Results 21 to 30 of about 7,876 (177)
Evolutionary conservation of centriole rotational asymmetry in the human centrosome
eLife, 2022 Centrioles are formed by microtubule triplets in a ninefold symmetric arrangement. In flagellated protists and animal multiciliated cells, accessory structures tethered to specific triplets render the centrioles rotationally asymmetric, a property that ...
Noémie Gaudin +11 more
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Prion, 2008 Early cell biologists perceived centrosomes to be permanent cellular structures. Centrosomes were observed to reproduce once each cycle and to orchestrate assembly a transient mitotic apparatus that segregated chromosomes and a centrosome to each daughter at the completion of cell division.
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Frontiers in Cell and Developmental Biology, 2019 The precursor of the flagellar axoneme is already present in the primary spermatocytes of Drosophila melanogaster. During spermatogenesis each primary spermatocyte shows a centriole pair that moves to the cell membrane and organizes an axoneme-based ...
Veronica Persico +2 more
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Interaction interface in the C-terminal parts of centriole proteins Sas6 and Ana2 [PDF]
Open Biology, 2020 The centriole is a ninefold symmetrical structure found at the core of centrosomes and, as a basal body, at the base of cilia, whose conserved duplication is regulated by Plk4 kinase.
Agnieszka Fatalska +3 more
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De novo centriole formation in human cells is error-prone and does not require SAS-6 self-assembly
eLife, 2015 Vertebrate centrioles normally propagate through duplication, but in the absence of preexisting centrioles, de novo synthesis can occur. Consistently, centriole formation is thought to strictly rely on self-assembly, involving self-oligomerization of the
Won-Jing Wang +5 more
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Cells, 2020 Centrioles are microtubule-based cellular structures present in most human cells that build centrosomes and cilia. Proliferating cells have only two centrosomes and this number is stringently maintained through the temporally and spatially controlled ...
Catherine Sullenberger +3 more
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Stable centrosomal roots disentangle to allow interphase centriole independence.
PLoS Biology, 2018 The centrosome is a non-membrane-bound cellular compartment consisting of 2 centrioles surrounded by a protein coat termed the pericentriolar material (PCM).
Robert Mahen
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Centrioles are amplified in cycling progenitors of olfactory sensory neurons.
PLoS Biology, 2020 Olfaction in most animals is mediated by neurons bearing cilia that are accessible to the environment. Olfactory sensory neurons (OSNs) in chordates usually have multiple cilia, each with a centriole at its base. OSNs differentiate from stem cells in the
Kaitlin Ching, Tim Stearns
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Current Opinion in Cell Biology, 2009 Centrioles are cylindrical structures found at the core of the mitotic spindle pole, which also act as basal bodies to nucleate the formation of cilia. Centrioles have a complex, ninefold symmetric structure, and reproduce by an intriguing duplication process. The complexity and apparent self-reproduction of centrioles raises the question of how such a
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Overview of the centriole architecture
Current Opinion in Structural Biology, 2021 The centriole is a magnificent molecular assembly of several giga-daltons, one of the largest of the eukaryotic cell, and whose atomic structure remains unsolved to date. However, numerous electron microscopy, cryo-tomography, and super-resolution studies now make it possible to establish a global architectural view of it with its different sub-regions.
LeGuennec, Maeva +4 more
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