Results 1 to 10 of about 6,111,011 (310)
Systematic Characterization of Circular RNA-Associated CeRNA Network Identified Novel circRNA Biomarkers in Alzheimer's Disease [PDF]
Alzheimer's disease (AD), a degenerative disease of the central nervous system, is the most common form of dementia in old age. The complexity and behavior of circular RNA (circRNA)-associated competing endogenous RNA (ceRNA) network remained poorly ...
Yan Zhang, Fulong Yu, Siqi Bao, Jie Sun
doaj +2 more sources
Prognostic Roles of ceRNA Network-Based Signatures in Gastrointestinal Cancers
Gastrointestinal cancers (GICs) are high-incidence malignant tumors that seriously threaten human health around the world. Their complexity and heterogeneity make the classic staging system insufficient to guide patient management.
Xin Qi+6 more
doaj +2 more sources
Construction and analysis of pseudogene-related ceRNA network in breast cancer. [PDF]
Breast cancer (BC) is one of the leading causes of cancer-related deaths in women. The present study explored the potential role of pseudogenes in BC via construction and analysis of a competing endogenous RNA (ceRNA) network through a three-step process.
Mohebifar H+3 more
europepmc +2 more sources
Background Targeting cancer stem cells is critical for suppressing cancer progression and recurrence. Finding novel markers or related pathways could help eradicate or diagnose cancer in clinic.
Lufeng Zheng+7 more
doaj +2 more sources
Background: Circular RNA (circRNA) has an important influence on oral squamous cell carcinoma (OSCC) progression as competing endogenous RNAs (ceRNAs). However, the link between ceRNAs and the OSCC immune microenvironment is unknown.
Yaodong He+5 more
doaj +2 more sources
Identification and validation of a novel glycolysis-related ceRNA network for sepsis-induced cardiomyopathy [PDF]
PurposeSepsis-induced cardiomyopathy (SIC) is a major life-threatening condition in critically infected patients. Early diagnosis and intervention are important to improve patient prognosis.
Lulu Cheng+7 more
doaj +2 more sources
Comprehensive analysis of lncRNA-miRNA-mRNA ceRNA network in ischemic stroke [PDF]
Objective: Competitive endogenous RNA (ceRNA) networks have uncovered a novel mode of RNA interaction, and are implicated in various biological processes and the pathogenesis of IS.
Lin Cheng, Yun Zhao, Hong Ke
doaj +2 more sources
Identification of a circRNA-mediated immune-related ceRNA network and circRNAs as diagnostic biomarkers in acute ischemic stroke [PDF]
Background Research has demonstrated that circular RNAs (circRNAs) play important roles in acute ischemic stroke (AIS). However, the functions of circRNA-mediated competitive endogenous RNA (ceRNA) in AIS-related immunological inflammation are not well ...
Hongxiang Jiang+7 more
doaj +2 more sources
Background Pre-mRNA processing factor 19 (PRPF19) is an E3 ligase that plays a crucial role in repairing tumor-damaged cells and promoting cell survival.
YaXuan Wang+7 more
semanticscholar +1 more source
Background Forkhead box M1 (FOXM1) is a member of the Forkhead box (Fox) transcription factor family. It regulates cell mitosis, cell proliferation, and genome stability.
Zi-Heng Xu+12 more
semanticscholar +1 more source