Results 71 to 80 of about 7,733 (159)

Ana1/CEP295 is an essential player in the centrosome maintenance program regulated by Polo kinase and the PCM

EMBO Reports
Centrioles are part of centrosomes and cilia, which are microtubule organising centres (MTOC) with diverse functions. Despite their stability, centrioles can disappear during differentiation, such as in oocytes, but little is known about the regulation ...
Ana Pimenta-Marques, Tania Perestrelo, Patricia Reis-Rodrigues, Paulo Duarte, Ana Ferreira-Silva, Mariana Lince-Faria, Mónica Bettencourt-Dias   +6 more
doaj   +1 more source

Centriole triplet microtubules are required for stable centriole formation and inheritance in human cells

eLife, 2017
Centrioles are composed of long-lived microtubules arranged in nine triplets. However, the contribution of triplet microtubules to mammalian centriole formation and stability is unknown.
Jennifer T Wang, Dong Kong, Christian R Hoerner, Jadranka Loncarek, Tim Stearns   +4 more
doaj   +1 more source

Roles of centrioles in neural attraction of dental pulp stem cells

Journal of the Formosan Medical Association
Background/Purpose: Human nerve development is vital, affecting trauma recovery and dental issues. Early embryonic clues link nerves to tooth development via factors like Wnt and Hedgehog pathways.
Shan-Li Pei, Rung-Shu Chen, Min-Huey Chen   +2 more
doaj   +1 more source

Cep295 is a conserved scaffold protein required for generation of a bona fide mother centriole

Nature Communications, 2016
Newly formed centrioles mature into functional mother centrioles. Here the authors show that the scaffolding protein Cep295 is recruited to the procentriole assembly site and assists daughter centriole assembly and daughter-to-mother centriole conversion.
Yuki Tsuchiya, Satoko Yoshiba, Akshari Gupta, Koki Watanabe, Daiju Kitagawa   +4 more
doaj   +1 more source

Male gametogenesis without centrioles

Developmental Biology, 2011
The orientation of the mitotic spindle plays a central role in specifying stem cell-renewal by enabling interaction of the daughter cells with external cues: the daughter cell closest to the hub region is instructed to self-renew, whereas the distal one starts to differentiate.
Riparbelli, Maria Giovanna, Callaini, Giuliano   +1 more
openaire   +3 more sources

Ultrastructure of the Spermiogenesis in Halyomorpha halys (Hemiptera: Pentatomidae): X-Irradiation and New Insights on the Centriolar Region Organization

Insects
Halyomorpha halys (Heteroptera: Pentatomidae) is an insect pest native to Asia that has spread over the last two decades to most of the North America, parts of South America, Europe and North Africa.
Francesco Paoli, Massimo Cristofaro, Gerardo Roselli, Raffaele Sasso, Sergio Musmeci, Francesco Barbieri, Chiara Sciandra, Valentina Vanoni, Loris Menegotti, Pio Federico Roversi, Gianfranco Anfora, David Mercati, Romano Dallai   +12 more
doaj   +1 more source

CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion

Nature Communications, 2020
During cell division, centrosomes duplicate and newly formed centrioles must undergo centriole-to-centrosome conversion, but the molecular details are unclear.
Enrico S. Atorino, Shoji Hata, Charlotta Funaya, Annett Neuner, Elmar Schiebel   +4 more
doaj   +1 more source

Rapid Evolution of Sperm Produces Diverse Centriole Structures that Reveal the Most Rudimentary Structure Needed for Function

Cells, 2018
Centrioles are ancient subcellular protein-based organelles that maintain a conserved number and structure across many groups of eukaryotes. Centriole number (two per cells) is tightly regulated; each pre-existing centriole nucleates only one centriole ...
Tomer Avidor-Reiss
doaj   +1 more source

Regulation of cilia abundance in multiciliated cells

eLife, 2019
Multiciliated cells (MCC) contain hundreds of motile cilia used to propel fluid over their surface. To template these cilia, each MCC produces between 100-600 centrioles by a process termed centriole amplification.
Rashmi Nanjundappa, Dong Kong, Kyuhwan Shim, Tim Stearns, Steven L Brody, Jadranka Loncarek, Moe R Mahjoub   +6 more
doaj   +1 more source

Centrioles take center stage [PDF]

Current Biology, 2001
Centrioles are among the most beautiful and mysterious of all cell organelles. Although the ultrastructure of centrioles has been studied in great detail ever since the advent of electron microscopy, these studies raised as many questions as they answered, and for a long time both the function and mode of duplication of centrioles remained ...
openaire   +2 more sources