Results 71 to 80 of about 418 (139)

Antibacterial and antibiofilm activities of ceragenins againstAchromobacterspecies isolated from cystic fibrosis patients

, 2020
Achromobacter species, which are recognized as emerging pathogens isolated from patients with cystic fibrosis, are capable of forming biofilm in the respiratory tract in patients and innate multidrug resistance to antimicrobials.
Mataraci-Kara, Emel, Damar-Celik, Damla, Savage, Paul B., Ozbek-Celik, Berna, Damla Damar-Çelik, Emel Mataracı-Kara, Paul B. Savage, Berna Özbek-Çelik   +7 more
core   +1 more source

Stenotrophomonas maltophilia infections – Biofilm-mediated virulence, multidrug resistance, clinical impact, and emerging treatment strategies: A review

Biomolecules & Biomedicine
Stenotrophomonas maltophilia is an opportunistic, multidrug-resistant (MDR), Gram-negative bacterium that has emerged as an important cause of hospital- and community-acquired infections, particularly in immunocompromised, critically ill, and ...
Noha A. Juma, Ahmed Gassim Bukhari, Turki M. Alharthi, Ibrahim Abu, Khalid Ahmed, Mohammad Hassan Albar, Ziyad Omar Allehebi, Turki Asiri, Salem Agabawi, Sarah Almuhayya, Khalil Alkuwaity, Dalya Attallah, Jawahir A. Mokhtar, Tariq Ekhmimi, Abdelbagi Alfadil, Bandar Hasan Saleh, Mona Alqarni, Noura Daffa, Karem Ibrahem   +18 more
doaj   +1 more source

Antibacterial and Antifungal Activity of Ceragenins, Mimics of Endogenous Antimicrobial Peptides

, 2019
The continuous emergence of drug-resistance pathogens is a global concern. As a result, substantial effort is being expended to develop new therapeutics and mechanisms for controlling microbial growth to avoid entering a post-antibiotic era in which ...
Mohammadihashemi, Marjan
core  

Application and Development of Ceragenins in Medical Device Coatings for Clinical Settings [PDF]

Hospital-acquired infections (HAIs) pose a significant and increasing threat to global health. One primary cause of this threat is increasing antibiotic resistance.
Sherren, Elliot E.
core  

Antifungal susceptibilities, in vitro production of virulence factors and activities of ceragenins against Candida spp. isolated from vulvovaginal candidiasis

, 2018
Vulvovaginal candidiasis (VVC) is the second most common cause of vaginitis after bacterial vaginosis, affecting millions of women worldwide every year.
Guzel, Cagla Bozkurt, SAVAGE, Paul B., Hacioglu, MAYRAM, Paul B Savage, A Seher Birteksoz Tan, Tan, A. Seher Birteksoz, Mayram Hacioglu, Cagla Bozkurt Guzel   +7 more
core   +1 more source

Targeting polyelectrolyte networks in purulent body fluids to modulate bactericidal properties of some antibiotics

Infection and Drug Resistance, 2018
Robert Bucki,1,* Bonita Durnaś,2,* Marzena Wątek,2,3 Ewelina Piktel,1 Katrina Cruz,4 Przemysław Wolak,2 Paul B Savage,5 Paul A Janmey4 1Department of Microbiological and Nanobiomedical Engineering, Medical University of Białystok, Białystok, 2Department ...
Bucki R, Durnaś B, Wątek M, Piktel E, Cruz K, Wolak P, Savage PB, Janmey PA   +7 more
doaj  

Effects of ceragenins and conventional antimicrobials on Candida albicans and Staphylococcus aureus mono and multispecies biofilms

, 2019
It is known that synergy between Candida albicans and Staphylococcus aureus results in enhanced biofilm formation and increased resistance to antimicrobials.
Bozkurt-Guzel, Cagla, Hacioglu, Mayram, Birteksoz-Tan, Ayse Seher, HACIOSMANOĞLU, EBRU, Savage, Paul B., BOZKURT GÜZEL, Çağla, BİRTEKSÖZ TAN, Ayşe Seher   +6 more
core   +1 more source

Exploring the role of cathelicidin LL-37 and ceragenins in wound healing processes

European Journal of Pharmacology
Wound healing and tissue regeneration are essential for maintaining skin integrity in the face of mechanical, chemical, or thermal damage. In adult mammals, the wound healing process may include complications leading to chronic wounds and hypertrophic scars.
Łuckiewicz, Milena, Urszula Wnorowska, Zakrzewska, Magdalena, Błażejczyk, Idalia, Tamara Daniluk, Kondziołka, Wioleta, Savage, Paul, Robert Bucki, Ewelina Piktel   +8 more
openaire   +3 more sources

Table_1_Proteomic Analysis of Resistance of Gram-Negative Bacteria to Chlorhexidine and Impacts on Susceptibility to Colistin, Antimicrobial Peptides, and Ceragenins.XLSX

, 2019
Use of chlorhexidine in clinical settings has led to concerns that repeated exposure of bacteria to sub-lethal doses of chlorhexidine might result in chlorhexidine resistance and cross resistance with other cationic antimicrobials including colistin ...
Marjan M. Hashemi (6372485), Scott Weber (6372497), Aaron L. Zaugg (6372503), Colten McEwan (6372506), John C. Price (1718788), Brett S. Holden (6372488), Joshua L. Andersen (6372509), Maddison F. Taylor (6372494), Brian Hilton (6372500), Paul B. Savage (178014), Richard Carson (3765340), Jordan Coburn (6372491), Shenglou Deng (1897018)   +12 more
core   +1 more source

Incorporating Ceragenins into Coatings Protects Peripherally Inserted Central Catheter Lines against Pathogen Colonization for Multiple Weeks. [PDF]

Int J Mol Sci, 2023
Zaugg A, Sherren E, Yi R, Larsen T, Dyck B, Stump S, Pauga F, Linder A, Takara M, Gardner E, Shin S, Pulsipher J, Savage PB.   +12 more
europepmc   +1 more source