amoodi, Heba M. Jalal Ahmed, Chee Jia Chin, Ayman F. Abuelela, Ptissam Bergam, Rachid Sougrat, Jasmeen S. Merzaban   +8 more
doaj   +1 more source

Modelling adhesion-independent cell migration [PDF]

, 2020
A two-dimensional mathematical model for cells migrating without adhesion capabilities is presented and analyzed. Cells are represented by their cortex, which is modelled as an elastic curve, subject to an internal pressure force.
Jankowiak, Gaspard, Peurichard, Diane, Reversat, Anne, Schmeiser, Christian, Sixt, Michael   +4 more
core   +5 more sources

Spectrin binding motifs regulate Scribble cortical dynamics and polarity function

eLife, 2015
The tumor suppressor protein Scribble (SCRIB) plays an evolutionary conserved role in cell polarity. Despite being central for its function, the molecular basis of SCRIB recruitment and stabilization at the cell cortex is poorly understood.
Batiste Boëda, Sandrine Etienne-Manneville   +1 more
doaj   +1 more source

MODELLING THE INFLUENCE OF NUCLEUS ELASTICITY ON CELL INVASION IN FIBER NETWORKS AND MICROCHANNELS [PDF]

, 2013
Cell migration in highly constrained extracellular matrices is exploited in scaffold-based tissue engineering and is fundamental in a wide variety of physiological and pathological phenomena, among others in cancer invasion and development. Research into
Preziosi, Luigi, Scianna, Marco
core   +1 more source

The C. elegans tailless/Tlx homolog nhr-67 regulates a stage-specific program of linker cell migration in male gonadogenesis [PDF]

, 2009
Cell migration is a common event during organogenesis, yet little is known about how migration is temporally coordinated with organ development. We are investigating stage-specific programs of cell migration using the linker cell (LC), a migratory cell ...
Abraham, Affolter, Ambros, Antebi, Asahina, Blelloch, Brenner, Cardoso, Chamberlin, Chisholm, Chitwood, DeMeo, Duchek, Euling, Fernandes, Ferreira, Gaudet, Gaudet, Ghysen, Gissendanner, Henderson, Henderson, Hoch, Hodgkin, Hollemann, Kamath, Kimble, Kitambi, Klass, Kuntz, Lehmann, Lucanic, Lundquist, Maduro, Margolis, Meighan, Meighan, Monaghan, Montell, Moss, Motola, Nettles, Ou, Pankratz, Pearson, Pignoni, Randall, Robson, Roy, Sarin, Sauka-Spengler, Siegfried, Su, Sulston, Sulston, Towers, Vogel, Wang, Younossi-Hartenstein, Yu, Ziel, Zipkin   +61 more
core   +3 more sources

Molecular signatures of cell migration in C. elegans Q neuroblasts. [PDF]

, 2009
Metazoan cell movement has been studied extensively in vitro, but cell migration in living animals is much less well understood. In this report, we have studied the Caenorhabditis elegans Q neuroblast lineage during larval development, developing live ...
Avraamides, Baum, Branda, Burdine, Cordes, de Curtis, Guangshuo Ou, Gupton, Heasman, Horvitz, Hynes, Jaffe, Keely, Kurosaka, Lehmann, Locascio, Lundquist, Meighan, Ng, Ou, Palecek, Pankov, Pollard, Ridley, Ronald D. Vale, Simpson, Sulston, Webb, Yamada, Yamaguchi, Zipkin   +30 more
core   +2 more sources

Cell migration in Drosophila

Current Opinion in Genetics & Development, 1999
Recent genetic studies in Drosophila have identified signals that direct cell movement, mechanisms that transduce such signals within migrating cells and some of the molecular machinery underlying cell motility. Activation of the fibroblast growth factor receptor signaling pathway is required for migration of the cells of the developing respiratory ...
A, Forbes, R, Lehmann
openaire   +2 more sources