Results 61 to 70 of about 7,373 (166)

A Cross-Sectional Study of Compositional and Functional Profiles of Gut Microbiota in Sardinian Centenarians

mSystems, 2019
Sardinia, Italy, has a high prevalence of residents who live more than 100 years. The reasons for longevity in this isolated region are currently unknown. Gut microbiota may hold a clue.
Lu Wu, Tiansheng Zeng, Angelo Zinellu, Salvatore Rubino, David J. Kelvin, Ciriaco Carru   +5 more
doaj   +1 more source

A Cellular and Transcriptomic Atlas of the Aged Mouse Hematopoietic System

Aging Cell, Volume 25, Issue 2, February 2026.
Transcriptomic and cellular atlas of peripheral blood mononuclear cells (PBMCs) and stem and progenitor cells of the hematopoietic compartment (HSPCs) of aged C57Bl/6J mice. Analysis shows global alterations related to immune function and identifies potential pathways and cell populations that can be targeted for therapeutic intervention.
Ryan R. White, Kun Xiong, Matthew Wakai, Allison Surian, Christina Adler, Nicole Negron, Min Ni, Tea Shavlakadze, Yu Bai, David J. Glass   +9 more
wiley   +1 more source

Relationships of Hyperhomocysteinemia and Hyperuricemia With Metabolic Syndrome and Renal Function in Chinese Centenarians

Frontiers in Endocrinology, 2018
As the first time worldwide, this study aimed to investigate the relationships of hyperhomocysteinemia and hyperuricemia with metabolic syndrome (MetS) and renal function in Chinese centenarians. The China Hainan Centenarian Cohort Study was performed in
Shihui Fu, Shihui Fu, Yao Yao, Yao Yao, Yali Zhao, Fuxin Luan   +5 more
doaj   +1 more source

Association between anthropometric measures and cardiovascular disease (CVD) risk factors in Hainan centenarians: investigation based on the Centenarian’s health study

BMC Cardiovascular Disorders, 2018
Background Centenarians refer to a special group who have outlived most of their fellows. Body shape and abdominal obesity have been identified as cardiovascular disease (CVD) risk factors.
Qiao Zhu, Xiao-Bing Wang, Yao Yao, Chao-Xue Ning, Xiao-Ping Chen, Fu-Xin Luan, Ya-Li Zhao   +6 more
doaj   +1 more source

The ‘autoimmunome’ of centenarians

Journal of Translational Autoimmunity
Objective: To identify signature proteins potentially linked to resistance to autoimmunity in the blood of centenarians. Methods: We conducted in silico data mining of previously published proteomic results using the Search Tool for the Retrieval of ...
Pedro Carrera-Bastos, Abel Plaza-Florido, Alejandro Santos-Lozano, Vânia Borba, Gabriel Rodríguez-Romo, Celia García-Chico, Simone Lista, Gonzalo Saco-Ledo, Enzo Emanuele, Yehuda Shoenfeld, Alejandro Lucia   +10 more
doaj   +1 more source

Functional capacity and level of physical activity in centenarians of Florianópolis, Brazil

Revista da Educação Física, 2016
Aim: To compare the level of physical activity and functional capacity of centenarians from Florianópolis, Brazil. Methods: To measure the level of physical activity and functional capacity, pedometer and the Katz scale, respectively, were used.
Inês Amanda Streit, Artur Rodrigues Fortunato, Eduardo Hauser, Giovana Zarpellon Mazo   +3 more
doaj  

Lipid profile in elderly and centenarian subjects in Kazakhstan: a case-control study

Central Asian Journal of Medical Hypotheses and Ethics
Introduction. The health of centenarians is a major focus in global studies. Dyslipidemia is directly linked to the risk of cardiovascular diseases, which pose a growing burden on healthcare due to the increasing elderly population.
Yu. Ganzhula, Zh. Borykbay, V. Tkachev, S. Urazova, L. Chulenbayeva   +4 more
doaj   +1 more source

Age-dependent dynamics of screening metabolic parameters in long-livers and its biophysical estimation [PDF]

Саратовский научно-медицинский журнал, 2015
The purpose of the study: to examine age-dependent dynamics of parameters of biochemical screening in long-livers. Material and methods. The study included 201 long-livers divided (Saratov) into two groups: the main group (centenarians) and the control ...
Denisova Т.Р., Malinova L.I., Cherevatova О.М.   +2 more
doaj  

Serum metabolic and microbial profiling yields insights into promoting effect of tryptophan‐related metabolites for health longevity in centenarians

iMeta
A better understanding of the characteristic serum metabolites and microbiota from the gut and oral cavity in centenarians could contribute to elucidating the mutual connections among them and would help provide information to achieve healthy longevity ...
Xiaorou Qiu, Chao Mu, Jie Hu, Jiaxin Yu, Wenbo Tang, Yueli Liu, Yongmei Huang, Yixian Lu, Peihua Tang, Jingzhen Wu, Zixuan Huang, Xianlin Mei, Huaguo Xiang, Hao Lin, Yi Qi, Hui Luo, Xuemeng Li   +16 more
doaj   +1 more source

Association of anemia with all-cause mortality in Chinese centenarians: a prospective cohort study

The Journal of Nutrition, Health and Aging
Objectives: This study aimed to examine the relationship between anemia and all-cause mortality in Chinese centenarians. Design: Prospective cohort study.
Wangping Jia, Shengshu Wang, Shanshan Yang, Yali Zhao, Qiao Zhu, Chaoxue Ning, Yujian Chen, Shihui Fu, Yizhi Chen, Yao He, Miao Liu   +10 more
doaj   +1 more source