Results 21 to 30 of about 441,437 (348)
Cell polarity: Fixing cell polarity with Pins [PDF]
Current Biology, 2000 A protein complex is assembled in a step-wise manner at the apical pole of Drosophila neuroblasts. This complex organizes the apical-basal polarity of asymmetrically dividing neuroblasts, and may act via G-protein signalling.
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Neural Tube Defects: From a Proteomic Standpoint
Metabolites, 2015 Neural tube defects (NTDs) are congenital birth defects classified according to their resulting morphological characteristics in newborn patients. Current diagnosis of NTDs relies largely on the structural evaluation of fetuses using ultrasound imaging ...
Tania M. Puvirajesinghe, Jean-Paul Borg
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Memristive excitable cellular automata [PDF]
, 2011 The memristor is a device whose resistance changes depending on the polarity and magnitude of a voltage applied to the device's terminals. We design a minimalistic model of a regular network of memristors using structurally-dynamic cellular automata ...
Adamatzky A. +5 more
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Annual Review of Cell and Developmental Biology, 2017 A conserved molecular machinery centered on the Cdc42 GTPase regulates cell polarity in diverse organisms. Here we review findings from budding and fission yeasts that reveal both a conserved core polarity circuit and several adaptations that each organism exploits to fulfill the needs of its lifestyle.
Jian-Geng, Chiou +2 more
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Biomolecules, 2019 Drosophila Schneider 2 (S2) cells are a simple and powerful system commonly used in cell biology because they are well suited for high resolution microscopy and RNAi-mediated depletion.
Mariana Osswald +2 more
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Mechanics and polarity in cell motility [PDF]
, 2016 The motility of a fish keratocyte on a flat substrate exhibits two distinct regimes: the non-migrating and the migrating one. In both configurations the shape is fixed in time and, when the cell is moving, the velocity is constant in magnitude and ...
Ambrosi, Davide, Zanzottera, Anna
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Cell polarity: mechanochemical patterning
Trends in Cell Biology, 2013 Nearly every cell type exhibits some form of polarity, yet the molecular mechanisms vary widely. Here we examine what we term 'chemical systems' where cell polarization arises through biochemical interactions in signaling pathways, 'mechanical systems' where cells polarize due to forces, stresses and transport, and 'mechanochemical systems' where ...
Nathan W. Goehring, Stephan W. Grill
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Mechanisms of cell polarization [PDF]
Current Opinion in Systems Biology, 2017 Cell polarization is a key step in the migration, development, and organization of eukaryotic cells, both at the single cell and multicellular level. Research on the mechanisms that give rise to polarization of a given cell, and organization of polarity within a tissue has led to new understanding across cellular and developmental biology.
Wouter-Jan, Rappel +1 more
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Frontiers in Microbiology, 2022 The C-terminus of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) protein E contains a PBM (PDZ-binding motif) targeting PDZ (PSD-95/Dlg/ZO-1) domains, which is identical to the PBM of SARS-CoV.
Yanlei Zhu +9 more
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Cell polarity and planar cell polarity (PCP) in spermatogenesis
Seminars in Cell & Developmental Biology, 2018 In adult mammalian testes, spermatids, most notably step 17-19 spermatids in stage IV-VIII tubules, are aligned with their heads pointing toward the basement membrane and their tails toward the tubule lumen. On the other hand, these polarized spermatids also align across the plane of seminiferous epithelium, mimicking planar cell polarity (PCP) found ...
Haiqi, Chen +5 more
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