Results 21 to 30 of about 12,836,766 (354)

Stem cells for myocardial repair [PDF]

Thrombosis and Haemostasis, 2010
SummaryThere is a growing interest in the clinical application for stem cell as a novel therapy for treatment of acute myocardial infarction and chronic myocardial ischaemia. The initial premise is the transplanted exogenous stem cells can engraft and integrate with host myocardium for cardiac regeneration.
Liu, Y, Liao, SY, Lian, Q, Siu, CW, Tse, HF   +4 more
openaire   +4 more sources

NEDD4-1 deficiency impairs satellite cell function during skeletal muscle regeneration

Biological Research, 2023
Background Satellite cells are tissue-specific stem cells primarily responsible for the regenerative capacity of skeletal muscle. Satellite cell function and maintenance are regulated by extrinsic and intrinsic mechanisms, including the ubiquitin ...
Felipe Cabezas, Claudio Cabello-Verrugio, Natalia González, Jeremy Salas, Manuel J. Ramírez, Eduardo de la Vega, Hugo C. Olguín   +6 more
doaj   +1 more source

Cell aging preserves cellular immortality in the presence of lethal levels of damage. [PDF]

, 2019
Cellular aging, a progressive functional decline driven by damage accumulation, often culminates in the mortality of a cell lineage. Certain lineages, however, are able to sustain long-lasting immortality, as prominently exemplified by stem cells.
Chao, Lin, Proenca, Audrey Menegaz, Qiu, Andrew, Rang, Camilla Ulla, Shi, Chao   +4 more
core   +3 more sources

Oxidative stress and docosahexaenoic acid injury lead to increased necroptosis and ferroptosis in retinal pigment epithelium

Scientific Reports, 2023
Age-related macular degeneration (AMD) is a complex disease caused by different genetic and environmental risk factors leading to loss of cells in the central part of the retina.
Almar Neiteler, Anwar A. Palakkan, Kevin M. Gallagher, James A. Ross   +3 more
doaj   +1 more source

NaNog: A pluripotency homeobox (master) molecule. [PDF]

, 2015
One of the most intriguing aspects of cell biology is the state of pluripotency, where the cell is capable of self-renewal for as many times as deemed necessary , then at a specified time can differentiate into any type of cell. This fundamental process
Aguib, YE, Allouba, MH, ElGuindy, AM, Krishnamoorthy, N, Yacoub, MH   +4 more
core   +1 more source

Proteomics and transcriptomics of peripheral nerve tissue and cells unravel new aspects of the human Schwann cell repair phenotype

Glia, 2016
The remarkable feature of Schwann cells (SCs) to transform into a repair phenotype turned the spotlight on this powerful cell type. SCs provide the regenerative environment for axonal re‐growth after peripheral nerve injury (PNI) and play a vital role in
T. Weiss, S. Taschner-Mandl, A. Bileck, A. Slany, F. Kromp, F. Rifatbegovic, C. Frech, R. Windhager, Hugo Kitzinger, C. Tzou, P. Ambros, C. Gerner, I. Ambros   +12 more
semanticscholar   +1 more source

RAD6-RAD18-RAD5-pathway-dependent tolerance to chronic low-dose ultraviolet light [PDF]

, 2009
In nature, organisms are exposed to chronic low- dose ultraviolet light ( CLUV) as opposed to the acute high doses common to laboratory experiments. Analysis of the cellular response to acute high-dose exposure has delineated the importance of direct DNA
Carr, Antony M, Hishida, T, Iwasaki, H, Kubota, Y   +3 more
core   +1 more source

c-Abl Kinase Is Required for Satellite Cell Function Through Pax7 Regulation

Frontiers in Cell and Developmental Biology, 2021
Satellite cells (SCs) are tissue-specific stem cells responsible for adult skeletal muscle regeneration and maintenance. SCs function is critically dependent on two families of transcription factors: the paired box (Pax) involved in specification and ...
Fabián Montecino, Natalia González, Natasha Blanco, Manuel J. Ramírez, Adrián González-Martín, Alejandra R. Alvarez, Hugo Olguín   +6 more
doaj   +1 more source

Only complete rejoining of DNA strand breaks after UVC allows K562 cell proliferation and DMSO induction of erythropoiesis [PDF]

, 2008
DNA strand breaks are early intermediates of the repair of UVC-induced DNA damage, however, since they severely impair cellular activities, their presence should be limited in time.
AVALLONE, BICE, FORESTI, MAGDA
core   +1 more source

Mesenchymal Stem Cell Migration and Tissue Repair

Cells, 2019
Mesenchymal stem cells (MSCs) are multilineage cells with the ability to self-renew and differentiate into a variety of cell types, which play key roles in tissue healing and regenerative medicine.
Xiaorong Fu, Ge Liu, Alexander Halim, Y. Ju, Qing Luo, Guanbin Song   +5 more
semanticscholar   +1 more source