Results 151 to 160 of about 459,917 (239)
Organoid-ICLIP: Class imbalance-aware vision-language learning for organoid mitosis classification
Visual analysis of brain organoid imaging is critical for advancing the understanding of in vitro organoid development. However, precise differentiation of mitotic stages remains challenging due to complex cellular morphology and limited imaging data. To
Anabia Sohail (22171822) +2 more
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Characterization of extracellular vesicles and miRNA released by cerebral organoids
Current Research in ToxicologyEnvironmental toxicants can contribute to the development of several neurodegenerative diseases. However, the mechanisms behind this pathology are still incompletely understood. Prompt diagnosis of impending neurodegeneration is crucial for early interventions to prevent cognitive decline.
Brian B. Silver +3 more
openaire +3 more sources
The Journal of Physiology, EarlyView.Abstract figure legend This study assessed the impact of plasma‐derived small extracellular vesicles (sEVs) from healthy pregnant women and those diagnosed with late‐onset preeclampsia (PE) on the blood–brain barrier (BBB) integrity and glial cell response. PE patients had higher sEV concentrations than healthy controls.
Julián Henao‐Restrepo +7 more
wiley +1 more source
Inclusión sociolaboral de personas con Daño Cerebral Adquirido (DCA) [PDF]
, 2020 Para impulsar la promoción de la autonomía personal de las personas con DCA, FEDACE retoma la experiencia formativa de los Talleres FEDACE sobre Daño Cerebral como “una apuesta por la divulgación del conocimiento sobre el Daño Cerebral”, el enfoque ...
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Microglial Labeling in Mouse Spinal Cord Injury: A Review of Timing, Efficacy, and Specificity
Glia, Volume 74, Issue 12, December 2026.The transcriptional profile of microglia is significantly altered after spinal cord injury (SCI). When choosing a marker to label microglia after SCI, it is important to consider its specificity for microglia and its stability of expression. ABSTRACT Traumatic spinal cord injury (SCI) is a complex and disabling condition with no curative therapy ...
Ruth Colbert +2 more
wiley +1 more source
Establishing Area-Specific Brain Organoids Through Transcription Factor-Mediated Patterning
BiologyThe human cerebral cortex is organized into distinct area-specific regions along the rostral–caudal axis, yet current human brain organoid models incompletely recapitulate this regional diversity.
Jonghun Kim +6 more
doaj +1 more source
AI Alignment Versus AI Ethical Treatment: 10 Challenges
Analytic Philosophy, Volume 67, Issue 4, Page 309-327, December 2026.ABSTRACT A morally acceptable course of AI development should avoid two dangers: creating unaligned AI systems that pose a threat to humanity and mistreating AI systems that merit moral consideration in their own right. This paper argues these two dangers interact and that if we create AI systems that merit moral consideration, simultaneously avoiding ...
Adam Bradley, Bradford Saad
wiley +1 more source
Advanced Materials for Biologics Delivery to Brain Tumors
Advanced Materials, Volume 38, Issue 61, 2 November 2026.Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
Building Immunocompetent Cerebral Organoids From a Developmental Perspective
GliaABSTRACTCerebral organoids derived from human induced pluripotent stem cells (iPSCs) are increasingly becoming essential tools to study the human brain, from understanding pathological mechanisms in neurodevelopmental, neurodegenerative, and infectious diseases to identifying genetic risks and biomarkers.
Cuesta‐Puente, Xabier +8 more
openaire +3 more sources