Results 91 to 100 of about 6,990,145 (285)
Central Connections Fall 2009 [PDF]
, 2009 Central connections was the free magazine for Central Washington University alumni and friends. In 2019 it was replaced by Crimson and Black.https://digitalcommons.cwu.edu/central_connections/1000/thumbnail ...
Central Washington University
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Multifaceted regulation of thymic tolerance by pattern recognition cascades
Frontiers in ImmunologyDuring their development, progenitor T cells have to pass through a series of tolerogenic filters inside the thymus, which ensure the survival and developmental advancement of only those thymocytes which fruitfully recognize the host’s own MHCs ...
Soumyadeep Mukherjee +3 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Central Connections Fall 2018 [PDF]
, 2018 Central connections was the free magazine for Central Washington University alumni and friends. In 2019 it was replaced by Crimson and Black.https://digitalcommons.cwu.edu/central_connections/1003/thumbnail ...
Central Washington University
core +1 more source
Evaluating in vivo approaches for studying the roles of thymic DCs in T cell development in mice
Frontiers in ImmunologyT cells express an enormous repertoire of T cell receptors, enabling them to recognize any potential antigen. This large repertoire undergoes stringent selections in the thymus, where receptors that react to self- or non-danger-associated- antigens are ...
Yi Wang +3 more
doaj +1 more source
Central African Republic [cartographic material].
, 2001 "Base 802738 (B01340) 2-01"; Map of Central African Republic showing international and prefecture boundaries, national and prefecture capitals, railroads, and roads.; Also available online http://nla.gov.au/nla.map ...
United States. Central Intelligence Agency.
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Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
T-cell tolerance and autoimmunity in transgenic models of central and peripheral tolerance
Current Opinion in Immunology, 1994 Experiments with transgenic mice expressing genes encoding both antigens in defined tissues and T-cell receptor genes of known specificities have enhanced our understanding of the mechanisms involved in the pathogenesis of autoimmune states. They have also shed light on the means by which potentially autoreactive cells may be prevented from exerting ...
J F, Miller, R A, Flavell
openaire +2 more sources
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Central Connections Fall 2013 [PDF]
, 2013 Central connections was the free magazine for Central Washington University alumni and friends. In 2019 it was replaced by Crimson and Black.https://digitalcommons.cwu.edu/central_connections/1001/thumbnail ...
Central Washington University
core +1 more source