Results 61 to 70 of about 28,742 (199)
Coacervate‐Droplet Cased Synthetic Cells Regulated By Activated Carboxylic Acids (ACAs)
ChemSystemsChem, EarlyView.The activated carboxylic acid (ACA) reaction cycle, usually employed to transiently change the solution pH, has been exploited to precisely control the lifetime of peptide‐based coacervates. This study underscores the potential of ACA‐fueled coacervates as a platform for investigating biomolecular condensates and developing synthetic life systems ...
Matteo Valentini +2 more
wiley +1 more source
Cytoplasmic flows as signatures for the mechanics of mitotic positioning [PDF]
arXiv, 2015 The proper positioning of the mitotic spindle is crucial for asymmetric cell division and generating cell diversity during development. Proper position in the single-cell embryo of Caenorhabditis elegans is achieved initially by the migration and rotation of the pronuclear complex (PNC) and its two associated centrosomal arrays of microtubules (MTs ...
arxiv
CP91 is a component of the Dictyostelium centrosome involved in centrosome biogenesis
European Journal of Cell Biology, 2016 The Dictyostelium centrosome is a model for acentriolar centrosomes and it consists of a three-layered core structure surrounded by a corona harboring microtubule nucleation complexes. Its core structure duplicates once per cell cycle at the G2/M transition.
Putzler, Sascha +2 more
openaire +3 more sources
The use of deidentified organ donor testes for research
Andrology, EarlyView.Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova +4 more
wiley +1 more source
Clinical Genetics, EarlyView.Two deleterious protein‐truncating NLRP2 variants were identified in a patient with female infertility, four early miscarriages, and one failed attempt of intracytoplasmic sperm injection. The variants mediate mRNA decay and alter NLRP2 structure and interactions with other members of the SCMC.
Zeynep Yalcin +8 more
wiley +1 more source
HN1 Functions in Protein Synthesis Regulation via mTOR‐RPS6 Axis and Maintains Nucleolar Integrity
Cell Proliferation, EarlyView.HN1 is required for nucleolar homeostasis which is the site of ribosome biogenesis and protein synthesis when its mRNA is knocked down by shRNA, it depletes in cytoplasm and the protein synthesis is downregulated in comparison to controls. Thus, the proliferating cells requiring vast number of nucleosomes, are arrested at S onset.
Gülseren Özduman +4 more
wiley +1 more source
Membraneless Organelles and Phase Separation in Tumours: Mechanisms and Prospects
Cell Proliferation, EarlyView.The Salient and Novel Findings: This article summarises the latest research advancements in phase separation within tumours, with a particular focus on the role and molecular mechanisms of liquid–liquid phase separation (LLPS) in tumour progression.
Hao Yang +3 more
wiley +1 more source
Imaging malaria parasites across scales and time
Journal of Microscopy, EarlyView.Abstract The idea that disease is caused at the cellular level is so fundamental to us that we might forget the critical role microscopy played in generating and developing this insight. Visually identifying diseased or infected cells lays the foundation for any effort to curb human pathology.
Julien Guizetti
wiley +1 more source
Navigating the nexus: a perspective of centrosome -cytoskeleton interactions [PDF]
arXivA structural relationship between the centrosome and cytoskeleton has been recognized for many years. Centrosomes typically reside near the nucleus, establishing and maintaining the nucleus-centrosome axis. This spatial arrangement is critical for determining cell polarity during interphase and ensuring the proper assembly of the spindle apparatus ...
arxiv