Results 1 to 10 of about 6,111,011 (310)

Systematic Characterization of Circular RNA-Associated CeRNA Network Identified Novel circRNA Biomarkers in Alzheimer's Disease [PDF]

open access: goldFrontiers in Bioengineering and Biotechnology, 2019
Alzheimer's disease (AD), a degenerative disease of the central nervous system, is the most common form of dementia in old age. The complexity and behavior of circular RNA (circRNA)-associated competing endogenous RNA (ceRNA) network remained poorly ...
Yan Zhang, Fulong Yu, Siqi Bao, Jie Sun
doaj   +2 more sources

Prognostic Roles of ceRNA Network-Based Signatures in Gastrointestinal Cancers

open access: yesFrontiers in Oncology, 2022
Gastrointestinal cancers (GICs) are high-incidence malignant tumors that seriously threaten human health around the world. Their complexity and heterogeneity make the classic staging system insufficient to guide patient management.
Xin Qi   +6 more
doaj   +2 more sources

Construction and analysis of pseudogene-related ceRNA network in breast cancer. [PDF]

open access: yesSci Rep, 2023
Breast cancer (BC) is one of the leading causes of cancer-related deaths in women. The present study explored the potential role of pseudogenes in BC via construction and analysis of a competing endogenous RNA (ceRNA) network through a three-step process.
Mohebifar H   +3 more
europepmc   +2 more sources

STARD13-correlated ceRNA network-directed inhibition on YAP/TAZ activity suppresses stemness of breast cancer via co-regulating Hippo and Rho-GTPase/F-actin signaling

open access: yesJournal of Hematology & Oncology, 2018
Background Targeting cancer stem cells is critical for suppressing cancer progression and recurrence. Finding novel markers or related pathways could help eradicate or diagnose cancer in clinic.
Lufeng Zheng   +7 more
doaj   +2 more sources

Circular RNA-related CeRNA network and prognostic signature for patients with oral squamous cell carcinoma

open access: yesFrontiers in Pharmacology, 2022
Background: Circular RNA (circRNA) has an important influence on oral squamous cell carcinoma (OSCC) progression as competing endogenous RNAs (ceRNAs). However, the link between ceRNAs and the OSCC immune microenvironment is unknown.
Yaodong He   +5 more
doaj   +2 more sources

Identification and validation of a novel glycolysis-related ceRNA network for sepsis-induced cardiomyopathy [PDF]

open access: yesFrontiers in Medicine
PurposeSepsis-induced cardiomyopathy (SIC) is a major life-threatening condition in critically infected patients. Early diagnosis and intervention are important to improve patient prognosis.
Lulu Cheng   +7 more
doaj   +2 more sources

Comprehensive analysis of lncRNA-miRNA-mRNA ceRNA network in ischemic stroke [PDF]

open access: yesHeliyon
Objective: Competitive endogenous RNA (ceRNA) networks have uncovered a novel mode of RNA interaction, and are implicated in various biological processes and the pathogenesis of IS.
Lin Cheng, Yun Zhao, Hong Ke
doaj   +2 more sources

Identification of a circRNA-mediated immune-related ceRNA network and circRNAs as diagnostic biomarkers in acute ischemic stroke [PDF]

open access: yesEuropean Journal of Medical Research
Background Research has demonstrated that circular RNAs (circRNAs) play important roles in acute ischemic stroke (AIS). However, the functions of circRNA-mediated competitive endogenous RNA (ceRNA) in AIS-related immunological inflammation are not well ...
Hongxiang Jiang   +7 more
doaj   +2 more sources

Comprehensive analysis of PRPF19 immune infiltrates, DNA methylation, senescence-associated secretory phenotype and ceRNA network in bladder cancer

open access: yesFrontiers in Immunology, 2023
Background Pre-mRNA processing factor 19 (PRPF19) is an E3 ligase that plays a crucial role in repairing tumor-damaged cells and promoting cell survival.
YaXuan Wang   +7 more
semanticscholar   +1 more source

Comprehensive analysis of FOXM1 immune infiltrates, m6a, glycolysis and ceRNA network in human hepatocellular carcinoma

open access: yesFrontiers in Immunology, 2023
Background Forkhead box M1 (FOXM1) is a member of the Forkhead box (Fox) transcription factor family. It regulates cell mitosis, cell proliferation, and genome stability.
Zi-Heng Xu   +12 more
semanticscholar   +1 more source

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