Results 21 to 30 of about 20,027 (280)
Atypical centrioles are present in Tribolium sperm [PDF]
Open Biology, 2017 Typical centrioles are made of microtubules organized in ninefold symmetry. Most animal somatic cells have two centrioles for normal cell division and function.
E. L. Fishman +6 more
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Protein Phosphatase 1 Down Regulates ZYG-1 Levels to Limit Centriole Duplication. [PDF]
PLoS Genetics, 2017 In humans perturbations of centriole number are associated with tumorigenesis and microcephaly, therefore appropriate regulation of centriole duplication is critical. The C.
Nina Peel +5 more
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A role for Gle1, a regulator of DEAD-box RNA helicases, at centrosomes and basal bodies. [PDF]
, 2017 Control of organellar assembly and function is critical to eukaryotic homeostasis and survival. Gle1 is a highly conserved regulator of RNA-dependent DEAD-box ATPase proteins, with critical roles in both mRNA export and translation.
Akef, Abdalla +2 more
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Centriole assembly at a glance [PDF]
Journal of Cell Science, 2019 ABSTRACT The centriole organelle consists of microtubules (MTs) that exhibit a striking 9-fold radial symmetry. Centrioles play fundamental roles across eukaryotes, notably in cell signaling, motility and division. In this Cell Science at a Glance article and accompanying poster, we cover the cellular life cycle of this organelle – from ...
Pierre Gönczy, Georgios N. Hatzopoulos
openaire +2 more sources
Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity [PDF]
, 2007 Faithful chromosome segregation in mitosis requires the formation of a bipolar mitotic spindle with stably attached chromosomes. Once all of the chromosomes are aligned, the connection between the sister chromatids is severed by the cysteine protease ...
Gruneberg, Ulrike +3 more
core +3 more sources
Cell Reports, 2016 PLK4 is the major kinase driving centriole duplication. Duplication occurs only once per cell cycle, forming one new (or daughter) centriole that is tightly engaged to the preexisting (or mother) centriole.
Minhee Kim +5 more
doaj +1 more source
Basal body stability and ciliogenesis requires the conserved component Poc1 [PDF]
, 2009 Centrioles are the foundation for centrosome and cilia formation. The biogenesis of centrioles is initiated by an assembly mechanism that first synthesizes the ninefold symmetrical cartwheel and subsequently leads to a stable cylindrical microtubule ...
Abal +87 more
core +2 more sources
The interrelationship between APC/C and Plk1 activities in centriole disengagement
Biology Open, 2012 Summary Mother–daughter centriole disengagement, the necessary first step in centriole duplication, involves Plk1 activity in early mitosis and separase activity after APC/C activity mediates securin degradation.
Toshiyuki Hatano, Greenfield Sluder
doaj +1 more source
Three-dimensional structure of basal body triplet revealed by electron cryo-tomography. [PDF]
, 2011 Basal bodies and centrioles play central roles in microtubule (MT)-organizing centres within many eukaryotes. They share a barrel-shaped cylindrical structure composed of nine MT triplet blades.
Agard, David A +3 more
core +2 more sources
Pericentrin-mediated SAS-6 recruitment promotes centriole assembly
eLife, 2019 The centrosome is composed of two centrioles surrounded by a microtubule-nucleating pericentriolar material (PCM). Although centrioles are known to regulate PCM assembly, it is less known whether and how the PCM contributes to centriole assembly. Here we
Daisuke Ito +8 more
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