Results 71 to 80 of about 7,876 (177)

Cep295 is a conserved scaffold protein required for generation of a bona fide mother centriole

Nature Communications, 2016
Newly formed centrioles mature into functional mother centrioles. Here the authors show that the scaffolding protein Cep295 is recruited to the procentriole assembly site and assists daughter centriole assembly and daughter-to-mother centriole conversion.
Yuki Tsuchiya, Satoko Yoshiba, Akshari Gupta, Koki Watanabe, Daiju Kitagawa   +4 more
doaj   +1 more source

Centrioles: Duplicating Precariously [PDF]

Current Biology, 2007
To assemble a mitotic spindle and accurately segregate chromosomes to progeny, a cell needs to precisely regulate its centrosome number, a feat largely accomplished through the tight control of centriole duplication. Recent work showing that the overexpression of centriolar proteins can lead to the formation of multiple centrioles in the absence of pre-
openaire   +2 more sources

Ultrastructure of the Spermiogenesis in Halyomorpha halys (Hemiptera: Pentatomidae): X-Irradiation and New Insights on the Centriolar Region Organization

Insects
Halyomorpha halys (Heteroptera: Pentatomidae) is an insect pest native to Asia that has spread over the last two decades to most of the North America, parts of South America, Europe and North Africa.
Francesco Paoli, Massimo Cristofaro, Gerardo Roselli, Raffaele Sasso, Sergio Musmeci, Francesco Barbieri, Chiara Sciandra, Valentina Vanoni, Loris Menegotti, Pio Federico Roversi, Gianfranco Anfora, David Mercati, Romano Dallai   +12 more
doaj   +1 more source

Dynamics of centriole amplification in centrosome-depleted brain multiciliated progenitors

Scientific Reports, 2019
Reproductive and respiratory organs, along with brain ventricles, are lined by multiciliated epithelial cells (MCC) that generate cilia-powered fluid flows.
Olivier Mercey, Adel Al Jord, Philippe Rostaing, Alexia Mahuzier, Aurélien Fortoul, Amélie-Rose Boudjema, Marion Faucourt, Nathalie Spassky, Alice Meunier   +8 more
doaj   +1 more source

CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion

Nature Communications, 2020
During cell division, centrosomes duplicate and newly formed centrioles must undergo centriole-to-centrosome conversion, but the molecular details are unclear.
Enrico S. Atorino, Shoji Hata, Charlotta Funaya, Annett Neuner, Elmar Schiebel   +4 more
doaj   +1 more source

Regulation of cilia abundance in multiciliated cells

eLife, 2019
Multiciliated cells (MCC) contain hundreds of motile cilia used to propel fluid over their surface. To template these cilia, each MCC produces between 100-600 centrioles by a process termed centriole amplification.
Rashmi Nanjundappa, Dong Kong, Kyuhwan Shim, Tim Stearns, Steven L Brody, Jadranka Loncarek, Moe R Mahjoub   +6 more
doaj   +1 more source

Rapid Evolution of Sperm Produces Diverse Centriole Structures that Reveal the Most Rudimentary Structure Needed for Function

Cells, 2018
Centrioles are ancient subcellular protein-based organelles that maintain a conserved number and structure across many groups of eukaryotes. Centriole number (two per cells) is tightly regulated; each pre-existing centriole nucleates only one centriole ...
Tomer Avidor-Reiss
doaj   +1 more source

A delta-tubulin/epsilon-tubulin/Ted protein complex is required for centriole architecture

eLife
Centrioles have a unique, conserved architecture formed by three linked, ‘triplet’, microtubules arranged in ninefold symmetry. The mechanisms by which these triplet microtubules are formed remain unclear but likely involve the noncanonical tubulins ...
Rachel Pudlowski, Lingyi Xu, Ljiljana Milenkovic, Chandan Kumar, Katherine Hemsworth, Zayd Aqrabawi, Tim Stearns, Jennifer T Wang   +7 more
doaj   +1 more source

Mechanisms of axoneme and centriole elimination in Naegleria gruberi

EMBO Reports
The early branching eukaryote Naegleria gruberi can transform transiently from an amoeboid life form lacking centrioles and flagella to a flagellate life form where these elements are present, followed by reversion to the amoeboid state.
Alexander Woglar, Coralie Busso, Gabriela Garcia-Rodriguez, Friso Douma, Marie Croisier, Graham Knott, Pierre Gönczy   +6 more
doaj   +1 more source

The kinase ZYG-1 phosphorylates the cartwheel protein SAS-5 to drive centriole assembly in C. elegans

EMBO Reports
Centrioles organize centrosomes, the cell’s primary microtubule-organizing centers (MTOCs). Centrioles double in number each cell cycle, and mis-regulation of this process is linked to diseases such as cancer and microcephaly. In C.
Prabhu Sankaralingam, Shaohe Wang, Yan Liu, Karen F Oegema, Kevin F O’Connell   +4 more
doaj   +1 more source