Results 71 to 80 of about 15,297 (219)
The importance of a single primary cilium [PDF]
The centrosome is the main microtubule-organizing center in animal cells, and helps to influence the morphology of the microtubule cytoskeleton in interphase and mitosis. The centrosome also templates the assembly of the primary cilium, and together they
Mahjoub, Moe R
core +2 more sources
Coping with centriole loss: pericentriolar material maintenance after centriole degeneration
Shortly after the onset of ciliogenesis in Caenorhabditis elegans sensory neurons, the centrioles/basal bodies undergo degeneration. The fate of the pericentriolar material (PCM) that was associated with those centrioles has, however, remained unknown ...
Carla M. C. Abreu, Tiago J. Dantas
doaj +1 more source
Centriole assembly and the role of Mps1: defensible or dispensable? [PDF]
The Mps1 protein kinase is an intriguing and controversial player in centriole assembly. Originally shown to control duplication of the budding yeast spindle pole body, Mps1 is present in eukaryotes from yeast to humans, the nematode C.
Amanda N Pike, Harold A Fisk
core +1 more source
Identification of novel genes regulating the development of the palate
Abstract Background The International Mouse Phenotyping Consortium (IMPC) has generated thousands of knockout mouse lines, many of which exhibit embryonic or perinatal lethality. Using micro‐computed tomography (micro‐CT), the IMPC has created and publicly released three‐dimensional image data sets of embryos from these lethal and subviable lines.
Ashwin Bhaskar, Sophie Astrof
wiley +1 more source
Atypical centrioles are present in Tribolium sperm [PDF]
Typical centrioles are made of microtubules organized in ninefold symmetry. Most animal somatic cells have two centrioles for normal cell division and function.
E. L. Fishman +6 more
doaj +1 more source
The mechanism regulating the dissociation of the centrosomal protein C-Nap1 from mitotic spindle poles [PDF]
The centrosomal protein C-Nap1 is thought to play an important role in centrosome cohesion during interphase of the cell cycle. At the onset of mitosis, when centrosomes separate for bipolar spindle formation, C-Nap1 dissociates from centrosomes. Here we
Hacker, Ulrike +3 more
core
SnapShot: Centriole Biogenesis
SPD2 (Ce, Dm)/CEP192 (Hs)No centriole duplication (Ce);
Bettencourt-Dias, Mónica +1 more
openaire +3 more sources
The use of deidentified organ donor testes for research
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova +4 more
wiley +1 more source
Proper ciliary basal body positioning within a cell is key for cilia functioning. Centriole and basal body positioning depends on signaling pathways such as the planar cell polarity pathway (PCP) governed by Frizzled (Fz-PCP).
Sergio Garrido-Jimenez +2 more
doaj +1 more source
On the use of clustering and the MeSH controlled vocabulary to improve MEDLINE abstract search [PDF]
Databases of genomic documents contain substantial amounts of structured information in addition to the texts of titles and abstracts. Unstructured information retrieval techniques fail to take advantage of the structured information available.
Blott, Stephen +3 more
core

