Results 111 to 120 of about 74,831 (235)
Aurora-A Breaks Symmetry in Contractile Actomyosin Networks Independently of Its Role in Centrosome Maturation [PDF]
Peng Zhao +6 more
openalex +1 more source
Molecular landscape and functional characterization of centrosome amplification in ovarian cancer [PDF]
Carolin M. Sauer +21 more
openalex +1 more source
Ubiquitination dynamics in human tumour viruses: Viral infection, oncogenesis and antiviral therapy
The ubiquitin system is essential for cellular homeostasis and regulates many processes. Viruses, including oncogenic ones, exploit or evade this system to survive and replicate. This review explores how human tumour viruses manipulate the ubiquitination system to complete their life cycle, evade immunity and promote cancer.
Oscar Trejo‐Cerro +2 more
wiley +1 more source
Calcineurin associates with centrosomes and regulates cilia length maintenance [PDF]
Eirini Tsekitsidou +6 more
openalex +1 more source
Synthetic trap‐peptides identify a TOM complex phosphatase – PP2A dephosphorylates Tom6
Synthetic trap‐peptides facilitate the identification of complete holoenzymes that bind to the target sequence remarkably close to the phosphorylation site. PP4 bound to, but did not dephosphorylate, the peptide substrate taken from yeast Tom6 pSer16, showing that proximity alone does not induce phosphatase activity.
Laura Scheinost +7 more
wiley +1 more source
Mechanosensing in Dendritic Cells
ABSTRACT Since their discovery, dendritic cells have been recognized for their unusual capacity to sense and respond to physical stimuli within their environment. However, it took nearly two decades—and the advent of mechanobiology—to elucidate the underlying mechanisms and functional implications of this mechanical hypersensitivity. In this review, we
Vincent Calmettes +5 more
wiley +1 more source
A fluorescence lifetime separation approach for FLIM live‐cell imaging
Abstract Fluorescence lifetime imaging microscopy (FLIM) translates the duration of excited states of fluorophores into lifetime information as an additional source of contrast in images of biological samples. This offers the possibility to separate fluorophores particularly beneficial in case of similar excitation spectra.
Cornelia Wetzker +8 more
wiley +1 more source
Piezo1 in intestinal smooth muscle cells: Emerging perspectives
Abstract figure legend Loss of Piezo1 in SMCs results in delayed gut transit, impaired small bowel contractility, and tissue alterations. But more critically, Piezo1 is shown to be intracellularly localized, highlighting important implications given the phenotype. Adapted from Bautista, G.M. et al.
Geoanna M. Bautista +2 more
wiley +1 more source

