Results 21 to 30 of about 19,940 (252)

Atypical centrioles are present in Tribolium sperm [PDF]

Open Biology, 2017
Typical centrioles are made of microtubules organized in ninefold symmetry. Most animal somatic cells have two centrioles for normal cell division and function.
E. L. Fishman, Kyoung Jo, Andrew Ha, Rachel Royfman, Ashtyn Zinn, Malathi Krishnamurthy, Tomer Avidor-Reiss   +6 more
doaj   +1 more source

Flies without Centrioles [PDF]

Cell, 2006
Centrioles and centrosomes have an important role in animal cell organization, but it is uncertain to what extent they are essential for animal development. The Drosophila protein DSas-4 is related to the human microcephaly protein CenpJ and the C. elegans centriolar protein Sas-4.
C. Geoffrey Woods, Joyce Lau, Tatiana Vinogradova, Tatiana Vinogradova, Alejandra Gardiol, Jordan W. Raff, Alexey Khodjakov, Alexey Khodjakov, Renata Basto   +8 more
openaire   +4 more sources

Functional Analysis of Hydrolethalus Syndrome Protein HYLS1 in Ciliogenesis and Spermatogenesis in Drosophila

Frontiers in Cell and Developmental Biology, 2020
Cilia and flagella are conserved subcellular organelles, which arise from centrioles and play critical roles in development and reproduction of eukaryotes. Dysfunction of cilia leads to life-threatening ciliopathies.
Yanan Hou, Zhimao Wu, Zhimao Wu, Zhimao Wu, Yingying Zhang, Yingying Zhang, Yingying Zhang, Huicheng Chen, Huicheng Chen, Huicheng Chen, Jinghua Hu, Yi Guo, Ying Peng, Ying Peng, Qing Wei   +14 more
doaj   +1 more source

Overview of the centriole architecture

Current Opinion in Structural Biology, 2021
The centriole is a magnificent molecular assembly of several giga-daltons, one of the largest of the eukaryotic cell, and whose atomic structure remains unsolved to date. However, numerous electron microscopy, cryo-tomography, and super-resolution studies now make it possible to establish a global architectural view of it with its different sub-regions.
LeGuennec, Maeva, Klena, Nikolai, Aeschlimann, Gabriel, Hamel, Virginie, Guichard, Paul   +4 more
openaire   +3 more sources

Centriole assembly at a glance [PDF]

Journal of Cell Science, 2019
ABSTRACT The centriole organelle consists of microtubules (MTs) that exhibit a striking 9-fold radial symmetry. Centrioles play fundamental roles across eukaryotes, notably in cell signaling, motility and division. In this Cell Science at a Glance article and accompanying poster, we cover the cellular life cycle of this organelle – from ...
Pierre Gönczy, Georgios N. Hatzopoulos
openaire   +2 more sources

Rapid Evolution of Sperm Produces Diverse Centriole Structures that Reveal the Most Rudimentary Structure Needed for Function

Cells, 2018
Centrioles are ancient subcellular protein-based organelles that maintain a conserved number and structure across many groups of eukaryotes. Centriole number (two per cells) is tightly regulated; each pre-existing centriole nucleates only one centriole ...
Tomer Avidor-Reiss
doaj   +1 more source

A novel Cep120-dependent mechanism inhibits centriole maturation in quiescent cells [PDF]

, 2018
The two centrioles of the centrosome in quiescent cells are inherently asymmetric structures that differ in age, morphology and function. How these asymmetric properties are established and maintained during quiescence remains unknown. Here, we show that
Betleja, Ewelina, Cheng, Tao, Mahjoub, Moe R, Nanjundappa, Rashmi   +3 more
core   +2 more sources

Pericentrin-mediated SAS-6 recruitment promotes centriole assembly

eLife, 2019
The centrosome is composed of two centrioles surrounded by a microtubule-nucleating pericentriolar material (PCM). Although centrioles are known to regulate PCM assembly, it is less known whether and how the PCM contributes to centriole assembly. Here we
Daisuke Ito, Sihem Zitouni, Swadhin Chandra Jana, Paulo Duarte, Jaroslaw Surkont, Zita Carvalho-Santos, José B Pereira-Leal, Miguel Godinho Ferreira, Mónica Bettencourt-Dias   +8 more
doaj   +1 more source

Protein Phosphatase 1 Down Regulates ZYG-1 Levels to Limit Centriole Duplication. [PDF]

PLoS Genetics, 2017
In humans perturbations of centriole number are associated with tumorigenesis and microcephaly, therefore appropriate regulation of centriole duplication is critical. The C.
Nina Peel, Jyoti Iyer, Anar Naik, Michael P Dougherty, Markus Decker, Kevin F O'Connell   +5 more
doaj   +1 more source

Basal body stability and ciliogenesis requires the conserved component Poc1 [PDF]

, 2009
Centrioles are the foundation for centrosome and cilia formation. The biogenesis of centrioles is initiated by an assembly mechanism that first synthesizes the ninefold symmetrical cartwheel and subsequently leads to a stable cylindrical microtubule ...
Abal, Andersen, Avidor-Reiss, Azimzadeh, Badano, Bakowska, Balczon, Baron, Basmussen, Basto, Beisson, Berbari, Blachon, Bobinnec, Bobinnec, Broadhead, Brown, Bruns, Chad G. Pearson, Cheeseman, Culver, Dammermann, Dammermann, Daniel P.S. Osborn, Dupuis-Williams, Dutcher, Dutcher, Dutcher, Eddé, Eggenschwiler, Essner, Fry, Gaertig, Garreau de Loubresse, Gerdes, Graser, Gundersen, Hai, Hames, Hentschel, Hildebrandt, Hiraki, Jerka-Dziadosz, Kaczanowski, Keller, Keller, Kilburn, Kirkham, Kochanski, Le Clech, Leidel, Leidel, Leidel, Li, Liu, Mark Winey, Marshall, Marshall, Martinez-Campos, Matsuura, Million, Mottier-Pavie, Nakazawa, Nanney, Neuhauss, Orias, Paoletti, Pearson, Pearson, Pelletier, Peterkin, Philip L. Beales, Piperno, Rodrigues-Martins, Salisbury, Shang, Shang, Stemm-Wolf, Strnad, Thomas H. Giddings, Tobin, Tobin, Vladar, Westerfield, Wilkinson, Williams, Wloga, Woodland   +87 more
core   +2 more sources