Results 51 to 60 of about 13,342 (208)

Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity [PDF]

, 2007
Faithful chromosome segregation in mitosis requires the formation of a bipolar mitotic spindle with stably attached chromosomes. Once all of the chromosomes are aligned, the connection between the sister chromatids is severed by the cysteine protease ...
Erich A. Nigg, Kleylein-Sohn, J, Nigg, EA, Thein, Kerstin H., Kerstin H. Thein, Gruneberg, Ulrike, Nigg, E. A., Grueneberg, U., Julia Kleylein-Sohn, Thein, KH, Kleylein-Sohn, Julia, Kleylein-Sohn, J., Ulrike Gruneberg, Nigg, Erich A., Thein, K. H.   +14 more
core   +1 more source

Regulation of cilia abundance in multiciliated cells

eLife, 2019
Multiciliated cells (MCC) contain hundreds of motile cilia used to propel fluid over their surface. To template these cilia, each MCC produces between 100-600 centrioles by a process termed centriole amplification.
Rashmi Nanjundappa, Dong Kong, Kyuhwan Shim, Tim Stearns, Steven L Brody, Jadranka Loncarek, Moe R Mahjoub   +6 more
doaj   +1 more source

The Life Cycle of Centrioles [PDF]

Cold Spring Harbor Symposia on Quantitative Biology, 2010
Centrioles organize the centrosome and nucleate the ciliary axoneme, and the centriole life cycle has many parallels to the chromosome cycle. The centriole cycle in animals begins at fertilization with the contribution of two centrioles by the male gamete.
E, Hatch, T, Stearns
openaire   +2 more sources

Computational support for a scaffolding mechanism of centriole assembly [PDF]

, 2016
Centrioles are essential for forming cilia, flagella and centrosomes. Successful centriole assembly requires proteins of the SAS-6 family, which can form oligomeric ring structures with ninefold symmetry in vitro.
Klein, Heinrich C. R., Guichard, Paul, Hamel, Virginie, Schwarz, Ulrich S., Gönczy, Pierre   +4 more
core   +2 more sources

Over-elongation of centrioles in cancer promotes centriole amplification and chromosome missegregation [PDF]

, 2018
This deposit is composed by the main article plus the supplementary materials of the publication.Centrosomes are the major microtubule organising centres of animal cells.
Barbosa-Morais N, Mesquita M, Dores K, Godinho, S, Fonseca, I, De Almeida B, Mesquita, Marta, Bernardo P. de Almeida, Vieira, Andre F., Marteil G, Pellman D, Godinho, Susana, Barbosa-Morais, Nuno L., Susana Mendonça, Jana S, Vieira, André, Martins, N, Barbosa-Morais, Nuno, Adan Guerrero, Villarreal B, Mesquita, M, Barbosa-Morais, NL, Francia M, Martins N, Barbosa-Morais, Nuno L, Vieira, André F, Vieira, AF, Machado, P, Bettencourt-Dias, Mónica, Jana, Swadhin C., Francia, Maria, Guerrero, Adan, Bettencourt-Dias, M, Beth Villarreal, Maria E. Francia, Marteil, Gaëlle, Godinho, Susana A., Paredes, J, Mendonça, Susana, Marteil, G, Nuno L. Barbosa-Morais, Pedro Machado, Jana, SC, Paredes J, Fonseca I, Martins, Nuno, de Almeida, Bernardo P., Francia, ME, Guerrero A, Godinho S, Tranfield, EM, Machado P, Vieira AF, Tranfield, Erin, Paredes, Joana, Villarreal, B, Jana, S, Jana, Swadhin C, Gaëlle Marteil, Guerrero, A, Tranfield, E, Pellman, David, Francia, Maria E., Irina Fonseca, Joana Paredes, Francia, M, Francia, Maria E, Villarreal, Beth, de Almeida, Bernardo, Tranfield, Erin M, Fonseca, Irina, de Almeida, Bernardo P, Katharina Dores, Martins, NP, Erin M. Tranfield, de Almeida, BP, Machado, Pedro, Bettencourt-Dias M, Martins, Nuno P., Dores, K, Mónica Bettencourt-Dias, Pellman, D, Marta Mesquita, Mendonca, S, Almeida, B, André F. Vieira, David Pellman, Jana, Swadhin, Nuno P. Martins, Swadhin C. Jana, Tranfield, Erin M., Susana A. Godinho, Tranfield E, Dores, Katharina, Mendonça S, Martins, Nuno P, Godinho, SA, Godinho, Susana A, Barbosa-Morais, N   +98 more
core   +1 more source

A helical inner scaffold provides a structural basis for centriole cohesion. [PDF]

, 2020
The ninefold radial arrangement of microtubule triplets (MTTs) is the hallmark of the centriole, a conserved organelle crucial for the formation of centrosomes and cilia.
Borgers, Susanne, Kovacik, Lubomir, Gambarotto, D., Laporte, M.H., Engel, B.D., Guichard, Paul, Engel, Benjamin D., Azimzadeh, Juliette, Klena, N., Hoek, Hugo, van Den, Guichard, P., Stahlberg, Henning, Goldie, Kenneth N., Borgers, S., Erdmann, P., Le Guennec, Maeva, Gambarotto, Davide, Tassin, Anne-Marie, Hamel, Virginie, Bornens, Michel, Goldie, K., Schaffer, Miroslava, Hamel, V., Goldie, K.N., Le Guennec, M., Klena, Nikolai, Bornens, M., Laporte, Marine H., Laporte, M., Kovacik, L., Erdmann, Philipp S., Stahlberg, H., Engel, B., van den Hoek, Hugo, Laporte, Marine, van den Hoek, H., Tassin, A.M., Erdmann, P.S., Tassin, A., Schaffer, M., Azimzadeh, J.   +40 more
core   +1 more source

Ciliary Membrane Lipid Homeostasis in Health and Disease

Advanced Science, EarlyView.
This review systematically delineates the distinct lipid landscapes of ciliary membranes, including the spatial organization of phosphoinositides, cholesterol, and sphingolipids. It elucidates how these lipids orchestrate ciliogenesis, signal transduction, and membrane dynamics in cilia beating, and highlights how their dysregulation drives ...
Zhenzhou Huang, Yuan‐yuan Liu, Hanqi Sun, Peiwei Liu   +3 more
wiley   +1 more source

Evolution of centriole assembly [PDF]

Current Biology, 2020
In this Primer, Nabais et al. discuss the evolution of the structure and function of centrioles and basal bodies, describe conserved centriole assembly features and the diversity in centriole architecture across eukaryotes, and highlight important outstanding evolutionary questions concerning centriole assembly.
Catarina, Nabais, Catarina, Peneda, Mónica, Bettencourt-Dias   +2 more
openaire   +2 more sources

Re-examining the role of Drosophila Sas-4 in centrosome assembly using two-colour-3D-SIM FRAP

eLife, 2015
Centrosomes have many important functions and comprise a ‘mother’ and ‘daughter’ centriole surrounded by pericentriolar material (PCM). The mother centriole recruits and organises the PCM and templates the formation of the daughter centriole. It has been
Paul T Conduit, Alan Wainman, Zsofia A Novak, Timothy T Weil, Jordan W Raff   +4 more
doaj   +1 more source

Male reproductive system in stenopodidean shrimps: Unveiling basal reproductive traits in shrimp‐like Pleocyemata (Stenopodidae and Spongicolidae)

The Anatomical Record, EarlyView.
Abstract Stenopodidea represents one of the basal lineages within Pleocyemata, yet the male reproductive system (MRS) of this group remains poorly understood, with limited information available regarding its morphology and function. This study provides the first detailed description of the MRS in four stenopodidean shrimp species from two families ...
Caio Santos Nogueira, Lucas Rezende Penido Paschoal, Fernando José Zara   +2 more
wiley   +1 more source