Results 51 to 60 of about 9,650,343 (306)

Adaptive evolution of Pseudomonas putida in the presence of fluoride exposes novel functions of a benzoate transporter

Journal of Bacteriology
Fluoride (F−), the anionic form of fluorine and the 13th most abundant element in Earth’s crust, is toxic to most organisms above relatively low threshold concentrations.
Lea Ets, Heili Ilves, Lisette Juhe, Tanel Ilmjärv, Òscar Puiggené, Pablo Iván Nikel, Maia Kivisaar   +6 more
doaj   +1 more source

rRNA biogenesis regulates mouse 2C-like state by 3D structure reorganization of peri-nucleolar heterochromatin

Nature Communications, 2021
The role of the nucleolus in cell fate is not well known. Here the authors show nucleolar integrity maintained by rRNA-mediated liquid-liquid phase separation and 3D chromatin structure of perinucleolar heterochromatin regulates the fate transition of ...
Hua Yu, Zhen Sun, Tianyu Tan, Hongru Pan, Jing Zhao, Ling Zhang, Jiayu Chen, Anhua Lei, Yuqing Zhu, Lang Chen, Yuyan Xu, Yaxin Liu, Ming Chen, Jinghao Sheng, Zhengping Xu, Pengxu Qian, Cheng Li, Shaorong Gao, George Q. Daley, Jin Zhang   +19 more
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Transitional Cell Carcinoma of the Ovary

Taiwanese Journal of Obstetrics and Gynecology, 2006
Transitional cell carcinoma (TCC) of the ovary is a rare, recently recognized, subtype of ovarian surface epithelial cancer. We present a case of TCC of the ovary, managed by staging operation and followed by postoperative chemotherapy with carboplatin and cyclophosphamide.A 67-year-old postmenopausal woman presented with a 2-year history of ...
Chia-Hui Lin, Fu-Shing Liu, Esther Shih-Chu Ho   +2 more
openaire   +3 more sources

Regulatory T cell homing and activation is a signature of neonatal sepsis

Frontiers in Immunology
Regulatory T cells (Treg) play a prominent role in utero tolerating non-inherited maternal antigens and in regulating immune responses against pathogens at birth.
Darius Sossou, Darius Sossou, Darius Sossou, Sem Ezinmegnon, Sem Ezinmegnon, Gino Agbota, Gino Agbota, Komi Gbedande, Komi Gbedande, Manfred Accrombessi, Manfred Accrombessi, Achille Massougbodji, Marceline d’Almeida, Jules M. Alao, Ida Dossou-Dagba, Alexandre Pachot, Laurence Vachot, Karen Brengel-Pesce, Gilles Cottrell, Akadiri Yessoufou, Valérie Briand, Pierre Tissières, Pierre Tissières, Pierre Tissières, Nadine Fievet   +24 more
doaj   +1 more source

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad, Ohad Atia, Osama Tanous, Dafna Brik Simon, Michal Dvori, Miriam Cohen, Tracie A. Goldberg, Efraim Bilavsky, Joanne Yacobovich, Orna Steinberg‐Shemer   +9 more
wiley   +1 more source

Bone Mineral Density After Contemporary Treatment for Acute Lymphoblastic Leukaemia: A Matched Cross‐Sectional Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen, Mette Tiedemann Skipper, Niels Holtum Birkebæk, Kjeld Schmiegelow, Thomas Leth Frandsen, Bente Langdahl, Rikke Beck Jensen, Asger Roer Pedersen, Christian Mølgaard, Liv Andrés‐Jensen, Birgitte Klug Albertsen   +10 more
wiley   +1 more source

Investigating the properties of cancer stem cells and epithelial to mesenchymal transition in human prostate cancer [PDF]

, 2012
In recent years, the cancer stem cell hypothesis has emerged as a compelling but controversial model of cancer progression. Contrary to the clonal evolution model, the cancer stem cell hypothesis postulates that, akin to normal tissues, tumours are ...
Dunning-Foreman, NL
core  

Polarity reversal primes cell scattering during epithelial to mesenchymal transition

, 2015
Polarity reversal primes cell scattering during epithelial to mesenchymal transition.
Prioux, M., Blin, G., Théry, Manuel, Truchet, Sandrine, Bessy, T., Tseng, Q., Burute, Mithila, Letort, G., Young, J., Filhol, Odile   +9 more
core   +4 more sources

Phase transition in a cell fluid model

Condensed Matter Physics, 2017
We propose a method of describing a phase transition in a cell fluid model with pair interaction potential that includes repulsive and attractive parts.
M.P. Kozlovskii, O.A. Dobush
doaj   +1 more source