Results 41 to 50 of about 1,580,164 (331)

Nanomedicine strategies for central nervous system (CNS) diseases

Frontiers in Biomaterials Science, 2023
The blood-brain barrier (BBB) is a crucial part of brain anatomy as it is a specialized, protective barrier that ensures proper nutrient transport to the brain, ultimately leading to regulating proper brain function.
Shreya Nagri, Olivia Rice, Yupeng Chen
doaj   +1 more source

P2X7 receptor: an emerging target in central nervous system diseases. [PDF]

, 2014
The ATP-sensitive homomeric P2X7 receptor (P2X7R) has received particular attention as a potential drug target because of its widespread involvement in inflammatory diseases as a key regulatory element of the inflammasome complex.
Illes, P., Sperlágh, Beáta
core   +1 more source

Exosomes as cell-derivative carriers in the diagnosis and treatment of central nervous system diseases

Drug Delivery and Translational Research, 2021
Exosomes are extracellular vesicles with the diameter ranging from 50 to 100 nm and are found in different body fluids such as blood, cerebrospinal fluid (CSF), urine and saliva. Like in case of various diseases, based on the parent cells, the content of
Gayatri Gopal Shetgaonkar, Shirleen Miriam Marques, C. E. M. DCruz, R. Vibhavari, L. Kumar, R. Shirodkar   +5 more
semanticscholar   +1 more source

Indukált pluripotens őssejtek szerepe a neurológiai betegségek modellezésében [PDF]

, 2015
The longitudinal follow-up of the development and course of central nervous system related diseases on a molecular level was unsolved for decades. Direct examination of the pathological state on organ or tissue levels was feasible in the late stage of ...
Balogh, Zoltán, Molnár, Mária Judit, Réthelyi, János   +2 more
core   +1 more source

Assessment of Appetite-Regulating Hormones Provides Further Evidence of Altered Adipoinsular Axis in Early Psychosis

Frontiers in Psychiatry, 2020
It has been found that antipsychotic-naïve patients with first-episode psychosis (FEP) present with impaired hormonal regulation of appetite in terms of low leptin and high insulin levels (the adipoinsular axis).
Michał Lis, Bartłomiej Stańczykiewicz, Lilla Pawlik-Sobecka, Agnieszka Samochowiec, Artur Reginia, Błażej Misiak   +5 more
doaj   +1 more source

Evaluating the efficiency of a nomogram based on the data of neurosurgical intensive care unit patients to predict pulmonary infection of multidrug-resistant Acinetobacter baumannii

Frontiers in Cellular and Infection Microbiology, 2023
BackgroundPulmonary infection caused by multidrug-resistant Acinetobacter baumannii (MDR-AB) is a common and serious complication after brain injury. There are no definitive methods for its prediction and it is usually accompanied by a poor prognosis ...
Di Wu, Di Wu, Zhuang Sha, Zhuang Sha, Yibing Fan, Yibing Fan, Jiangyuan Yuan, Jiangyuan Yuan, Weiwei Jiang, Weiwei Jiang, Mingqi Liu, Mingqi Liu, Meng Nie, Meng Nie, Chenrui Wu, Chenrui Wu, Tao Liu, Tao Liu, Yupeng Chen, Yupeng Chen, Jiancheng Feng, Jiancheng Feng, Shiying Dong, Shiying Dong, Jin Li, Jian Sun, Jian Sun, Chongjie Pang, Rongcai Jiang, Rongcai Jiang   +29 more
doaj   +1 more source

Delivering the Promise of Gene Therapy with Nanomedicines in Treating Central Nervous System Diseases

Advancement of science, 2022
Central Nervous System (CNS) diseases, such as Alzheimer's diseases (AD), Parkinson's Diseases (PD), brain tumors, Huntington's disease (HD), and stroke, still remain difficult to treat by the conventional molecular drugs.
Meihua Luo, L. Lee, Bo Peng, C. H. J. Choi, W. Tong, N. Voelcker   +5 more
semanticscholar   +1 more source

Design and construction of a distributed sensor NET for biotelemetric monitoring of brain energetic metabolism using microsensors and biosensors [PDF]

, 2010
Neurochemical pathways involved in brain physiology or disease pathogenesis are mostly unknown either in physiological conditions or in neurodegenerative diseases.
Bazzu, Gianfranco, Calia, Giammario, Migheli, Rossana, Puggioni, Giulia, Rocchitta, Gaia Giovanna Maria, Serra, Pier Andrea   +5 more
core   +2 more sources

PPARα Modulation-Based Therapy in Central Nervous System Diseases

Life, 2021
The burden of neurodegenerative diseases in the central nervous system (CNS) is increasing globally. There are various risk factors for the development and progression of CNS diseases, such as inflammatory responses and metabolic derangements.
Deokho Lee, Yohei Tomita, William Allen, Kazuo Tsubota, Kazuno Negishi, Toshihide Kurihara   +5 more
doaj   +1 more source

Differential in vitro infection of neural cells by astroviruses [PDF]

, 2019
Encephalitis remains a diagnostic conundrum in humans as over 50% of cases are managed without the identification of an etiology. Astroviruses have been detected from the central nervous system of mammals in association with disease, suggesting that this
Janowski, Andrew B, Klein, Robyn S, Wang, David   +2 more
core   +2 more sources