Results 31 to 40 of about 6,111,011 (310)
Autophagy-Related Genes Predict the Progression of Periodontitis Through the ceRNA Network
Journal of Inflammation Research, 2022 Purpose The goal of this study was to identify the crucial autophagy-related genes (ARGs) in periodontitis and construct mRNA-miRNA-lncRNA networks to further understand the pathogenesis of periodontitis. Methods We used the Gene Expression Omnibus (GEO)
Mengyao Bian +5 more
semanticscholar +1 more source
Identification and functional analysis of a three-miRNA ceRNA network in hypertrophic scars
Journal of Translational Medicine, 2021 Background Hypertrophic scar (HTS) is a fibrotic disorder of skins and may have repercussions on the appearance as well as functions of patients. Recent studies related have shown that competitive endogenous RNA (ceRNA) networks centering around miRNAs ...
Zewei Zhang +10 more
doaj +1 more source
Frontiers in Immunology, 2022 Background Ulcerative colitis (UC) is an inflammatory disease of the intestinal mucosa, and its incidence is steadily increasing worldwide. Intestinal immune dysfunction has been identified as a central event in UC pathogenesis.
Mengmeng Xu +11 more
semanticscholar +1 more source
Interactions between Distant ceRNAs in Regulatory Networks [PDF]
Biophysical Journal, 2014 Competing endogenous RNAs (ceRNAs) were recently introduced as RNA transcripts that affect each other's expression level through competition for their microRNA (miRNA) coregulators. This stems from the bidirectional effects between miRNAs and their target RNAs, where a change in the expression level of one target affects the level of the miRNA ...
Mor Nitzan +4 more
openaire +4 more sources
ceRNAs in Cancer: Mechanism and Functions in a Comprehensive Regulatory Network [PDF]
Journal of Oncology, 2021 Noncoding RNAs have been shown with powerful ability in post-transcriptional regulation, enabling intertwined RNA crosstalk and global molecular interaction in a large amount of dysfunctional conditions including cancer. Competing endogenous RNAs (ceRNAs) are those competitively binding with shared microRNAs (miRNAs), freeing their counterparts from ...
Ni Yang +3 more
openaire +2 more sources
Identification of lncRNA/circRNA-miRNA-mRNA ceRNA Network as Biomarkers for Hepatocellular Carcinoma
Frontiers in Genetics, 2022 Background: Hepatocellular carcinoma (HCC) accounts for the majority of liver cancer, with the incidence and mortality rates increasing every year. Despite the improvement of clinical management, substantial challenges remain due to its high recurrence ...
Shanshan Chen +3 more
semanticscholar +1 more source
Construction of a ceRNA Network Related to Rheumatoid Arthritis
Genes, 2022 (1) Background: Rheumatoid arthritis (RA) is a common systemic autoimmune disease affecting many people and has an unclear and complicated physiological mechanism. The competing endogenous RNA (ceRNA) network plays an essential role in the development and occurrence of various human physiological processes. This study aimed to construct a ceRNA network
Huang, Zhanya, Kuang, Nanzhen
openaire +2 more sources
Heliyon, 2023 Accumulating evidence showed that competing endogenous RNA (ceRNA) mechanism plays a pivotal role in salt sensitivity of blood pressure (SSBP). We constructed a ceRNA network based on SSBP-related differently expressed lncRNAs (2), mRNAs (73) and miRNAs (
Wenjuan Peng +8 more
doaj +1 more source
Mathematical Biosciences and Engineering, 2021 Heart failure (HF), a common disease in adults, accounts for significantly global morbidity and mortality. Due to population aging, therapeutic progression in acute cardiovascular events, the prevalence of HF is increasing, in spite of the efficacy of ...
Xudan Ma +5 more
doaj +1 more source
Journal of Immunological Research, 2022 Background. Myocardial ischemia/reperfusion (MI/R) injury is a common pathology in ischemia heart disease. Long noncoding RNAs (lncRNAs) are significant regulators related to many ischemia/reperfusion conditions.
Ying Han +6 more
semanticscholar +1 more source