Results 151 to 160 of about 2,039,775 (263)

Tunability of the bandgap of SnS by variation of the cell volume by alloying with A.E. elements. [PDF]

Sci Rep, 2022
Kawamura F, Song Y, Murata H, Tampo H, Nagai T, Koida T, Imura M, Yamada N.   +7 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Cytoskeletal activation of NHE1 regulates mechanosensitive cell volume adaptation and proliferation. [PDF]

Cell Rep
Ni Q, Ge Z, Li Y, Shatkin G, Fu J, Sen A, Bera K, Yang Y, Wang Y, Wu Y, Nogueira Vasconcelos AC, Yan Y, Lin D, Feinberg AP, Konstantopoulos K, Sun SX.   +15 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Exploring the role of macromolecular crowding and TNFR1 in cell volume control. [PDF]

Elife
Biswas P, Roy P, Jana S, Ray D, Das J, Chaudhuri B, Basunia RR, Sinha B, Sinha DK.   +8 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Corrigendum: Cell volume restriction by mercury chloride reduces M1-like inflammatory response of bone marrow-derived macrophages. [PDF]

Front Pharmacol, 2023
Chuang YC, Wu SY, Huang YC, Peng CK, Tang SE, Huang KL.   +5 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Piezo1, the new actor in cell volume regulation. [PDF]

Pflugers Arch
Michelucci A, Catacuzzeno L.
europepmc   +1 more source

Platelet and Red Blood Cell Volume Indices in Patients with Rheumatoid Arthritis: A Systematic Review and Meta-Analysis. [PDF]

Diagnostics (Basel), 2022
Zinellu A, Mangoni AA.
europepmc   +1 more source