Results 1 to 10 of about 7,807 (115)
Atypical centrioles are present in Tribolium sperm [PDF]
Open Biology, 2017 Typical centrioles are made of microtubules organized in ninefold symmetry. Most animal somatic cells have two centrioles for normal cell division and function.
Tomer Avidor-Reiss
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C. elegans SSNA-1 is required for the structural integrity of centrioles and bipolar spindle assembly [PDF]
Nature CommunicationsCentrioles play key roles in mitotic spindle assembly. Once assembled, centrioles exhibit long-term stability, but how stability is achieved and how it is regulated are not completely understood.
Jason A. Pfister +10 more
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Pix Proteins and the Evolution of Centrioles
PLoS ONE, 2008 We have made a wide phylogenetic survey of Pix proteins, which are constituents of vertebrate centrioles in most eukaryotes. We have also surveyed the presence and structure of flagella or cilia and centrioles in these organisms, as far as is possible ...
Hugh R Woodland, Andrew M Fry
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Meiotic divisions and round spermatid formation do not require centriole duplication in mice. [PDF]
PLoS GeneticsCentrosomes, composed of centrioles and pericentriolar matrix proteins, are traditionally viewed as essential microtubule-organizing centers (MTOCs) that facilitate bipolar spindle formation and chromosome segregation during spermatogenesis.
Marnie W Skinner +3 more
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Long-range migration of centrioles to the apical surface of the olfactory epithelium
eLife, 2022 Olfactory sensory neurons (OSNs) in vertebrates detect odorants using multiple cilia, which protrude from the end of the dendrite and require centrioles for their formation. In mouse olfactory epithelium, the centrioles originate in progenitor cells near
Kaitlin Ching +2 more
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Estrogens—Origin of Centrosome Defects in Human Cancer?
Cells, 2022 Estrogens are associated with a variety of diseases and play important roles in tumor development and progression. Centrosome defects are hallmarks of human cancers and contribute to ongoing chromosome missegragation and aneuploidy that manifest in ...
Miriam Bühler, Ailine Stolz
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Mechanical stretch scales centriole number to apical area via Piezo1 in multiciliated cells
eLife, 2021 How cells count and regulate organelle number is a fundamental question in cell biology. For example, most cells restrict centrioles to two in number and assemble one cilium; however, multiciliated cells (MCCs) synthesize hundreds of centrioles to ...
Saurabh Kulkarni +5 more
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Cells, 2020 Drosophila spermatocytes have giant centrioles that display unique properties. Both the parent centrioles maintain a distinct cartwheel and nucleate a cilium-like region that persists during the meiotic divisions and organizes a structured sperm axoneme.
Veronica Persico +3 more
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Experimental and Natural Induction of de novo Centriole Formation
Frontiers in Cell and Developmental Biology, 2022 In cycling cells, new centrioles are assembled in the vicinity of pre-existing centrioles. Although this canonical centriole duplication is a tightly regulated process in animal cells, centrioles can also form in the absence of pre-existing centrioles ...
Kasuga Takumi, Daiju Kitagawa
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Centrosome Formation in the Bovine Early Embryo
Cells, 2023 Centrosome formation during early development in mice and rats occurs due to the appearance of centrioles de novo. In contrast, in humans and other non-rodent mammals, centrioles are thought to be derived from spermatozoa.
Rustem Uzbekov +5 more
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