Results 71 to 80 of about 15,297 (219)

The importance of a single primary cilium [PDF]

open access: yes, 2013
The centrosome is the main microtubule-organizing center in animal cells, and helps to influence the morphology of the microtubule cytoskeleton in interphase and mitosis. The centrosome also templates the assembly of the primary cilium, and together they
Mahjoub, Moe R
core   +2 more sources

Coping with centriole loss: pericentriolar material maintenance after centriole degeneration

open access: yesCommunications Biology, 2021
Shortly after the onset of ciliogenesis in Caenorhabditis elegans sensory neurons, the centrioles/basal bodies undergo degeneration. The fate of the pericentriolar material (PCM) that was associated with those centrioles has, however, remained unknown ...
Carla M. C. Abreu, Tiago J. Dantas
doaj   +1 more source

Centriole assembly and the role of Mps1: defensible or dispensable? [PDF]

open access: yes, 2011
The Mps1 protein kinase is an intriguing and controversial player in centriole assembly. Originally shown to control duplication of the budding yeast spindle pole body, Mps1 is present in eukaryotes from yeast to humans, the nematode C.
Amanda N Pike, Harold A Fisk
core   +1 more source

Identification of novel genes regulating the development of the palate

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The International Mouse Phenotyping Consortium (IMPC) has generated thousands of knockout mouse lines, many of which exhibit embryonic or perinatal lethality. Using micro‐computed tomography (micro‐CT), the IMPC has created and publicly released three‐dimensional image data sets of embryos from these lethal and subviable lines.
Ashwin Bhaskar, Sophie Astrof
wiley   +1 more source

Atypical centrioles are present in Tribolium sperm [PDF]

open access: yesOpen Biology, 2017
Typical centrioles are made of microtubules organized in ninefold symmetry. Most animal somatic cells have two centrioles for normal cell division and function.
E. L. Fishman   +6 more
doaj   +1 more source

The mechanism regulating the dissociation of the centrosomal protein C-Nap1 from mitotic spindle poles [PDF]

open access: yes, 2002
The centrosomal protein C-Nap1 is thought to play an important role in centrosome cohesion during interphase of the cell cycle. At the onset of mitosis, when centrosomes separate for bipolar spindle formation, C-Nap1 dissociates from centrosomes. Here we
Hacker, Ulrike   +3 more
core  

SnapShot: Centriole Biogenesis

open access: yesCell, 2009
SPD2 (Ce, Dm)/CEP192 (Hs)No centriole duplication (Ce);
Bettencourt-Dias, Mónica   +1 more
openaire   +3 more sources

The use of deidentified organ donor testes for research

open access: yesAndrology, EarlyView.
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova   +4 more
wiley   +1 more source

Diminished Expression of Fat and Dachsous PCP Proteins Impaired Centriole Planar Polarization in Drosophila

open access: yesFrontiers in Genetics, 2019
Proper ciliary basal body positioning within a cell is key for cilia functioning. Centriole and basal body positioning depends on signaling pathways such as the planar cell polarity pathway (PCP) governed by Frizzled (Fz-PCP).
Sergio Garrido-Jimenez   +2 more
doaj   +1 more source

On the use of clustering and the MeSH controlled vocabulary to improve MEDLINE abstract search [PDF]

open access: yes, 2005
Databases of genomic documents contain substantial amounts of structured information in addition to the texts of titles and abstracts. Unstructured information retrieval techniques fail to take advantage of the structured information available.
Blott, Stephen   +3 more
core  

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