Results 41 to 50 of about 82,164 (300)
Detergent-Resistant, Ceramide-Enriched Domains in Sphingomyelin/Ceramide Bilayers [PDF]
Biophysical Journal, 2006 When cell membranes are treated with Triton X-100 or other detergents at 4 degrees C, a nonsolubilized fraction can often be recovered, the "detergent-resistant membranes", that is not found when detergent treatment takes place at 37 degrees C. Detergent-resistant membranes may be related in some cases to membrane "rafts".
Sot, Jesus +3 more
openaire +5 more sources
A simple, highly sensitive, and facile method to quantify ceramide at the plasma membrane
Journal of Lipid Research, 2023 The role of ceramide in biological functions is typically based on the elevation of cellular ceramide, measured by LC-MS in the total cell lysate. However, it has become increasingly appreciated that ceramide in different subcellular organelles regulates
Meaghan Greene +4 more
doaj +1 more source
Cell Metabolism, 2018 Mutations in PLA2G6 (PARK14) cause neurodegenerative disorders in humans, including autosomal recessive neuroaxonal dystrophy and early-onset parkinsonism.
Guang Lin +8 more
semanticscholar +1 more source
Developmental Comparison of Ceramide in Wild-Type and Cln3Δex7/8 Mouse Brains and Sera
Frontiers in Neurology, 2019 CLN3 disease is a neurodevelopmental disease leading to early visual failure, motor decline, and death. CLN3 pathogenesis has been linked to dysregulation of ceramide, a key intracellular messenger impacting various biological functions.
Sally El-Sitt +6 more
doaj +1 more source
Ceramide Remodeling and Risk of Cardiovascular Events and Mortality
Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2018 Background Recent studies suggest that circulating concentrations of specific ceramide species may be associated with coronary risk and mortality. We sought to determine the relations between the most abundant plasma ceramide species of differing acyl ...
L. Peterson +14 more
semanticscholar +1 more source
Separation of neutral glycosphingolipids and sulfatides by thin-layer chromatography
Journal of Lipid Research, 1967 Two one-dimensional systems for separation of glycolipids from total lipid extracts of tissues by thin-layer chromatography are described. System I used, as adsorbent, an alkaline mixture of silica gel without CaSO4 binder (75%) and magnesium silicate ...
Vladimir P. Skipski +2 more
doaj +1 more source
Ecotoxicology and Environmental Safety, 2021 Studies about radiation damage in vivo are very significant for healthy risk assessment as well as cancer radiotherapy. Ceramide as a second messenger has been found to be related to radiation-induced apoptosis. However, the detailed mechanisms in living
Yaning Yang +6 more
doaj +1 more source
Characterization of neutral sphingolipids from chicken erythrocytes.
Journal of Lipid Research, 1985 The neutral sphingolipids from chicken erythrocytes were characterized. The total concentration of neutral sphingolipids was found to be 480 nmol/g of dry stroma.
T Shiraishi, Y Uda
doaj +1 more source
Cell Reports, 2021 Summary: We lack a mechanistic understanding of aging-mediated changes in mitochondrial bioenergetics and lipid metabolism that affect T cell function.
Silvia Vaena +14 more
doaj +1 more source
Ceramide kinase uses ceramide provided by ceramide transport protein: localization to organelles of eicosanoid synthesis [PDF]
Journal of Lipid Research, 2007 Ceramide kinase (CERK) is a critical mediator of eicosanoid synthesis, and its product, ceramide-1-phosphate (C1P), is required for the production of prostaglandins in response to several inflammatory agonists. In this study, mass spectrometry analysis disclosed that the main forms of C1P in cells were C(16:0) C1P and C(18:0) C1P, suggesting that CERK ...
Nadia F. Lamour +8 more
openaire +3 more sources