Results 41 to 50 of about 6,111,011 (310)

A New Strategy to Identify ceRNA-Based CCDC144NL-AS1/SERPINE1 Regulatory Axis as a Novel Prognostic Biomarker for Stomach Adenocarcinoma via High Throughput Transcriptome Data Mining and Computational Verification

open access: yesFrontiers in Oncology, 2022
Stomach adenocarcinoma (STAD) is one of the most malignant cancers that endanger human health. There is growing evidence that competitive endogenous RNA (ceRNA) regulatory networks play an important role in various human tumors.
Zhihong Huang   +12 more
doaj   +1 more source

A Novel Immune-Related ceRNA Network and Relative Potential Therapeutic Drug Prediction in ccRCC

open access: yesFrontiers in Genetics, 2022
Renal cell carcinoma (RCC) is the third common solid tumor in the urinary system with a high distant metastasis rate. The five-year survival rate of RCC has reached 75%, benefiting from the emergence and update of multiple treatments, while its ...
Weiquan Li   +4 more
semanticscholar   +1 more source

Identifying a Comprehensive ceRNA Network to Reveal Novel Targets for the Pathogenesis of Parkinson's Disease

open access: yesFrontiers in Neurology, 2020
Parkinson's disease (PD) is the second commonest progressive neurodegenerative disease worldwide. Increasing evidence reveals that non-coding RNAs play roles in the pathophysiological process of PD.
Xi Zhang   +8 more
doaj   +1 more source

Integrated Analysis of circRNA-miRNA-mRNA ceRNA Network in Cardiac Hypertrophy

open access: yesFrontiers in Genetics, 2022
Cardiac hypertrophy is an adaptive cardiac response that accommodates the variable hemodynamic demands of the human body during extended periods of preload or afterload increase.
Yangfeng Chen   +7 more
semanticscholar   +1 more source

Comprehensive analysis of ceRNA network of ERCC4 in colorectal cancer

open access: yesPeerJ, 2021
Objective ERCC4 is one of the most significant molecules of Nucleotide Excision Repair (NER), which has been researched due to its high expression in colorectal cancer (CRC). This study aimed to find out the ceRNA (competitive endogenous RNA) network of ERCC4 in CRC.
Huixin Hu   +5 more
openaire   +3 more sources

Comprehensive analysis of the ceRNA network in coronary artery disease [PDF]

open access: yesScientific Reports, 2021
AbstractWith the rapid aging of the population, coronary artery disease (CAD) has become one of the most fatal chronic diseases. However, the genetic mechanism of CAD is still unclear. The purpose of this study is to construct the lncRNA-miRNA-mRNA regulatory network for CAD diseases and systematically identify differentially expressed genes in ...
Weikang Bian   +8 more
openaire   +3 more sources

Identification of functional lncRNAs through constructing a lncRNA-associated ceRNA network in myocardial infarction

open access: yesMathematical Biosciences and Engineering, 2021
Myocardial infarction (MI) is a type of coronary heart disease, which refers to the ischemic necrosis of the heart muscle. A large number of studies have discussed the mechanism of MI from the perspective of competing endogenous RNA (ceRNA) network ...
Beibei Zhu, Yue Mao, Mei Li
doaj   +1 more source

Comprehensive analysis of dysregulated circular RNAs and construction of a ceRNA network involved in the pathology of Alzheimer’s disease in a 5 × FAD mouse model

open access: yesFrontiers in Aging Neuroscience, 2022
Introduction Alzheimer’s disease (AD) causes a decline in cognitive function that poses a significant hazard to human health. However, the exact pathogenesis of AD and effective treatment have both proven elusive.
Ting Sun   +5 more
semanticscholar   +1 more source

Analyzing the lncRNA, miRNA, and mRNA-associated ceRNA networks to reveal potential prognostic biomarkers for glioblastoma multiforme

open access: yesCancer Cell International, 2020
Background Glioblastoma multiforme (GBM) is the most seriously brain tumor with extremely poor prognosis. Recent research has demonstrated that competitive endogenous RNA (ceRNA) network which long noncoding RNAs (lncRNAs) act as microRNA (miRNA) sponges
Xiaolong Zhu   +5 more
doaj   +1 more source

ceRNAshiny: An Interactive R/Shiny App for Identification and Analysis of ceRNA Regulation

open access: yesFrontiers in Molecular Biosciences, 2022
The competing endogenous RNA (ceRNA) network is a newly discovered post-transcriptional regulation that controls both physiological and pathological progresses. Increasing research studies have been pivoted on this theory to explore the function of novel
Yueqiang Song   +4 more
doaj   +1 more source

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