Results 41 to 50 of about 17,535 (240)
Heliyon, 2022 Background: Hepatitis C virus (HCV) infection contribute to liver fibrosis and cirrhosis, which significantly increases the risk of hepatocellular carcinoma (HCC) development.
Lishi Shao +3 more
doaj +1 more source
Comprehensive analysis of ceRNA network of ERCC4 in colorectal cancer
PeerJ, 2021 Objective ERCC4 is one of the most significant molecules of Nucleotide Excision Repair (NER), which has been researched due to its high expression in colorectal cancer (CRC). This study aimed to find out the ceRNA (competitive endogenous RNA) network of ERCC4 in CRC.
Huixin Hu +5 more
openaire +3 more sources
Systematic Identification of lncRNA-Associated ceRNA Networks in Immune Thrombocytopenia [PDF]
Computational and Mathematical Methods in Medicine, 2020 Primary immune thrombocytopenia (ITP) is an autoimmune disease. However, the molecular mechanisms underlying ITP remained to be further investigated. In the present study, we analyzed a series of public datasets (including GSE43177 and GSE43178) and identified 468 upregulated mRNAs, 272 downregulated mRNAs, 134 upregulated lncRNAs, 23 downregulated ...
Zhenwei Fan +6 more
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Frontiers in Cardiovascular Medicine, 2022 BackgroundAccumulated studies have revealed that long non-coding RNAs (lncRNAs) play critical roles in human diseases by acting as competing endogenous RNAs (ceRNAs).
Xiangyu Ke +8 more
doaj +1 more source
ceRNA network analysis reveals prognostic markers for glioblastoma
Oncology Letters, 2019 Glioblastoma (GBM) is a common aggressive cancer that originates in the brain, which has a poor prognosis. It is therefore crucial to understand its underlying genetic mechanisms in order to develop novel therapies. The present study aimed to identify some prognostic markers and candidate therapeutic targets for GBM.
Wang, Hao +3 more
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Cupid: simultaneous reconstruction of microRNA-target and ceRNA networks [PDF]
Genome Research, 2014 We introduce a method for simultaneous prediction of microRNA–target interactions and their mediated competitive endogenous RNA (ceRNA) interactions. Using high-throughput validation assays in breast cancer cell lines, we show that our integrative approach significantly improves on microRNA–target prediction accuracy as assessed by both mRNA and ...
Chiu HS +16 more
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Substrate‐Selective Temperature‐Controlled Synthesis of Thiophene Derivatives at Interfaces
Angewandte Chemie, EarlyView.The deposition of a dithiophene derivative on Ag(111) at room temperature followed by annealing gives rise to molecular wires, whereas the adsorption of the same precursor on a hot substrate affords the formation of benzotrithiophene species. Abstract The temperature‐controlled transformation of organic molecules at interfaces is an incipient yet ...
Elena Pérez‐Elvira +16 more
wiley +2 more sources
Frontiers in Genetics, 2022 Background: Numerous studies have suggested that programmed cell death (PCD) pathways play vital roles in cerebral ischemia/reperfusion (I/R) injury.
Jun Shu, Lu Yang, Wenshi Wei, Li Zhang
doaj +1 more source
HumanViCe: host ceRNA network in virus infected cells in human [PDF]
Frontiers in Genetics, 2014 Host-virus interaction via host cellular components has been an important field of research in recent times. RNA interference mediated by short interfering RNAs and microRNAs (miRNA), is a widespread anti-viral defense strategy. Importantly, viruses also encode their own miRNAs.
Suman eGhosal +4 more
openaire +3 more sources
Identification of Long Noncoding RNA Associated ceRNA Networks in Rosacea [PDF]
BioMed Research International, 2020 Rosacea is a chronic and relapsing inflammatory cutaneous disorder with highly variable prevalence worldwide that adversely affects the health of patients and their quality of life. However, the molecular characterization of each rosacea subtype is still unclear.
Lian Wang +8 more
openaire +2 more sources