Results 41 to 50 of about 27,287 (301)

Basal body stability and ciliogenesis requires the conserved component Poc1 [PDF]

, 2009
Centrioles are the foundation for centrosome and cilia formation. The biogenesis of centrioles is initiated by an assembly mechanism that first synthesizes the ninefold symmetrical cartwheel and subsequently leads to a stable cylindrical microtubule ...
Abal, Andersen, Avidor-Reiss, Azimzadeh, Badano, Bakowska, Balczon, Baron, Basmussen, Basto, Beisson, Berbari, Blachon, Bobinnec, Bobinnec, Broadhead, Brown, Bruns, Chad G. Pearson, Cheeseman, Culver, Dammermann, Dammermann, Daniel P.S. Osborn, Dupuis-Williams, Dutcher, Dutcher, Dutcher, Eddé, Eggenschwiler, Essner, Fry, Gaertig, Garreau de Loubresse, Gerdes, Graser, Gundersen, Hai, Hames, Hentschel, Hildebrandt, Hiraki, Jerka-Dziadosz, Kaczanowski, Keller, Keller, Kilburn, Kirkham, Kochanski, Le Clech, Leidel, Leidel, Leidel, Li, Liu, Mark Winey, Marshall, Marshall, Martinez-Campos, Matsuura, Million, Mottier-Pavie, Nakazawa, Nanney, Neuhauss, Orias, Paoletti, Pearson, Pearson, Pelletier, Peterkin, Philip L. Beales, Piperno, Rodrigues-Martins, Salisbury, Shang, Shang, Stemm-Wolf, Strnad, Thomas H. Giddings, Tobin, Tobin, Vladar, Westerfield, Wilkinson, Williams, Wloga, Woodland   +87 more
core   +2 more sources

Cep57 and Cep57L1 maintain centriole engagement in interphase to ensure centriole duplication cycle

Journal of Cell Biology, 2021
Ito et al. revealed that centrosomal proteins Cep57 and Cep57L1 cooperatively maintain centriole engagement during interphase in human cells. Codepletion of Cep57 and Cep57L1 induces precocious centriole disengagement in interphase, which results in ...
Kei Ito, Koki Watanabe, Haruki Ishida, Kyohei Matsuhashi, Takumi Chinen, S. Hata, Daiju Kitagawa   +6 more
semanticscholar   +1 more source

Centriole evolution [PDF]

Current Opinion in Cell Biology, 2009
Centrioles are cylindrical structures found at the core of the mitotic spindle pole, which also act as basal bodies to nucleate the formation of cilia. Centrioles have a complex, ninefold symmetric structure, and reproduce by an intriguing duplication process. The complexity and apparent self-reproduction of centrioles raises the question of how such a
openaire   +2 more sources

Promotion and Suppression of Centriole Duplication Are Catalytically Coupled through PLK4 to Ensure Centriole Homeostasis

Cell Reports, 2016
PLK4 is the major kinase driving centriole duplication. Duplication occurs only once per cell cycle, forming one new (or daughter) centriole that is tightly engaged to the preexisting (or mother) centriole.
Minhee Kim, Brian P. O’Rourke, Rajesh Kumar Soni, Prasad V. Jallepalli, Ronald C. Hendrickson, Meng-Fu Bryan Tsou   +5 more
doaj   +1 more source

A delta-tubulin/epsilon-tubulin/Ted protein complex is required for centriole architecture. [PDF]

Elife
Pudlowski R, Xu L, Milenkovic L, Kumar C, Hemsworth K, Aqrabawi Z, Stearns T, Wang JT.   +7 more
europepmc   +2 more sources

Three-dimensional structure of basal body triplet revealed by electron cryo-tomography. [PDF]

, 2011
Basal bodies and centrioles play central roles in microtubule (MT)-organizing centres within many eukaryotes. They share a barrel-shaped cylindrical structure composed of nine MT triplet blades.
Agard, David A, Fernandez, Jose-Jesus, Li, Sam, Marshall, Wallace F   +3 more
core   +2 more sources

Fluorescence-Based Ratiometric Analysis of Sperm Centrioles (FRAC) Finds Patient Age and Sperm Morphology Are Associated With Centriole Quality

Frontiers in Cell and Developmental Biology, 2021
A large proportion of infertility and miscarriage causes are unknown. One potential cause is a defective sperm centriole, a subcellular structure essential for sperm motility and embryonic development.
Katerina A Turner, E. L. Fishman, Mariam Asadullah, Brooke Ott, P. Dusza, Tariq A. Shah, Puneet Sindhwani, N. Nadiminty, E. Molinari, P. Patrizio, Barbara Saltzman, T. Avidor-Reiss   +11 more
semanticscholar   +1 more source

The interrelationship between APC/C and Plk1 activities in centriole disengagement

Biology Open, 2012
Summary Mother–daughter centriole disengagement, the necessary first step in centriole duplication, involves Plk1 activity in early mitosis and separase activity after APC/C activity mediates securin degradation.
Toshiyuki Hatano, Greenfield Sluder
doaj   +1 more source

Protein Phosphatase 1 Down Regulates ZYG-1 Levels to Limit Centriole Duplication. [PDF]

PLoS Genetics, 2017
In humans perturbations of centriole number are associated with tumorigenesis and microcephaly, therefore appropriate regulation of centriole duplication is critical. The C.
Nina Peel, Jyoti Iyer, Anar Naik, Michael P Dougherty, Markus Decker, Kevin F O'Connell   +5 more
doaj   +1 more source

Generation and Characterization of a Tissue-Specific Centrosome Indicator Mouse Line. [PDF]

, 2016
Centrosomes are major microtubule organizing centers (MTOCs) that play an important role in chromosome segregation during cell division. Centrosomes provide a stable anchor for microtubules, constituting the centers of the spindle poles in mitotic cells,
Chen, Ju, Evans, Sylvia M, Hirai, Maretoshi   +2 more
core   +2 more sources