Results 51 to 60 of about 28,293 (248)

High-throughput validation of ceRNA regulatory networks

open access: yesBMC Genomics, 2017
Background: MicroRNAs (miRNAs) play multiple roles in tumor biology [1]. Interestingly, reports from multiple groups suggest that miRNA targets may be coupled through competitive stoichiometric sequestration [2]. Specifically, computational models predicted [3, 4] and experimental assays confirmed [5, 6] that miRNA activity is dependent on miRNA target
Hua-Sheng Chiu   +7 more
openaire   +4 more sources

Long Noncoding RNA LINC01426 Sequesters microRNA-519d-5p to Promote Non-Small Cell Lung Cancer Progression by Increasing ETS1 Expression [Expression of Concern]

open access: yesCancer Management and Research, 2021
Dai J, Wang B, Zhao Y, et al. Cancer Manag Res. 2020;12:12697–12708. The Editor and Publisher of Cancer Management and Research wish to publish an Expression of Concern for the published article.
Dai J   +6 more
doaj  

Research progress of long non-coding RNA in cutaneous squamous cell carcinoma

open access: yesPifu-xingbing zhenliaoxue zazhi, 2022
Cutaneous squamous cell carcinoma (cSCC) is one of the most common types of skin cancer. The incidence of the skin cancer is increasing year by year and seriously affects the quality of life of patients.
Xianwen LI   +7 more
doaj   +1 more source

TET3‐Mediated m5C Modification of CCAT2 Accelerates Cardiac Microvascular Endothelial Cell Damage in Acute Coronary Syndrome

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Acute coronary syndrome (ACS) is a clinical syndrome involving myocardial ischemia. This study aimed to elucidate the mechanism of TET3 in ACS‐induced CMEC damage, thereby identifying a new target for ACS treatment. The expression of TET3 in ACS patients and healthy subjects was analyzed.
Jun‐Cheng Liu   +5 more
wiley   +1 more source

Analysis of lncRNA-miRNA-mRNA Expression in the Troxerutin-Mediated Prevention of Radiation-Induced Lung Injury in Mice

open access: yesJournal of Inflammation Research, 2023
Nan Zhang,1,* Gui-yuan Song,2,3,* Yong-jian Hu,4 Xia Wang,4 Tian-zhu Chao,1 Yao-yao Wu,1 Ping Xu1 1School of Food and Biomedicine, Zaozhuang University, Zaozhuang, Shandong, 277160, People’s Republic of China; 2School of Public Health, Weifang ...
Zhang N   +6 more
doaj  

Circ_0006174 Drives Triple Negative Breast Cancer Progression and Immune Escape Through Regulating miR‐3139/PD‐L1 Axis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) is characterized as an aggressive malignancy with limited therapeutic options. The circular RNA circ_0006174 has been implicated in oncogenic processes across various cancers; however, its specific role in the pathogenesis of TNBC remains unclear.
Yong‐Zhe Tang   +4 more
wiley   +1 more source

Silencing of LINC00707 suppresses cell proliferation, migration, and invasion of osteosarcoma cells by modulating miR-338-3p/AHSA1 axis

open access: yesOpen Life Sciences, 2021
Osteosarcoma is the most common type of primary malignant tumor of the bone, with a high metastatic rate and poor prognosis. Therefore, it is important to further elucidate the molecular mechanisms involved in the development of osteosarcoma and explore ...
Zhang Xiao-rong   +3 more
doaj   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto   +2 more
wiley   +1 more source

Beban Candida dalam Saluran Cerna Anak

open access: yesMajalah Kedokteran UKI, 2021
AbstrakMikrobiota terbesar pada tubuh manusia terdapat pada saluran cerna (70%).Mikrobiota normal saluran cerna tersusun atas komposisi mikroorganisme yang unik dan berada dalam keadaan seimbang, didalamnya termasuk Candidaspp., yang hidup sebagai komensal.
Hardi Hutabarat   +3 more
openaire   +2 more sources

Long Non-Coding RNA LINC01783 Promotes the Progression of Cervical Cancer by Sponging miR-199b-5p to Mediate GBP1 Expression

open access: yesCancer Management and Research, 2020
Wei-jun Chen, 1,* Liang Xiong, 2,* Lin Yang, 3 Li-juan Yang, 3 Lin Li, 3 Li Huang, 3 Xiao-qing Liang, 4 Jie Xue, 3 Bu-zhen Tan 5 1Department of Gynaecology and Obstetrics, The Second Affiliated Hospital of Nanchang University, Reproductive Hospital ...
Chen W   +8 more
doaj  

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