Results 21 to 30 of about 6,111,011 (310)
Construction of ceRNA regulatory networks for osteoporosis
Molecular Medicine Reports, 2023 Osteoporosis increases the risk of fracture. Improving the diagnosis and treatment of osteoporosis has clinical applications. The differentially expressed genes (DEcircRs, DEmRs, DEmiRs) of osteoporotic patients and controls were analyzed using the GEO database, and enrichment analysis of DEmRs was performed. circRNAs and mRNAs, which were predicted to
Chen, Hongtao +5 more
openaire +2 more sources
Identification of a lncRNA/circRNA-miRNA-mRNA ceRNA Network in Alzheimer's Disease.
Journal of Integrative Neuroscience, 2023 BACKGROUND Alzheimer's disease (AD) occurs in the elderly and pre-elderly, characterized by decline of memory, cognitive dysfunction, impairment of learning capacity, and motor dysfunction.
Li-ning Su +3 more
semanticscholar +1 more source
Clinical Cancer Research, 2023 Purpose: Sarcoma is the second most common solid tumor type in children and adolescents. The high level of tumor heterogeneity as well as aggressive behavior of sarcomas brings serious difficulties to developing effective therapeutic strategies for ...
D. Leng +9 more
semanticscholar +1 more source
The ceRNA network of lncRNA and miRNA in lung cancer [PDF]
Genomics & Informatics, 2020 Since lung cancer is a major causative for cancer-related deaths, the investigations for discovering biomarkers to diagnose at an early stage and to apply therapeutic strategies have been continuously conducted. Recently, long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) are being exponentially studied as promising biomarkers of lung cancer ...
Wanyeon Kim +3 more
openaire +3 more sources
LncRNA–miRNA–mRNA ceRNA network of different body colors in Plectropomus leopardus
Frontiers in Marine Science, 2023 Long non-coding RNAs (lncRNAs) play a multifaceted role in transcriptional regulation, and the potential molecular regulatory mechanisms of lncRNAs and lncRNA–miRNA–mRNA networks in body color formation are of great significance for its selective ...
Ruijuan Hao +6 more
semanticscholar +1 more source
BMC Medical Genomics, 2023 Objective This study aimed to uncover abnormally expressed genes regulated by competitive endogenous RNA (ceRNA) and DNA methylation nasopharyngeal carcinoma and to validate the role of lncRNAs in the ceRNA network on nasopharyngeal carcinoma progression.
Ting Zhang +5 more
doaj +1 more source
Bioinformatics analysis of lncRNA‑associated ceRNA network in melanoma [PDF]
Journal of Cancer, 2021 Melanoma is an extremely malignant tumor with early metastasis and high mortality. Little is known about the process of by which melanoma occurs, as its mechanism is very complex and only limited data are available on its long non-coding RNA (lncRNA)-associated competing endogenous RNAs (ceRNAs).
Long Chen +5 more
openaire +3 more sources
lncRNA–miRNA–mRNA ceRNA Network Involved in Sheep Prolificacy: An Integrated Approach
Genes, 2022 Understanding the molecular pattern of fertility is considered as an important step in breeding of different species, and despite the high importance of the fertility, little success has been achieved in dissecting the interactome basis of sheep ...
Masoumeh Sadeghi +7 more
semanticscholar +1 more source
Journal of Orthopaedic Surgery and Research, 2021 Background This study was aimed to discover more biomarkers associated with spinal cord injury (SCI) by constructing a competing endogenous RNA (ceRNA) network.
Chongcheng Gong, Lin Liu, Yang Shen
doaj +1 more source
Frontiers in Genetics, 2021 BackgroundSpinal cord ischemia/reperfusion injury (SCII) is a catastrophic complication involved with cardiovascular, spine, and thoracic surgeries and can lead to paraplegia.
Dan Wang +5 more
doaj +1 more source