Results 1 to 10 of about 149 (146)
Cell Proliferation in Neuroblastoma [PDF]
Neuroblastoma, the most common extracranial solid tumor of childhood, continues to carry a dismal prognosis for children diagnosed with advanced stage or relapsed disease. This review focuses upon factors responsible for cell proliferation in neuroblastoma including transcription factors, kinases, and regulators of the cell cycle.
Laura L. Stafman, Elizabeth A. Beierle
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The centrosome and cell proliferation.
Centrosomes are frequently amplified in cancer cells. Increased numbers of centrosomes can give rise to multipolar spindles in mitosis, and thereby lead to the formation of aneuploid daughter cells. However, whether centrosome amplification is a cause or a consequence of cancer is unclear.
Srsen, Vlastimil, Merdes, Andreas
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Cell proliferation and cancer.
The discovery that phosphorylation of selected proteins by cyclin-dependent kinases is the engine which makes the cycle run provides a new image of the control of proliferation and of its deregulation. The high conservation of this machinery in the different eukaryotic organisms emphasizes its early origin and its importance for life. It also makes the
Lopez-Saez, J.F.+3 more
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On proliferation of the cells of the liver [PDF]
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Regulation of mesangial cell proliferation [PDF]
Regardless of the source of injury, an imbalance in the control of mesangial cell proliferation appears to play a direct role in the degree of progressive renal injury and glomerulosclerosis. Some of the regulatory mechanisms include specific soluble or non-soluble extracellular factors and a complex array of receptor-mediated signals that control the ...
Stefan Lang+2 more
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Cell Proliferation in Retinal Transplants
The MIB-1 antibody against a nuclear protein Ki-67 was used to study the proliferation of cells in the rabbit retinal transplants. Fragmented pieces of embryonic day 15 rabbit retinas were transplanted into the subretinal space of adult rabbits and allowed to survive for different times.
Rajesh K. Sharma, Berndt Ehinger
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T cells: A proliferation of costimulatory molecules [PDF]
The identification and characterization of a newly extended family of molecules related to the T-cell costimulatory proteins CD28 and B7 suggests that a distinct form of costimulatory signals could be important for effector T-cell responses outside of lymphoid tissues.
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Cell Proliferation in Normal Epidermis
A detailed examination of cell proliferation kinetics in normal human epidermis is presented. Using tritiated thymidine with autoradiographic techniques, proliferative and differentiated cell kinetics are defined and interrelated. The proliferative compartment of normal epidermis has a cell cycle duration (Tc) of 311 h derived from 3 components: the ...
Gerald D. Weinstein+2 more
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The Stochastic Theory of Cell Proliferation
A stochastic theory of cell kinetics has been developed based on a realistic model of cell proliferation. A characteristic transit time, t(i), has been assigned to each of the four states (G(1), S, G(2), M) of the cell cycle. The actual transit time, t(i), for any cell is represented by a distribution around t(i) with a variance sigma(i) (2).
G.J. Dienes+2 more
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