Results 61 to 70 of about 7,876 (177)

Identification of Distinct Interacting Proteins of Giardia lamblia Centrins Using Yeast Two‐Hybrid Assays

open access: yesJournal of Eukaryotic Microbiology, Volume 73, Issue 4, July/August 2026.
ABSTRACT Giardia lamblia, a protozoan parasite that causes diarrhea in humans, contains two centrins implicated in cellular morphology and cell division. To identify proteins interacting with each G. lamblia centrin (GlCent), we performed a yeast two‐hybrid assay.
Mee Young Shin   +2 more
wiley   +1 more source

Cep120 is asymmetrically localized to the daughter centriole and is essential for centriole assembly [PDF]

open access: yesJournal of Cell Biology, 2010
Centrioles form the core of the centrosome in animal cells and function as basal bodies that nucleate and anchor cilia at the plasma membrane. In this paper, we report that Cep120 (Ccdc100), a protein previously shown to be involved in maintaining the neural progenitor pool in mouse brain, is associated with centriole structure and function.
Mahjoub, Moe R.   +2 more
openaire   +2 more sources

Wave Mechanics of Ciliary Proteins: Quantum‐Enabled Sensing and Energy Transfer in the “Cellular Antenna”

open access: yesAggregate, Volume 7, Issue 6, June 2026.
This review surveys eukaryotic cilia as putative quantum‐enabled sensory and regulatory centers. It highlights their multifaceted roles in the cell, focuses on the nontrivial roles of quantum mechanics in their membrane and cytoskeletal proteins, and introduces the essential building blocks enabling quantum properties to survive in the warm, wet, and ...
Daniel L. Bilezikian   +5 more
wiley   +1 more source

The crucial role of centrioles in tooth growth and development

open access: yesJournal of the Formosan Medical Association
Background: Tooth development hinged on reciprocal interactions between enamel and dentin, shaping tooth structures. Centrioles influenced cellular direction, critical for stem cell differentiation.
Shan-Li Pei   +2 more
doaj   +1 more source

Unveiling a New Link: Cholesterol Deficiency in Smith–Lemli–Opitz and Niemann–Pick C as a Driver of Ciliopathies

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1179-1191, June 2026.
ABSTRACT The ciliopathies are a group of genetic disorders caused by defective function of either the primary cilia (a large number) or the motile cilia (a much smaller number). These have been defined as diseases with mutations in genes encoding individual ciliary or cilia‐associated proteins.
Robert P. Erickson   +1 more
wiley   +1 more source

Cilia in Nervous System Development, Function, and Disease

open access: yesMedComm – Future Medicine, Volume 5, Issue 2, June 2026.
Cilia are evolutionarily conserved organelles that function as essential sensory and motility platforms in the nervous system. This review outlines key cilia‐dependent signaling pathways and their roles in neural development and function. Furthermore, it highlights how ciliary dysfunction can lead to a variety of neurological disorders, known as ...
Qingchao Li, Anqi Zhang, Ting Song
wiley   +1 more source

Ana1/CEP295 is an essential player in the centrosome maintenance program regulated by Polo kinase and the PCM

open access: yesEMBO Reports
Centrioles are part of centrosomes and cilia, which are microtubule organising centres (MTOC) with diverse functions. Despite their stability, centrioles can disappear during differentiation, such as in oocytes, but little is known about the regulation ...
Ana Pimenta-Marques   +6 more
doaj   +1 more source

Roles of centrioles in neural attraction of dental pulp stem cells

open access: yesJournal of the Formosan Medical Association
Background/Purpose: Human nerve development is vital, affecting trauma recovery and dental issues. Early embryonic clues link nerves to tooth development via factors like Wnt and Hedgehog pathways.
Shan-Li Pei   +2 more
doaj   +1 more source

Monoclonal Antibodies Accessing the Cytosol of Living Cells and Binding to Polo‐Like Kinase 1 Interdomain Linker Affect Mitotic Behavior

open access: yesChemBioChem, Volume 27, Issue 9, 14 May 2026.
Monoclonal antibodies targeting the interdomain region of polo‐like kinase 1 (PLK1) were delivered into living HeLa cells by electroporation to directly modulate mitotic progression. This intracellular antibody approach provides a new tool to probe PLK1 function and highlights the potential of antibodies to regulate key mitotic regulators inside cells.
Clément Steyer   +5 more
wiley   +1 more source

Centriole triplet microtubules are required for stable centriole formation and inheritance in human cells

open access: yeseLife, 2017
Centrioles are composed of long-lived microtubules arranged in nine triplets. However, the contribution of triplet microtubules to mammalian centriole formation and stability is unknown.
Jennifer T Wang   +4 more
doaj   +1 more source

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