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WDR62 is required for proper proliferation and early differentiation of skeletal myoblasts. [PDF]

open access: yesCommun Biol
Ho UY   +10 more
europepmc   +1 more source

Flies without Centrioles [PDF]

open access: yesCell, 2006
Centrioles and centrosomes have an important role in animal cell organization, but it is uncertain to what extent they are essential for animal development. The Drosophila protein DSas-4 is related to the human microcephaly protein CenpJ and the C. elegans centriolar protein Sas-4.
Renata Basto   +2 more
exaly   +4 more sources
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The Centriole Mystique

Trends in Cell Biology, 2020
Centrioles organize the microtubule network and mitotic spindle and, as basal bodies, nucleate cilia and flagella. They undergo a beguiling process in which one appears to give rise to another and at a baffling orthogonal geometry. Nucleic acid-based replication has been pondered during cycles of zeniths and nadirs of plausibility, the latter now the ...
openaire   +2 more sources

No centriole, no centrosome

Trends in Cell Biology, 1999
The centriole is a cylinder of nine triplet microtubules found at the core of the centrosome. The location of centrioles within the centrosome has always seemed to suggest a role in centrosome function, but proof of this has remained elusive. In part, this is due to the lack of convenient methods to remove centrioles specifically.
openaire   +2 more sources

Positioning centrioles and centrosomes

open access: yesJournal of Cell Biology
Centrosomes are the primary microtubule organizer in eukaryotic cells. In addition to shaping the intracellular microtubule network and the mitotic spindle, centrosomes are responsible for positioning cilia and flagella. To fulfill these diverse functions, centrosomes must be properly located within cells, which requires that they undergo intracellular
Matthew R Hannaford   +2 more
exaly   +3 more sources

The centriole and the cell

Journal of Theoretical Biology, 1975
Abstract The endosymbiotic theory of the origin of the centriole is found lacking as no DNA has been found in the structure. The centriole is related to the ribosome in that it is a structure nucleated by RNA. This RNA (morphic) has the property of localizing itself at the site of the old centriole before nucleating a new one. The implication of this
openaire   +2 more sources

Centrioles in hepatocytes

Experientia, 1968
In der normalen und regenerierenden Rattenleber wurden Zentriolen gefunden. In der normalen Leberparenchymzelle erscheinen sie wahrscheinlich als Diplosomen. Haufig werden mehr als 2 Zentriolen in der einzelnen Leberparenchymzelle beobachtet, jedoch gibt es keine Anhaltspunkte fur eine zentriolare Replikation in den normalen Leberparenchymzellen ...
openaire   +2 more sources

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