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Exploration of cerebral vasospasm from the perspective of microparticles
Frontiers in Neuroscience, 2022 Cerebral vasospasm is a frequently encountered clinical problem, especially in patients with traumatic brain injury and subarachnoid hemorrhage. Continued cerebral vasospasm can cause cerebral ischemia, even infarction and delayed ischemic neurologic ...
Yalong Gao +7 more
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Viral diseases of the central nervous system [PDF]
Current Opinion in Virology, 2015 Virus-induced diseases of the central nervous system (CNS) represent a significant burden to human health worldwide. The complexity of these diseases is influenced by the sheer number of different neurotropic viruses, the diverse routes of CNS entry, viral tropism, and the immune system.
Phillip A, Swanson, Dorian B, McGavern
openaire +2 more sources
Glucose metabolism: A link between traumatic brain injury and Alzheimer’s disease
Chinese Journal of Traumatology, 2021 Traumatic brain injury (TBI), a growing public health problem, is a leading cause of death and disability worldwide, although its prevention measures and clinical cares are substantially improved.
Xiao-Jian Xu +5 more
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[Role of succinylation modification in central nervous system diseases]. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue BanGu M, Ren K, Zhang Z, Chen X.
europepmc +2 more sources
Targeting sialylation to treat central nervous system diseases.
, 2021 Sialic acid-binding immunoglobulin-type lectins (SIGLECs) are membrane receptors that are preferentially expressed on immune cells and recognize sialylated proteins, lipids, and RNA.
Neumann, Harald +2 more
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Phosphatidylserine, inflammation, and central nervous system diseases
Frontiers in Aging Neuroscience, 2022 Phosphatidylserine (PS) is an anionic phospholipid in the eukaryotic membrane and is abundant in the brain. Accumulated studies have revealed that PS is involved in the multiple functions of the brain, such as activation of membrane signaling pathways ...
Xiaohua Ma +7 more
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Crossing the blood-brain barrier: a review on drug delivery strategies for treatment of the central nervous system diseases [PDF]
, 2019 Many drugs have been designed to treat diseases of the central nervous system (CNS), especially neurodegenerative diseases. However, the presence of tight junctions at the blood-brain barrier has often compromised the efficiency of drug delivery to ...
Ling, King Hwa +6 more
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Nanomedicine strategies for central nervous system (CNS) diseases
Frontiers in Biomaterials Science, 2023 The blood-brain barrier (BBB) is a crucial part of brain anatomy as it is a specialized, protective barrier that ensures proper nutrient transport to the brain, ultimately leading to regulating proper brain function.
Shreya Nagri, Olivia Rice, Yupeng Chen
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Frontiers in Psychiatry, 2020 It has been found that antipsychotic-naïve patients with first-episode psychosis (FEP) present with impaired hormonal regulation of appetite in terms of low leptin and high insulin levels (the adipoinsular axis).
Michał Lis +5 more
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PPARα Modulation-Based Therapy in Central Nervous System Diseases
Life, 2021 The burden of neurodegenerative diseases in the central nervous system (CNS) is increasing globally. There are various risk factors for the development and progression of CNS diseases, such as inflammatory responses and metabolic derangements.
Deokho Lee +5 more
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