Results 1 to 10 of about 15,297 (219)

A missense mutation in the PISA domain of HsSAS-6 causes autosomal recessive primary microcephaly in a large consanguineous Pakistani family [PDF]

, 2017
Asymmetric cell division is essential for normal human brain development. Mutations in several genes encoding centrosomal proteins that participate in accurate cell division have been reported to cause autosomal recessive primary microcephaly (MCPH).
Altmüller, Janine, Ansar, Muhammad, Baig, Shahid M., Enzinger, Christian, Gönczy, Pierre, Hussain, Muhammad S., Höhne, Wolfgang, Khan, Muzammil A., Nürnberg, Gudrun, Nürnberg, Peter, Orpinell, Meritxell, Rupp, Verena M., Speicher, Michael R., Steinmetz, Michel O., Thiele, Holger, Vincent, John B., Windpassinger, Christian   +16 more
core  

Realizing the physics of motile cilia synchronization with driven colloids

, 2015
Cilia and flagella in biological systems often show large scale cooperative behaviors such as the synchronization of their beats in "metachronal waves".
Bruot, Nicolas, Cicuta, Pietro
core   +1 more source

The kinase ZYG-1 phosphorylates the cartwheel protein SAS-5 to drive centriole assembly in C. elegans

EMBO Reports
Centrioles organize centrosomes, the cell’s primary microtubule-organizing centers (MTOCs). Centrioles double in number each cell cycle, and mis-regulation of this process is linked to diseases such as cancer and microcephaly. In C.
Prabhu Sankaralingam, Shaohe Wang, Yan Liu, Karen F Oegema, Kevin F O’Connell   +4 more
doaj   +1 more source

A founder CEP120 mutation in Jeune asphyxiating thoracic dystrophy expands the role of centriolar proteins in skeletal ciliopathies [PDF]

, 2017
Jeune asphyxiating thoracic dystrophy (JATD) is a skeletal dysplasia characterized by a small thoracic cage and a range of skeletal and extra-skeletal anomalies.
Alamro, Rana, Alkuraya, Fowzan S., Almoisheer, Agaadir, Alshiddi, Tarfa, Alzahrani, Fatma, Beales, Philip L., Faqeih, Eissa, Hashem, Amal, Holder, Isabel, Lausch, Ekkehart, Mitchison, Hannah M., Schmidts, Miriam, Shaheen, Ranad, Superti-Furga, Andrea   +13 more
core  

The Centrosomes of Haploid and Diploid Cells Have an Equal Number of Centrioles in the Parasitoid Wasp Anisopteromalus Calandrae

Frontiers in Bioscience-Landmark
Background: The centrosome is the main center of the organization of microtubules (MT) in the cell, the origin for the formation of flagella and cilia, as well as the site of many regulatory intracellular processes.
Rustem Uzbekov, San-Whouly Mauricette Ouali N'goran, Anastasiia Garanina, Massimo Pancione, Stanislav Yu. Chaika, Christophe Bressac   +5 more
doaj   +1 more source

Centrioles, centrosomes, and cilia in health and disease [PDF]

, 2010
Centrioli su valjkaste strukture okružene pericentriolarnom tvari koje izgrađuju centrosome, a centriol naslijeđen od majke ima ključnu ulogu u formiranju trepetljika.
Vidan, Nikolina
core   +2 more sources

The evolution of centriole degradation in mouse sperm

Nature Communications
Centrioles are subcellular organelles found at the cilia base with an evolutionarily conserved structure and a shock absorber-like function. In sperm, centrioles are found at the flagellum base and are essential for embryo development in basal animals ...
Sushil Khanal, Ankit Jaiswal, Rajanikanth Chowdanayaka, Nahshon Puente, Katerina Turner, Kebron Yeshitela Assefa, Mohamad Nawras, Ezekiel David Back, Abigail Royfman, James P. Burkett, Soon Hon Cheong, Heidi S. Fisher, Puneet Sindhwani, John Gray, Nallur Basappa Ramachandra, Tomer Avidor-Reiss   +15 more
doaj   +1 more source

9-fold symmetry is not essential for centriole elongation and formation of new centriole-like structures

Nature Communications
As daughter centrioles assemble during G2, they recruit conserved Ana3/RTTN followed by its partner Rcd4/PPP1R35. Together, this contributes to the subsequent recruitment of Ana1/CEP295, required for the centriole’s conversion to a centrosome.
Pallavi Panda, Mark S. Ladinsky, David M. Glover   +2 more
doaj   +1 more source

Insights into the zebrafish left-right organizer's centrosomes and cilia via volume electron microscopy. [PDF]

Biol Open
Ononiwu F, Adhya AL, Mikolaj M, Dell C, Shamil AW, Narayan K, Hehnly H.   +6 more
europepmc   +1 more source

A centrally positioned cluster of multiple centrioles in antigen-presenting cells fosters T cell activation. [PDF]

Nat Commun
Stötzel I, Weier AK, Sarkar A, Som S, Bach L, Konopka P, Miková E, Ghosh S, Böthling J, Homrich M, Schaedel L, Kazmaier U, Symeonidis K, Ebner S, Weidner P, Abdullah Z, Meissner F, Uderhardt S, Hons M, Baumjohann D, Paul R, Rieger H, Kiermaier E.   +22 more
europepmc   +1 more source