Results 81 to 90 of about 19,940 (252)

Aging‐Associated Vacuolation of Multi‐Ciliated Cells in the Distal Mouse Oviduct Reflects Unique Cell Identity and Luminal Microenvironment

Aging Cell, EarlyView.
Multi‐ciliated cells in the infundibulum and ampulla (INF/AMP) epithelium are vacuolated in aging. Unique cellular susceptibility of the INF/AMP epithelial population and aging‐associated decline in ovarian artery circulation, which supports the ovary and INF/AMP, contribute to this region‐specific vacuolation phenotype, as a consequence of a mildly ...
Keerthana Harwalkar, Nobuko Yamanaka, Alain S. Pacis, Selina Zhao, Katie Teng, Warwick Pitman, Mitaali Taskar, Vera Lynn, Alex Frances Thornton, Matthew J. Ford, Yojiro Yamanaka   +10 more
wiley   +1 more source

The Role of Sperm Centrioles in Human Reproduction – The Known and the Unknown

Frontiers in Cell and Developmental Biology, 2019
Each human spermatozoon contains two remodeled centrioles that it contributes to the zygote. There, the centrioles reconstitute a centrosome that assembles the sperm aster and participate in pronuclei migration and cleavage. Thus, centriole abnormalities
Tomer Avidor-Reiss, Tomer Avidor-Reiss, Matthew Mazur, Matthew Mazur, Emily L. Fishman, Puneet Sindhwani, Puneet Sindhwani   +6 more
doaj   +1 more source

Avian Lifespan Network Reveals Shared Mechanisms and New Key Players in Animal Longevity

Aging Cell, EarlyView.
In this work, we found that birds with similar lifespans exhibit convergent evolution in specific genes, suggesting that shared evolutionary pressures shape the genetic basis of lifespan similarity across species. By investigating protein–protein interactions across genes evolving convergently in long‐ and short‐lived species, we identified a network ...
Mirko Martini, Giovanni Piccinini, Liliana Milani, Mariangela Iannello   +3 more
wiley   +1 more source

Molecular architecture of the C. elegans centriole.

PLoS Biology, 2022
Uncovering organizing principles of organelle assembly is a fundamental pursuit in the life sciences. Caenorhabditis elegans was key in identifying evolutionary conserved components governing assembly of the centriole organelle. However, localizing these
Alexander Woglar, Marie Pierron, Fabian Zacharias Schneider, Keshav Jha, Coralie Busso, Pierre Gönczy   +5 more
doaj   +1 more source

Intercellular Migration of Centrioles in the Germarium of \u3cem\u3eDrosophila melanogaster\u3c/em\u3e. An Electron Microscopic Study [PDF]

, 1970
A cluster of centrioles has been found in the early Drosophila oocyte. Since the oocyte is connected to 15 nurse cells by a system of intercellular bridges or ring canals, the possibility that the cluster of centrioles arose in the germarium from an ...
Mahowald, Anthony P., Strassheim, Joan M.   +1 more
core   +1 more source

Clockwise or anticlockwise? Turning the centriole triplets in the right direction! [PDF]

, 2007
International audienceCentrosomes are small cytoplasmic macromolecular assemblies composed from two major components, centrioles and pericentriolar material, each with its own complex architecture. This organelle is of interest because it plays a role in
Prigent, Claude, Uzbekov, Rustem
core   +3 more sources

The use of deidentified organ donor testes for research

Andrology, EarlyView.
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova, Marnie W. Skinner, Juliana I. Candelaria, Stephen R. Wellard, Philip W. Jordan   +4 more
wiley   +1 more source

Conserved molecular interactions in centriole-to-centrosome conversion. [PDF]

, 2015
Centrioles are required to assemble centrosomes for cell division and cilia for motility and signalling. New centrioles assemble perpendicularly to pre-existing ones in G1-S and elongate throughout S and G2.
A Grallert, A Rodrigues-Martins, Charlotte Mykura, CJ Tang, D Izquierdo, D Kitagawa, David M. Glover, EM Hatch, G Goshima, G Kohlmaier, G Lukinavicius, Giuliano Callaini, H Roque, H Varmark, Hélène Rangone, J Dobbelaere, J Fu, J Fu, J Gopalakrishnan, J Kleylein-Sohn, JE Sillibourne, Jennifer Chao-Chu, JH Sir, Jingyan Fu, K Kim, KF Sonnen, KF Sonnen, L Lau, M Bettencourt-Dias, M Bornens, M Hiraki, M Jerka-Dziadosz, M Martinez-Campos, M Ohta, M van Breugel, Marco Gottardo, Maria Giovanna Riparbelli, Mingwei Min, N Delgehyr, Nikola S. Dzhindzhev, NS Dzhindzhev, NS Dzhindzhev, O Cizmecioglu, R Habedanck, S Blachon, S Lawo, Sandra Schneider, SY Park, T Avidor-Reiss, TI Schmidt, TS Kim, V Mennella, V Mottier-Pavie, VJ Knorz, WJ Wang, YC Lin, Z Carvalho-Santos, Z Carvalho-Santos, Z Lipinszki, Z Lipinszki, ZA Novak, Zoltan Lipinszki   +61 more
core   +2 more sources

The absence of both RIBC1 and RIBC2 induces decreased sperm motility and litter size in male mice

Andrology, EarlyView.
Abstract Background RIBC1 (RIB43A domain with coiled‐coils 1) and RIBC2 (RIB43A domain with coiled‐coils 2) are homolog proteins of RIB43a which is localized to microtubules in the cilia and flagella of unicellular organisms. Cryo‐electron microscopy and artificial intelligence studies showed that RIBC1 and RIBC2 are microtubule inner proteins (MIPs ...
Kento Katsuma, Keisuke Shimada, Shingo Tonai, Daisuke Mashiko, Rie Iida‐Norita, Yuki Kaneda, Haruhiko Miyata, Masahito Ikawa   +7 more
wiley   +1 more source

Cell division: The renaissance of the centriole [PDF]

Current Biology, 1999
Centrioles are located at the center of the cytoskeleton and duplicate exactly once per cell cycle. Recent studies suggest that centrioles are required for the organization of a functional centrosome and that centriole assembly requires both gamma- and delta-tubulin.
Wallace F. Marshall, Joel L. Rosenbaum
openaire   +2 more sources