Results 131 to 140 of about 27,287 (301)

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

Experimental Physiology, EarlyView.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base [PDF]

, 2014
The transition zone (TZ) is a specialized compartment found at the base of cilia, adjacent to the centriole distal end, where axonemal microtubules (MTs) are heavily cross-linked to the surrounding membrane to form a barrier that gates the ciliary ...
Amack, Jeffrey D., Asara, John M., Goll, Mary G., Macaluso, Frank P., Perumal, Geoffrey S., Soni, Rajesh, Tay, Hwee Goon, Tsou, Meng-Fu Bryan, Wang, Won-Jing   +8 more
core   +1 more source

Cep57 and Cep57l1 function redundantly to recruit the Cep63–Cep152 complex for centriole biogenesis

Journal of Cell Science, 2020
The Cep63–Cep152 complex located at the mother centriole recruits Plk4 to initiate centriole biogenesis. How the complex is targeted to mother centrioles, however, is unclear.
Huijie Zhao, Sen Yang, Qingxia Chen, Xiaomeng Duan, Guoqing Li, Qiongping Huang, Xueliang Zhu, Xiumin Yan   +7 more
semanticscholar   +1 more source

The absence of both RIBC1 and RIBC2 induces decreased sperm motility and litter size in male mice

Andrology, Volume 14, Issue 2, Page 545-554, February 2026.
Abstract Background RIBC1 (RIB43A domain with coiled‐coils 1) and RIBC2 (RIB43A domain with coiled‐coils 2) are homolog proteins of RIB43a which is localized to microtubules in the cilia and flagella of unicellular organisms. Cryo‐electron microscopy and artificial intelligence studies showed that RIBC1 and RIBC2 are microtubule inner proteins (MIPs ...
Kento Katsuma, Keisuke Shimada, Shingo Tonai, Daisuke Mashiko, Rie Iida‐Norita, Yuki Kaneda, Haruhiko Miyata, Masahito Ikawa   +7 more
wiley   +1 more source

A role for Separase in telomere protection [PDF]

, 2016
Drosophila telomeres are elongated by transposition of specialized retroelements rather than telomerase activity and are assembled independently of the sequence. Fly telomeres are protected by the terminin complex that localizes and functions exclusively
Bosso, Giuseppe, Cacchione, Stefano, Cenci, Giovanni, Cipressa, Francesca, Galati, Alessandra, Grazia Daniela, Mannini, Linda, Morciano, Patrizia, Musio, Antonio, Raffa   +9 more
core   +1 more source

Missense Variants in the Second Transmembrane Domain of TMEM17 Disrupt Its Stability and Function and Lead to a Wide Phenotypic Spectrum of Ciliopathies

Clinical Genetics, Volume 109, Issue 2, Page 305-315, February 2026.
Missense variants in TMEM17 disrupt its localization and function at the ciliary transition zone, leading to a wide range of ciliopathy phenotypes, from OFD6 and Joubert syndromes to Meckel syndrome. ABSTRACT Ciliopathies are rare genetic disorders characterized by significant genetic and phenotypic variability.
Lucile Boutaud, Chunmei Li, Candice Moncler, Laure Verlin, Meriem Garfa‐Traoré, Nicolas Bourgon, Dhruvin Akbari, Jeanne Porée, Valentina Serpieri, Marine Panza, Lynda Haddad, Patrick Nitschké, Jacqueline Aziza, Cristina Matt, Enza Maria Valente, Patricia Gargallo, Charlotte Dubucs, Tania Attié‐Bitach, Michel R. Leroux, Sophie Thomas   +19 more
wiley   +1 more source

PPP1R35 is a novel centrosomal protein that regulates centriole length in concert with the microcephaly protein RTTN

eLife, 2018
Centrosome structure, function, and number are finely regulated at the cellular level to ensure normal mammalian development. Here, we characterize PPP1R35 as a novel bona fide centrosomal protein and demonstrate that it is critical for centriole ...
Andrew Michael Sydor, Etienne Coyaud, Cristina Rovelli, Estelle Laurent, Helen Liu, Brian Raught, Vito Mennella   +6 more
doaj   +1 more source

Dynamic centriolar localization of Polo and Centrobin in early mitosis primes centrosome asymmetry.

PLoS Biology, 2020
Centrosomes, the main microtubule organizing centers (MTOCs) of metazoan cells, contain an older "mother" and a younger "daughter" centriole. Stem cells either inherit the mother or daughter-centriole-containing centrosome, providing a possible mechanism
Emmanuel Gallaud, Anjana Ramdas Nair, Nicole Horsley, Arnaud Monnard, Priyanka Singh, Tri Thanh Pham, David Salvador Garcia, Alexia Ferrand, Clemens Cabernard   +8 more
doaj   +1 more source

Role of Centriolar Matrix and Striated Rootlets in Centriolar Pairing and Orientation During Spermatogenesis in Hydractina echinata [PDF]

, 1985
Transmission electron microscopy of the spermatogenic stages of the hydroid, Hydractinia echinata, reveals a series of complex structural and positional changes in the centrioles of spermatocytes and spermatids.
Kleve, Maurice G.
core   +2 more sources

C-Nap1 mutation affects centriole cohesion and is associated with a Seckel-like syndrome in cattle [PDF]

, 2015
Caprine-like Generalized Hypoplasia Syndrome (SHGC) is an autosomal-recessive disorder in Montbéliarde cattle. Affected animals present a wide range of clinical features that include the following: delayed development with low birth weight, hind limb ...
Barbey, Sarah, Bertaud, Maud, Boichard, Didier, Bourgain-Guglielmetti, Florence, Cesbron, Nora, Cormier-Daire, Valérie, Duchesne, Amandine, E L Hokayem, Joyce, Eggen, Andre, Floriot, Sandrine, Fritz, Sebastien, Gautier, Mathieu, Guatteo, Raphaël, Halliez, Sophie, Karaiskou, Anthi, Manciaux, Luc, Moudjou, Mohammed, Nigg, Erich A, Rodriguez, Sabrina, Schibler, Laurent, Schneider-Maunoury, Sylvie, Sobczak-Thépot, Joelle, Toutirais, Geraldine, Vasilescu, Alexandre, Vesque, Christine   +24 more
core   +4 more sources