Results 11 to 20 of about 441,437 (348)
Cell Polarity and Development [PDF]
Journal of Integrative Plant Biology, 2013 Remko Offringa, Jürgen Kleine‐Vehn
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Cell autonomous polarization by the planar cell polarity signaling pathway. [PDF]
Nat Commun, 2023 Abstract As epithelial cells polarize in the tissue plane, the Planar Cell Polarity (PCP) signaling module segregates two distinct molecular subcomplexes to opposite sides of cells. Homodimers of the atypical cadherin Flamingo form bridges linking opposite complexes in neighboring cells, coordinating their direction of polarization ...
Weiner AT +5 more
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Cell Polarity from Cell Division [PDF]
Developmental Cell, 2007 Apical-basal polarity of epithelial cells is critical for their symmetric versus asymmetric division and commonly thought to be established in interphase. In a novel type of cell division termed "mirror-symmetric", apical cell constituents accumulate during M-phase at the cleavage furrow, resulting in epithelial daughter cells with opposite apical ...
Knust, E., Huttner, W.
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Rho and Rab Family Small GTPases in the Regulation of Membrane Polarity in Epithelial Cells
Frontiers in Cell and Developmental Biology, 2022 Membrane polarity, defined as the asymmetric distribution of lipids and proteins in the plasma membrane, is a critical prerequisite for the development of multicellular tissues, such as epithelia and endothelia.
Klaus Ebnet +5 more
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Cell polarity inside-out [PDF]
Current Opinion in Cell Biology, 2020 Cell Polarity is defined as the structural, morphological, and functional asymmetry along an axis. This fundamental process can be separated into initiation or establishment, commonly referred to as symmetry breaking, and maintenance. For both steps, tight spatial and temporal control of signaling and cellular organization is critical and can be ...
Etienne-Manneville, Sandrine +1 more
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Membrane recruitment of the polarity protein Scribble by the cell adhesion receptor TMIGD1
Communications Biology, 2023 Scribble (Scrib) is a multidomain polarity protein and member of the leucine-rich repeat and PDZ domain (LAP) protein family. A loss of Scrib expression is associated with disturbed apical-basal polarity and tumor formation.
Eva-Maria Thüring +9 more
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Cortactin-dependent control of Par1b-regulated epithelial cell polarity in Helicobacter infection [PDF]
Cell InsightIrshad Sharafutdinov +8 more
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Polarized cells, polar actions
Journal of Bacteriology, 1993 The recognition of polar bacterial organization is just emerging. The examples of polar localization given here are from a variety of bacterial species and concern a disparate array of cellular functions. A number of well-characterized instances of polar localization of bacterial proteins, including the chemoreceptor complex in both C. crescentus and E.
J R, Maddock, M R, Alley, L, Shapiro
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Spectrin binding motifs regulate Scribble cortical dynamics and polarity function
eLife, 2015 The tumor suppressor protein Scribble (SCRIB) plays an evolutionary conserved role in cell polarity. Despite being central for its function, the molecular basis of SCRIB recruitment and stabilization at the cell cortex is poorly understood.
Batiste Boëda +1 more
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