Results 11 to 20 of about 23,863 (196)

Neutral Ceramidase Is Required for the Reproduction of Brown Planthopper, Nilaparvata lugens (Stål)

Frontiers in Physiology, 2021
Ceramides are bioactive sphingolipids that have been implicated in insect development; however, their role in insect reproduction remains poorly understood.
Xiao-Xiao Shi, Mu-Fei Zhu, Ni Wang, Yuan-Jie Huang, Yuan-Jie Huang, Min-Jing Zhang, Chao Zhang, Soomro A. Ali, Wen-Wu Zhou, Chuanxi Zhang, Cungui Mao, Zeng-Rong Zhu, Zeng-Rong Zhu   +12 more
doaj   +1 more source

The Role of Ceramides in Diabetes and Cardiovascular Disease Regulation of Ceramides by Adipokines

Frontiers in Endocrinology, 2020
Metabolic dysfunction is intertwined with the pathophysiology of both diabetes and cardiovascular disease. Recently, one particular lipid class has been shown to influence the development and sustainment of these diseases: ceramides.
Bianca C. Field, Ruth Gordillo, Philipp E. Scherer, Philipp E. Scherer   +3 more
doaj   +1 more source

Blood-brain barrier permeability analysis of plant ceramides.

PLoS ONE, 2020
Ceramides, a type of sphingolipid, are cell membrane components and lipid mediators that modulate a variety of cell functions. In plants, ceramides are mostly present in a glucosylated glucosylceramide (GlcCer) form.
Koichi Eguchi, Daisuke Mikami, Hui Sun, Takuya Tsumita, Kaori Takahashi, Katsuyuki Mukai, Kohei Yuyama, Yasuyuki Igarashi   +7 more
doaj   +1 more source

Targeting Ceramides and Adiponectin Receptors in the Islet of Langerhans for Treating Diabetes

Molecules, 2022
Ceramides belong to the sphingolipid family and represent the central hub of the sphingolipid network. In obesity, oversupply of saturated fatty acids including palmitate raises ceramide levels which can be detrimental to cells.
Wen-hong Li
doaj   +1 more source

Identification and quantitation of free ceramides in human platelets

Journal of Lipid Research, 1972
Free ceramides were isolated from human platelets. Their structures were unequivocally determined by gas–liquid chromatography–mass spectrometry of the trimethylsilyl ether derivatives.
William Krivit, Sven Hammarström
doaj   +1 more source

Ceramides and phospholipids in plasma extracellular vesicles are associated with high risk of major cardiovascular events after carotid endarterectomy

Scientific Reports, 2022
Ceramides and phosphatidylcholines (PCs) are bioactive lipids and lipid bilayer membrane components. Distinct ceramides/PCs (ratios) predict cardiovascular outcome in patients with coronary artery disease.
Nathalie Timmerman, Farahnaz Waissi, Mirthe Dekker, Gert J. de Borst, Joelle van Bennekom, Robbert J. de Winter, Mika Hilvo, Antti Jylhä, Gerard Pasterkamp, Dominique P. V. de Kleijn, Reijo Laaksonen   +10 more
doaj   +1 more source

Whole picture of human stratum corneum ceramides, including the chain-length diversity of long-chain bases

Journal of Lipid Research, 2022
Ceramides are essential lipids for skin permeability barrier function, and a wide variety of ceramide species exist in the stratum corneum (SC). Although ceramides with long-chain bases (LCBs) of various lengths have been identified in the human SC, a ...
Madoka Suzuki, Yusuke Ohno, Akio Kihara
doaj   +1 more source

Fuse your mitochondria, lose appetite: an anorexic, anti‐obesity sphingolipid

EMBO Molecular Medicine, 2021
Aberrant production of ceramides, the precursors of complex sphingolipids, is a hallmark of obesity and strongly linked to metabolic dysfunction (Meikle and Summers 2017).
Carolin Muley, Alexander Bartelt
doaj   +1 more source

Lipidomic Analysis to Assess the Correlation between Ceramides, Stress Hyperglycemia, and HbA1c in Acute Myocardial Infarction

Molecules, 2023
Ceramides have been associated with cardiometabolic disease (e.g., acute myocardial infarction (AMI) and type 2 diabetes (T2D)) and adverse outcomes. Acute admission hyperglycemia (AH) is a transient glucose alteration in response to stress.
Melania Gaggini, Elena Michelucci, Rudina Ndreu, Silvia Rocchiccioli, Kyriazoula Chatzianagnostou, Sergio Berti, Cristina Vassalle   +6 more
doaj   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source