Results 11 to 20 of about 6,111,011 (310)
Comprehensive ceRNA network for MACF1 regulates osteoblast proliferation
BMC Genomics, 2022 Background Previous studies have shown that microtubule actin crosslinking factor 1 (MACF1) can regulate osteoblast proliferation and differentiation through non-coding RNA (ncRNA) in bone-forming osteoblasts.
Shanfeng Jiang +5 more
semanticscholar +4 more sources
Tamoxifen resistance-related ceRNA network for breast cancer
Frontiers in Cell and Developmental Biology, 2022 Background: Tamoxifen (TMX) is one of the most widely used drugs to treat breast cancer (BC). However, acquired drug resistance is still a major obstacle to its application, rendering it crucial to explore the mechanisms of TMX resistance in BC.
Zipeng Qiao +5 more
semanticscholar +4 more sources
Integrated Analysis of lncRNA–Mediated ceRNA Network in Lung Adenocarcinoma [PDF]
Frontiers in Oncology, 2020 Background A growing body of evidence indicates that long non-coding RNAs (lncRNAs) can act as competitive endogenous RNAs (ceRNAs) to bind to microRNAs (miRNAs), thereby affecting and regulating the expression of target genes.
Xian-xian Wu +4 more
semanticscholar +5 more sources
Development of Ferroptosis-Associated ceRNA Network in Periodontitis
International Dental Journal, 2022 Periodontitis is a chronic inflammatory illness that may lead to tooth loosening and even loss, and its pathogenesis is not fully understood. Ferroptosis is an iron-dependent, regulated cell death. The present study aims to find the key ferroptosis-related genes (FRGs) in periodontitis and develop an mRNA-miRNA-lncRNA network to deeply explore the ...
Churen Zhang +3 more
semanticscholar +4 more sources
lncRNA-mediated ceRNA network in bladder cancer
Non-coding RNA Research, 2022 Bladder cancer is a common disease associated with high rates of morbidity and mortality. Although immunotherapy approaches such as adoptive T-cell therapy and immune checkpoint blockade have been investigated for the treatment of bladder cancer, their off-target effects and ability to affect only single targets have led to clinical outcomes that are ...
Kun Li, Tongyue Yao, Ziqiang Wang
semanticscholar +4 more sources
Construction and dissection of the ceRNA‑ceRNA network reveals critical modules in depression
Molecular Medicine Reports, 2019 The prevalence of mental health disorders such as depression is high. Depression is a multifactorial disorder and its underlying mechanisms remain unclear. Competing endogenous RNA (ceRNA) regulation has been reported to serve important roles in human disease.
Lang Yan, Jingchao Zhang, Zheng Wei Yuan
openalex +5 more sources
Chemoresistance Mediated by ceRNA Networks Associated With the PVT1 Locus [PDF]
Frontiers in Oncology, 2019 Competitive endogenous RNA (ceRNA) networks have emerged as critical regulators of carcinogenesis. Their activity is mediated by various non-coding RNAs (ncRNAs), including long non-coding RNAs and microRNAs, which competitively bind to targets, thereby modulating gene expression and activity of proteins.
Olorunseun O. Ogunwobi, Adithya Kumar
openalex +4 more sources
Deciphering the rules of ceRNA networks [PDF]
Proceedings of the National Academy of Sciences, 2013 Recent theoretical and experimental studies have shed light on the complex network of interactions among the multiple classes of RNA within the cell. Although much of the focus over the past decade has been on the mechanisms by which microRNAs (miRNA) regulate the stability and translation of messenger RNAs (mRNAs), more recently it has come to light ...
George Q. Daley, Marcella Cesana
openaire +5 more sources
Analysis of a circRNA-, miRNA-, and mRNA-associated ceRNA network reveals potential biomarkers in preeclampsia a ceRNA network in preeclampsia [PDF]
Annals of Medicine, 2021 Preeclampsia (PE), one of hypertension-related disorders of pregnancy, is a common cause of maternal death worldwide. This study aimed to identify a circRNA-miRNA-mRNA-associated ceRNA network and related pathways in PE. We downloaded 3 microarray datasets from the Gene Expression Omnibus database, obtained 163 differentially expressed circRNAs (dif ...
Xiaoxiao Xu, Sha Lv, Ziwen Xiao
openaire +3 more sources
Journal of Nanobiotechnology, 2023 Purpose Endothelial cell dysfunction is a major cause of early atherosclerosis. Although the role of extracellular vesicles in stabilizing atherosclerotic plaques is well established, the effect of circulating exosomes on plaque formation is still ...
Xiao Tong +13 more
semanticscholar +1 more source