Sirt3 Rescues Porphyromonas gingivalis‐Impaired Cementogenesis via SOD2 Deacetylation [PDF]
Sirt3 deacetylated SOD2 via K68 to orchestrate P.g.‐impaired cementogenesis. Reestablishment of the Sirt3/SOD2 axis by honokiol reduced SOD2 acetylation and facilitated cementogenesis. ABSTRACT The keystone pathogen Porphyromonas gingivalis (P.g.) is responsible for cementum resorption in periodontitis; however, the mechanism involved in it remains ...
Zhengguo Cao
exaly +5 more sources
A Reciprocal Interaction between β-Catenin and Osterix in Cementogenesis
Although accumulating evidence indicates that both β-catenin and osterix (Osx) are essential for bone and tooth development, few studies have investigated the interaction of these two key proteins in the context of cementogenesis.
Hwajung Choi +5 more
doaj +3 more sources
Coronal Cementum and Reduced Enamel Epithelium on Occlusal Surface of Impacted Wisdom Tooth in a Human [PDF]
Background: There is only limited research on the coronal cementum of a tooth, and the mechanisms of its forming process are not well-defined. This report presents a coronal cementum on the occlusal surfaces of enamel in an impacted wisdom tooth in a ...
Naohiro Horie +8 more
doaj +2 more sources
Counter-regulatory phosphatases TNAP and NPP1 temporally regulate tooth root cementogenesis [PDF]
Cementum is critical for anchoring the insertion of periodontal ligament fibers to the tooth root. Several aspects of cementogenesis remain unclear, including differences between acellular cementum and cellular cementum, and between cementum and bone.
Zweifler, Laura E. +6 more
openaire +6 more sources
Cementogenesis in Patients with Localized Aggressive Periodontitis
Objectives: The aim of this study was to determine the cementum thickness in the first molars of patients with localized aggressive periodontitis (LAP) compared to healthy individuals.
Mojgan Paknejad +6 more
doaj +2 more sources
Kdm6b/Pdk1 Glycolytic Pathway-Driven Zeb2 Lactylation Promotes Cementogenesis
Aim or purpose: This study investigates the role of KDM6B-mediated glycolytic reprogramming in cementum regeneration, addressing the unclear mechanisms linking epigenetic-metabolic crosstalk to cementoblast mineralization.
Wang Xiaoxuan +3 more
doaj +2 more sources
Central role of pyrophosphate in acellular cementum formation. [PDF]
BackgroundInorganic pyrophosphate (PP(i)) is a physiologic inhibitor of hydroxyapatite mineral precipitation involved in regulating mineralized tissue development and pathologic calcification.
Brian L Foster +9 more
doaj +4 more sources
Histologic and micro-computed tomography confirmation of cementogenesis over calcium-enriched mixture cement in a human permanent tooth [PDF]
Saeed Asgary, Nafise Shamloo
doaj +2 more sources
CBCT-Assisted Microsurgical Management of Dual Periapical Lesions Involving Vital and Previously Endodontically Treated Maxillary Molars: A Case Report. [PDF]
This graphical abstract summarizes a case where CBCT‐assisted apical microsurgery with retrograde vital pulp therapy (retroVPT) using CEM cement successfully resolved dual periapical lesions involving a vital and a previously treated molar, preserving pulp vitality and achieving complete periapical healing without conventional root canal treatment ...
Asgary S.
europepmc +2 more sources
KDM6B-Mediated HADHA Demethylation/Lactylation Regulates Cementogenesis. [PDF]
Cementum, a bone-like tissue, is an essential component of periodontium, and periodontitis can lead to degenerative changes in the cementum, eventually resulting in tooth loss. The therapeutic strategy for advanced periodontitis is to achieve periodontal regeneration, of which cementum regeneration is a key criterion. Cementoblasts are responsible for
Yang Z +10 more
europepmc +3 more sources

