Results 51 to 60 of about 6,111,011 (310)
Dysfunction and ceRNA network of the tumor suppressor miR-637 in cancer development and prognosis
Biomarker Research, 2022 MicroRNAs (miRNAs) are a class of small non-coding RNAs ranging from 17 to 25 nt in length. miR-637 is down-regulated in most cancers and up-regulated only in clear cell renal cell carcinoma (ccRCC).
Jinze Shen +7 more
semanticscholar +1 more source
Competing Endogenous RNA Network Analysis Reveals Pivotal ceRNAs in Adrenocortical Carcinoma
Frontiers in Endocrinology, 2019 Objective: To construct ceRNA network and identify pivotal competing endogenous RNAs (ceRNAs) in adrenocortical carcinoma (ACC) using ceRNA network analysis.Methods: The RNA sequencing expression data of 77 ACCs in TCGA were obtained from GEPIA.
Weiwei Liang, Fangfang Sun
doaj +1 more source
Scientific Reports, 2021 To identify the prognostic biomarker of the competitive endogenous RNA (ceRNA) and explore the tumor infiltrating immune cells (TIICs) which might be the potential prognostic factors in lung adenocarcinoma.
Wenjie Chen +7 more
doaj +1 more source
A Potential ceRNA Network for Neurological Damage in Preterm Infants
BioMed Research International, 2021 Objective. This study is aimed at identifying key genes involved in neurological damage in preterm infants and at determining their potential circRNA‐miRNA‐mRNA regulatory mechanisms. Methods. Differentially expressed miRNAs, mRNAs, and circRNAs were downloaded from the GEO database.
Jin Huang, Xuejing Liang, Zhenyu Cai
openaire +3 more sources
Probing the limits to microRNA-mediated control of gene expression [PDF]
, 2016 According to the `ceRNA hypothesis', microRNAs (miRNAs) may act as mediators of an effective positive interaction between long coding or non-coding RNA molecules, carrying significant potential implications for a variety of biological processes.
De Martino, Andrea +3 more
core +6 more sources
Regulation of Long Non-coding RNA KCNQ1OT1 Network in Colorectal Cancer Immunity
Frontiers in Genetics, 2021 Over the past few decades, researchers have become aware of the importance of non-coding RNA, which makes up the vast majority of the transcriptome.
Junjie Liu +3 more
doaj +1 more source
PseudoFuN: Deriving functional potentials of pseudogenes from integrative relationships with genes and microRNAs across 32 cancers [PDF]
, 2019 BACKGROUND: Long thought "relics" of evolution, not until recently have pseudogenes been of medical interest regarding regulation in cancer. Often, these regulatory roles are a direct by-product of their close sequence homology to protein-coding genes.
Campbell, Moray J. +7 more
core +1 more source
Frontiers in Cellular and Infection Microbiology, 2022 Hepatitis B virus (HBV) infection is a main carcinogenic factor of hepatocellular carcinoma (HCC). TPX2 microtubule nucleation factor is recently recommended as a novel prognostic biomarker in HBV-infected HCC tissues.
Gaopeng Li +13 more
semanticscholar +1 more source
BMC Medical Genomics, 2022 Research Highlights It was the first time to explore the disorder of ceRNA network involved in the pathogenesis of AIH. The co-expression relationship between the differentially expressed lncRNAs, miRNAs and mRNAs were predicted. The potential biological
Zhencheng Li +6 more
doaj +1 more source
Frontiers in Genetics, 2021 ObjectiveAcute lymphoblastic leukemia (ALL) is a malignant disease most commonly diagnosed in adolescents and young adults. This study aimed to explore potential signatures and their functions for ALL.MethodsDifferentially expressed mRNAs (DEmRNAs) and ...
Weimin Wang +6 more
doaj +1 more source