Results 31 to 40 of about 18,948 (224)
The ciliary GTPase Arl13b regulates cell migration and cell cycle progression [PDF]
, 2016 Acknowledgments We acknowledge Prof. Tamara Caspary from Emory University for kindly providing the cell lines, Linda Duncan from the University of Aberdeen Ian Fraser Cytometry Center for help with flow cytometry.
Clancy, Hannah +6 more
core +2 more sources
Frontiers in Molecular Biosciences, 2023 Primary cilia from the brain microvascular endothelial cells (ECs) are specialized cell-surface organelles involved in mediating sensory perception, cell signaling, and vascular stability.
Karthikeyan Thirugnanam +6 more
doaj +1 more source
A role for Gle1, a regulator of DEAD-box RNA helicases, at centrosomes and basal bodies. [PDF]
, 2017 Control of organellar assembly and function is critical to eukaryotic homeostasis and survival. Gle1 is a highly conserved regulator of RNA-dependent DEAD-box ATPase proteins, with critical roles in both mRNA export and translation.
Akef, Abdalla +2 more
core +1 more source
eLife, 2020 Directional sensitivity of hair cells (HCs) is conferred by the aymmetric apical hair bundle, comprised of a kinocilium and stereocilia staircase. The mother centriole (MC) forms the base of the kinocilium and the stereocilia develop adjacent to it ...
Yosuke Tona, Doris K Wu
doaj +1 more source
Current Opinion in Cell Biology, 2013 Centrioles are the key foundation of centrosomes and cilia, yet a molecular understanding of how they form has only recently begun to emerge. Building a fully functional centriole that can form a centrosome and cilium requires two cell cycles. Centriole building starts with procentriole nucleation, a process that is coordinated by the conserved ...
Tomer, Avidor-Reiss +1 more
openaire +2 more sources
The E2F-DP1 Transcription Factor Complex Regulates Centriole Duplication in Caenorhabditis elegans
G3: Genes, Genomes, Genetics, 2016 Centrioles play critical roles in the organization of microtubule-based structures, from the mitotic spindle to cilia and flagella. In order to properly execute their various functions, centrioles are subjected to stringent copy number control.
Jacqueline G. Miller +4 more
doaj +1 more source
Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity [PDF]
, 2020 The red-crowned crane (Grus japonensis) is an endangered, large-bodied crane native to East Asia. It is a traditional symbol of longevity and its long lifespan has been confirmed both in captivity and in the wild.
Bhak, Jong +14 more
core +1 more source
Generation and Characterization of a Tissue-Specific Centrosome Indicator Mouse Line. [PDF]
, 2016 Centrosomes are major microtubule organizing centers (MTOCs) that play an important role in chromosome segregation during cell division. Centrosomes provide a stable anchor for microtubules, constituting the centers of the spindle poles in mitotic cells,
Chen, Ju +2 more
core +2 more sources
The Drosophila Citrate Lyase Is Required for Cell Division during Spermatogenesis [PDF]
, 2020 The Drosophila melanogaster DmATPCL gene encodes for the human ATP Citrate Lyase (ACL) ortholog, a metabolic enzyme that from citrate generates glucose-derived Acetyl-CoA, which fuels central biochemical reactions such as the synthesis of fatty acids ...
Bucciarelli, Elisabetta +8 more
core +1 more source
Current Biology, 2010 Centrioles are conserved microtubule-based organelles that lie at the core of the animal centrosome and play a crucial role in nucleating the formation of cilia and flagella in most eukaryotes. Centrioles have a complex ultrastructure with ninefold symmetry and a well-defined length.
Azimzadeh, Juliette +1 more
openaire +2 more sources