Results 31 to 40 of about 1,580,164 (331)
Role of exosomes in the pathogenesis, diagnosis, and treatment of central nervous system diseases
Journal of Translational Medicine, 2022 Central nervous system (CNS) diseases, such as multiple sclerosis, Alzheimer's disease (AD), and Parkinson’s disease (PD), affect millions of people around the world.
Yishu Fan, Zhuohui Chen, Mengqi Zhang
semanticscholar +1 more source
The Pharmacological Action of Kaempferol in Central Nervous System Diseases: A Review
Frontiers in Pharmacology, 2021 Kaempferol (KPF) is a flavonoid antioxidant found in fruits and vegetables. Many studies have described the beneficial effects of dietary KPF in reducing the risk of chronic diseases, especially cancer.
Jéssica Silva dos Santos +3 more
semanticscholar +1 more source
New Insights into the Roles of p53 in Central Nervous System Diseases
International Journal of Neuropsychopharmacology, 2023 The transcription factor p53, a widely accepted tumor suppressor, regulates the expression of many oncogenes and their downstream signaling pathways, resulting in a series of biological outcomes.
Haili Li +4 more
semanticscholar +1 more source
Neuroprotective Mechanisms of Ginsenoside Rb1 in Central Nervous System Diseases
Frontiers in Pharmacology, 2022 Panax ginseng and Panax notoginseng, two well-known herbs with enormous medical value in Asian countries, have a long usage history in China for the therapy of some diseases, such as stroke.
L. Gong +8 more
semanticscholar +1 more source
Intranasal administration of stem cell-derived exosomes for central nervous system diseases
Neural Regeneration Research, 2023 Exosomes, lipid bilayer-enclosed small cellular vesicles, are actively secreted by various cells and play crucial roles in intercellular communication. These nanosized vesicles transport internalized proteins, mRNA, miRNA, and other bioactive molecules ...
Shuho Gotoh, M. Kawabori, Miki Fujimura
semanticscholar +1 more source
The spleen: a hub connecting nervous and immune systems in cardiovascular and metabolic diseases [PDF]
, 2017 Metabolic disorders have been identified as major health problems affecting a large portion of the world population. In addition, obesity and insulin resistance are principal risk factors for the development of cardiovascular diseases.
Carnevale, Daniela +3 more
core +2 more sources
The Brain-Gut-Microbiome Axis. [PDF]
, 2018 Preclinical and clinical studies have shown bidirectional interactions within the brain-gut-microbiome axis. Gut microbes communicate to the central nervous system through at least 3 parallel and interacting channels involving nervous, endocrine, and ...
Kalani, Amir +3 more
core +2 more sources
The regulatory role of lipophagy in central nervous system diseases
Cell Death Discovery, 2023 Lipid droplets (LDs) are the organelles for storing neutral lipids, which are broken down when energy is insufficient. It has been suggested that excessive accumulation of LDs can affect cellular function, which is important to coordinate homeostasis of ...
Zhu Lan +4 more
semanticscholar +1 more source
Isolated central nervous system Whipple disease
Surgical Neurology International, 2022 Background: Whipple disease (WD) is an infection caused by Tropheryma whipplei, which might present in three different forms: classical, localized, and isolated in the central nervous system (CNS). Methods: We report the result of a systematic review of the literature on WD unusually presenting with exclusively neurological symptoms, including two
Barbero-Aznarez, Pablo +9 more
openaire +3 more sources
Facilitatory actions of guanidine on synaptic transmission in mammalian brain slices [PDF]
, 1979 Guanidine administration may be beneficial in the treatment of amyotrophic lateral sclerosis and related diseases; however, the actions of guanidine on the mammalian central nervous system have not been investigated.
Galvan, Martin +2 more
core +1 more source