Results 1 to 10 of about 17,535 (240)

Identification of a circRNA-mediated immune-related ceRNA network and circRNAs as diagnostic biomarkers in acute ischemic stroke [PDF]

European Journal of Medical Research
Background Research has demonstrated that circular RNAs (circRNAs) play important roles in acute ischemic stroke (AIS). However, the functions of circRNA-mediated competitive endogenous RNA (ceRNA) in AIS-related immunological inflammation are not well ...
Hongxiang Jiang, Peidong He, Shishi Chen, Jiangrui Zhu, Maorui Yi, Qianxue Chen, Yanping Zeng, Qiang Cai   +7 more
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Uncovering the ceRNA network and DNA methylation associated with gene expression in nasopharyngeal carcinoma

BMC Medical Genomics, 2023
Objective This study aimed to uncover abnormally expressed genes regulated by competitive endogenous RNA (ceRNA) and DNA methylation nasopharyngeal carcinoma and to validate the role of lncRNAs in the ceRNA network on nasopharyngeal carcinoma progression.
Ting Zhang, Lu Pei, Wen-Li Qiu, Yu-xia Wei, Bi-yun Liao, Feng-lian Yang   +5 more
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Identification and functional analysis of a three-miRNA ceRNA network in hypertrophic scars

Journal of Translational Medicine, 2021
Background Hypertrophic scar (HTS) is a fibrotic disorder of skins and may have repercussions on the appearance as well as functions of patients. Recent studies related have shown that competitive endogenous RNA (ceRNA) networks centering around miRNAs ...
Zewei Zhang, Xin Huang, Jiahao Yang, Shuchen Gu, Yixuan Zhao, Yunhan Liu, Yimin Khoong, Shuqi Wang, Shenying Luo, Tao Zan, Guangshuai Li   +10 more
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Biomarkers mining for spinal cord injury based on integrated multi-transcriptome expression profile data

Journal of Orthopaedic Surgery and Research, 2021
Background This study was aimed to discover more biomarkers associated with spinal cord injury (SCI) by constructing a competing endogenous RNA (ceRNA) network.
Chongcheng Gong, Lin Liu, Yang Shen
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Bioinformatics-Based Analysis of the lncRNA-miRNA-mRNA Network and TF Regulatory Network to Explore the Regulation Mechanism in Spinal Cord Ischemia/Reperfusion Injury

Frontiers in Genetics, 2021
BackgroundSpinal cord ischemia/reperfusion injury (SCII) is a catastrophic complication involved with cardiovascular, spine, and thoracic surgeries and can lead to paraplegia.
Dan Wang, Limei Wang, Jie Han, Zaili Zhang, Bo Fang, Fengshou Chen   +5 more
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Integrated analysis of the lncRNA-associated competing endogenous RNA network in salt sensitivity of blood pressure

Heliyon, 2023
Accumulating evidence showed that competing endogenous RNA (ceRNA) mechanism plays a pivotal role in salt sensitivity of blood pressure (SSBP). We constructed a ceRNA network based on SSBP-related differently expressed lncRNAs (2), mRNAs (73) and miRNAs (
Wenjuan Peng, Yunyi Xie, Juan Xia, Han Qi, Kuo Liu, Bingxiao Li, Fengxu Zhang, Fuyuan Wen, Ling Zhang   +8 more
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Establishment and analysis of the lncRNA-miRNA-mRNA network based on competitive endogenous RNA identifies functional genes in heart failure

Mathematical Biosciences and Engineering, 2021
Heart failure (HF), a common disease in adults, accounts for significantly global morbidity and mortality. Due to population aging, therapeutic progression in acute cardiovascular events, the prevalence of HF is increasing, in spite of the efficacy of ...
Xudan Ma, Qijun Zhang, Haihong Zhu, Kefeng Huang, Weina Pang , Qin Zhang   +5 more
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A New Strategy to Identify ceRNA-Based CCDC144NL-AS1/SERPINE1 Regulatory Axis as a Novel Prognostic Biomarker for Stomach Adenocarcinoma via High Throughput Transcriptome Data Mining and Computational Verification

Frontiers in Oncology, 2022
Stomach adenocarcinoma (STAD) is one of the most malignant cancers that endanger human health. There is growing evidence that competitive endogenous RNA (ceRNA) regulatory networks play an important role in various human tumors.
Zhihong Huang, Xinkui Liu, Chao Wu, Shan Lu, Stalin Antony, Wei Zhou, Jingyuan Zhang, Zhishan Wu, Yingying Tan, Xiaotian Fan, Leiming You, Zhiwei Jing, Jiarui Wu   +12 more
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Identifying a Comprehensive ceRNA Network to Reveal Novel Targets for the Pathogenesis of Parkinson's Disease

Frontiers in Neurology, 2020
Parkinson's disease (PD) is the second commonest progressive neurodegenerative disease worldwide. Increasing evidence reveals that non-coding RNAs play roles in the pathophysiological process of PD.
Xi Zhang, Xi Zhang, Shengyu Feng, Yu Fan, Yuping Luo, Lingjing Jin, Siguang Li, Siguang Li, Siguang Li   +8 more
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Identification of functional lncRNAs through constructing a lncRNA-associated ceRNA network in myocardial infarction

Mathematical Biosciences and Engineering, 2021
Myocardial infarction (MI) is a type of coronary heart disease, which refers to the ischemic necrosis of the heart muscle. A large number of studies have discussed the mechanism of MI from the perspective of competing endogenous RNA (ceRNA) network ...
Beibei Zhu, Yue Mao, Mei Li
doaj   +1 more source