Results 41 to 50 of about 15,297 (219)
Cellular Mechanisms of Ciliary Length Control
Cells, 2016 Cilia and flagella are evolutionarily conserved, membrane-bound, microtubule-based organelles on the surface of most eukaryotic cells. They play important roles in coordinating a variety of signaling pathways during growth, development, cell mobility ...
Jacob Keeling +2 more
doaj +1 more source
'Spindles' in symmetric spaces [PDF]
, 2005 We study families of submanifolds in symmetric spaces of compact type arising as exponential images of s-orbits of variable radii.
Quast, Peter
core +4 more sources
Truncation of POC1A associated with short stature and extreme insulin resistance [PDF]
, 2015 We describe a female proband with primordial dwarfism, skeletal dysplasia, facial dysmorphism, extreme dyslipidaemic insulin resistance and fatty liver associated with a novel homozygous frameshift mutation in POC1A, predicted to affect two of the three ...
Adams, Claire +29 more
core +3 more sources
Generation and Characterization of a Tissue-Specific Centrosome Indicator Mouse Line. [PDF]
, 2016 Centrosomes are major microtubule organizing centers (MTOCs) that play an important role in chromosome segregation during cell division. Centrosomes provide a stable anchor for microtubules, constituting the centers of the spindle poles in mitotic cells,
Chen, Ju +2 more
core +2 more sources
Current Opinion in Cell Biology, 2013 Centrioles are the key foundation of centrosomes and cilia, yet a molecular understanding of how they form has only recently begun to emerge. Building a fully functional centriole that can form a centrosome and cilium requires two cell cycles. Centriole building starts with procentriole nucleation, a process that is coordinated by the conserved ...
Tomer, Avidor-Reiss +1 more
openaire +2 more sources
Giant cell formation produced by laser microbeam irradiation of chromatin in Chinese hamster cells [PDF]
, 1981 A pulsed laser microbeam of wavelength 532 nm was used to produce visible small lesions in the nucleoplasm or in the cytoplasm of V79 Chinese hamster cells.
Altmann +34 more
core +2 more sources
cNap1 bridges centriole contact sites to maintain centrosome cohesion
PLoS Biology, 2022 Centrioles are non-membrane-bound organelles that participate in fundamental cellular processes through their ability to form physical contacts with other structures.
Robert Mahen
doaj +2 more sources
CEP19 cooperates with FOP and CEP350 to drive early steps in the ciliogenesis programme [PDF]
Open Biology, 2017 Primary cilia are microtubule-based sensory organelles necessary for efficient transduction of extracellular cues. To initiate cilia formation, ciliary vesicles (CVs) are transported to the vicinity of the centrosome where they dock to the distal end of ...
Bahareh A. Mojarad +6 more
doaj +1 more source
Current Biology, 2010 Centrioles are conserved microtubule-based organelles that lie at the core of the animal centrosome and play a crucial role in nucleating the formation of cilia and flagella in most eukaryotes. Centrioles have a complex ultrastructure with ninefold symmetry and a well-defined length.
Azimzadeh, Juliette +1 more
openaire +2 more sources
Mutations in DYNC2LI1 disrupt cilia function and cause short rib polydactyly syndrome. [PDF]
, 2015 The short rib polydactyly syndromes (SRPSs) are a heterogeneous group of autosomal recessive, perinatal lethal skeletal disorders characterized primarily by short, horizontal ribs, short limbs and polydactyly.
Daniel H. Cohn +12 more
core +2 more sources