Results 21 to 30 of about 27,287 (301)
Structure and function of distal and subdistal appendages of the mother centriole.
Journal of Cell Science, 2023 Centrosomes are composed of centrioles surrounded by pericentriolar material. The two centrioles in G1 phase are distinguished by the localization of their appendages in the distal and subdistal regions; the centriole possessing both types of appendage ...
Dandan Ma +4 more
semanticscholar +1 more source
EMBO Journal, 2023 In most metazoans, centrioles are lost during oogenesis, ensuring that the zygote is endowed with the correct number of two centrioles, which are paternally contributed. How centriole architecture is dismantled during oogenesis is not understood.
M. Pierron +6 more
semanticscholar +1 more source
The evolution of centriole degradation in mouse sperm
bioRxiv, 2023 Centrioles have a conserved structure and function but have diversified in sperm. Here the authors provide insight into the molecular mechanisms and adaptive evolution underlying this diversification.
Sushil Khanal +15 more
semanticscholar +1 more source
Integrity of the Pericentriolar Material Is Essential for Maintaining Centriole Association during M Phase. [PDF]
PLoS ONE, 2015 A procentriole is assembled next to the mother centriole during S phase and remains associated until M phase. After functioning as a spindle pole during mitosis, the mother centriole and procentriole are separated at the end of mitosis.
Mi Young Seo, Wonyul Jang, Kunsoo Rhee
doaj +1 more source
Molecular architecture of the C. elegans centriole
bioRxiv, 2022 Uncovering organizing principles of organelle assembly is a fundamental pursuit in the life sciences. C. elegans was key in identifying evolutionary conserved components governing assembly of the centriole organelle.
Alexander Woglar +5 more
semanticscholar +1 more source
Human SFI1 and Centrin form a complex critical for centriole architecture and ciliogenesis
EMBO Journal, 2022 Over the course of evolution, the centrosome function has been conserved in most eukaryotes, but its core architecture has evolved differently in some clades, with the presence of centrioles in humans and a spindle pole body (SPB) in yeast.
Marine. H. Laporte +10 more
semanticscholar +1 more source
Experimental and Natural Induction of de novo Centriole Formation
Frontiers in Cell and Developmental Biology, 2022 In cycling cells, new centrioles are assembled in the vicinity of pre-existing centrioles. Although this canonical centriole duplication is a tightly regulated process in animal cells, centrioles can also form in the absence of pre-existing centrioles ...
Kasuga Takumi, Daiju Kitagawa
doaj +1 more source
The central scaffold protein CEP350 coordinates centriole length, stability, and maturation
Journal of Cell Biology, 2022 Karasu et al. aim to shed light on mechanisms of how the length and structural integrity of centrioles, which are stable microtubule-based structures, are ensured.
O. Karasu +4 more
semanticscholar +1 more source
CDK11(p58) is required for centriole duplication and Plk4 recruitment to mitotic centrosomes. [PDF]
PLoS ONE, 2011 BACKGROUND: CDK11(p58) is a mitotic protein kinase, which has been shown to be required for different mitotic events such as centrosome maturation, chromatid cohesion and cytokinesis.
Nathalie Franck +5 more
doaj +1 more source
Superresolution characterization of core centriole architecture
Journal of Cell Biology, 2021 Proteins within the core region of the centriole remain challenging to be resolved in vivo. Tian et al. present a spatiotemporal map of the centriole core and implications of how the proteins might interact to build the ninefold symmetrical centriole.
Yuan Tian +7 more
semanticscholar +1 more source