Results 21 to 30 of about 17,535 (240)

Comprehensive ceRNA network for MACF1 regulates osteoblast proliferation

BMC Genomics, 2022
Abstract Background Previous studies have shown that microtubule actin crosslinking factor 1 (MACF1) can regulate osteoblast proliferation and differentiation through non-coding RNA (ncRNA) in bone-forming osteoblasts.
Shanfeng Jiang, Chong Yin, Kai Dang, Wenjuan Zhang, Ying Huai, Airong Qian   +5 more
openaire   +3 more sources

The Functional Characterization of Epigenetically Related lncRNAs Involved in Dysregulated CeRNA–CeRNA Networks Across Eight Cancer Types [PDF]

Frontiers in Cell and Developmental Biology, 2021
Numerous studies have demonstrated that lncRNAs could compete with other RNAs to bind miRNAs, as competing endogenous RNAs (ceRNAs), to regulate each other. On the other hand, ceRNAs were found to be recurrently dysregulated in cancer status. However, limited studies considered the upstream epigenetic regulatory factors that disrupted the normal ...
Dahua Xu, Liqiang Wang, Sainan Pang, Meng Cao, Wenxiang Wang, Xiaorong Yu, Zhizhou Xu, Jiankai Xu, Hong Wang, Jianping Lu, Kongning Li, Kongning Li   +11 more
openaire   +3 more sources

Tamoxifen resistance-related ceRNA network for breast cancer

Frontiers in Cell and Developmental Biology, 2022
Background: Tamoxifen (TMX) is one of the most widely used drugs to treat breast cancer (BC). However, acquired drug resistance is still a major obstacle to its application, rendering it crucial to explore the mechanisms of TMX resistance in BC. This aims of this study were to identify the mechanisms of TMX resistance and construct ceRNA regulatory ...
Zipeng Qiao, Zipeng Qiao, Yu Xing, Yu Xing, Qingquan Zhang, Qingquan Zhang, Yongjun Tang, Yongjun Tang, Ruifa Feng, Weiyi Pang, Weiyi Pang, Weiyi Pang   +11 more
openaire   +3 more sources

Analyzing the lncRNA, miRNA, and mRNA-associated ceRNA networks to reveal potential prognostic biomarkers for glioblastoma multiforme

Cancer Cell International, 2020
Background Glioblastoma multiforme (GBM) is the most seriously brain tumor with extremely poor prognosis. Recent research has demonstrated that competitive endogenous RNA (ceRNA) network which long noncoding RNAs (lncRNAs) act as microRNA (miRNA) sponges
Xiaolong Zhu, Lan Jiang, Hui Yang, Tianbing Chen, Xingwei Wu, Kun Lv   +5 more
doaj   +1 more source

Competing Endogenous RNA Network Analysis Reveals Pivotal ceRNAs in Adrenocortical Carcinoma

Frontiers in Endocrinology, 2019
Objective: To construct ceRNA network and identify pivotal competing endogenous RNAs (ceRNAs) in adrenocortical carcinoma (ACC) using ceRNA network analysis.Methods: The RNA sequencing expression data of 77 ACCs in TCGA were obtained from GEPIA.
Weiwei Liang, Fangfang Sun
doaj   +1 more source

Comprehensive analysis of competitive endogenous RNA associated with immune infiltration in lung adenocarcinoma

Scientific Reports, 2021
To identify the prognostic biomarker of the competitive endogenous RNA (ceRNA) and explore the tumor infiltrating immune cells (TIICs) which might be the potential prognostic factors in lung adenocarcinoma.
Wenjie Chen, Wen Li, Zhenkun Liu, Guangzhi Ma, Yunfu Deng, Xiaogang Li, Zhu Wang, Qinghua zhou   +7 more
doaj   +1 more source

Comprehensive analysis of cuproptosis-related ceRNA network and immune infiltration in diabetic kidney disease. [PDF]

Heliyon
Lan F, Zhao J, Liang D, Mo C, Shi W.
europepmc   +3 more sources

STARD13-correlated ceRNA network-directed inhibition on YAP/TAZ activity suppresses stemness of breast cancer via co-regulating Hippo and Rho-GTPase/F-actin signaling

Journal of Hematology & Oncology, 2018
Background Targeting cancer stem cells is critical for suppressing cancer progression and recurrence. Finding novel markers or related pathways could help eradicate or diagnose cancer in clinic.
Lufeng Zheng, Chenxi Xiang, Xiaoman Li, Qianqian Guo, Lanlan Gao, Haiwei Ni, Yufeng Xia, Tao Xi   +7 more
doaj   +1 more source

ceRNAshiny: An Interactive R/Shiny App for Identification and Analysis of ceRNA Regulation

Frontiers in Molecular Biosciences, 2022
The competing endogenous RNA (ceRNA) network is a newly discovered post-transcriptional regulation that controls both physiological and pathological progresses. Increasing research studies have been pivoted on this theory to explore the function of novel
Yueqiang Song, Jia Li, Yiming Mao, Xi Zhang, Xi Zhang   +4 more
doaj   +1 more source

Development of an Inflammation-Related lncRNA-miRNA-mRNA Network Based on Competing Endogenous RNA in Breast Cancer at Single-Cell Resolution

Frontiers in Cell and Developmental Biology, 2022
The role and mechanism of inflammation in breast cancer is unclear. This study aims to probe the relationship between inflammation and long non-coding RNAs (lncRNAs) and to stablish an inflammation-related competing endogenous RNA (ceRNA) network in ...
Jingxing Liu, Shuyuan Xiao, Jing Chen
doaj   +1 more source