Results 61 to 70 of about 6,111,011 (310)
The miR-223 host non-coding transcript linc-223 induces IRF4 expression in acute myeloid leukemia by acting as a competing endogenous RNA [PDF]
, 2016 Alterations in genetic programs required for terminal myeloid differentiation and aberrant proliferation characterize acute myeloid leukemia (AML) cells.
Bozzoni, Irene +8 more
core +2 more sources
Construction of a four-mRNA prognostic signature with its ceRNA network in CESC
Scientific Reports, 2022 Cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC) tumorigenesis involves a combination of multiple genetic alteration processes.
Lang Li +5 more
semanticscholar +1 more source
Frontiers in Cell and Developmental Biology, 2022 The role and mechanism of inflammation in breast cancer is unclear. This study aims to probe the relationship between inflammation and long non-coding RNAs (lncRNAs) and to stablish an inflammation-related competing endogenous RNA (ceRNA) network in ...
Jingxing Liu, Shuyuan Xiao, Jing Chen
doaj +1 more source
Journal of Inflammation Research, 2022 Background and Purpose Accumulating evidence suggests that circular RNAs (circRNAs) are involved in immune and inflammatory processes after acute ischemic stroke (AIS). However, the roles of circRNA-mediated competing endogenous RNA (ceRNA) in modulating
Xing Wang +4 more
semanticscholar +1 more source
Extensive ceRNA–ceRNA interaction networks mediated by miRNAs regulate development in multiple rhesus tissues [PDF]
Nucleic Acids Research, 2016 Crosstalk between RNAs mediated by shared microRNAs (miRNAs) represents a novel layer of gene regulation, which plays important roles in development. In this study, we analyzed time series expression data for coding genes and long non-coding RNAs (lncRNAs) to identify thousands of interactions among competitive endogenous RNAs (ceRNAs) in four rhesus ...
Zujing Han +15 more
openaire +2 more sources
A ceRNA network mediated by LINC00475 in papillary thyroid carcinoma
Open Medicine, 2021 Abstract Papillary thyroid carcinoma (PTC) is the most frequent histological type of differentiated thyroid carcinoma. Long noncoding RNAs (lncRNAs) have been widely reported to play a key role in human malignancies, and PTC is included. This study aimed to find out the functions and mechanism of lncRNA LINC00475 in PTC.
Yang Yarong +5 more
openaire +3 more sources
Construction of a ceRNA network in polycystic ovary syndrome (PCOS) driven by exosomal lncRNA
Frontiers in Genetics, 2022 Polycystic ovary syndrome (PCOS), a common and frustrating syndrome in women of reproductive age, is characterized by symptoms including hyperandrogenemia, ovulation dysfunction, and polycystic ovaries.
L. Bai +5 more
semanticscholar +1 more source
Integrative Clustering Reveals a Novel Subtype of Soft Tissue Sarcoma With Poor Prognosis
Frontiers in Genetics, 2020 BackgroundSoft tissue sarcomas (STSs) are heterogeneous at the clinical and molecular level and need to be further sub-clustered for treatment and prognosis.Materials And MethodsSTSs were sub-clustered based on RNAseq and miRNAseq data extracted from The
Zhenhua Zhu +4 more
doaj +1 more source
Pathology and Oncology Research, 2022 Background: Colorectal cancer (CRC) is currently the fourth most common cancer worldwide. The roles of exosomal competing endogenous RNAs (ceRNAs) in CRC remain unclear.
Yajing Zhao +3 more
semanticscholar +1 more source
High-throughput validation of ceRNA regulatory networks
BMC Genomics, 2017 Background: MicroRNAs (miRNAs) play multiple roles in tumor biology [1]. Interestingly, reports from multiple groups suggest that miRNA targets may be coupled through competitive stoichiometric sequestration [2]. Specifically, computational models predicted [3, 4] and experimental assays confirmed [5, 6] that miRNA activity is dependent on miRNA target
Andrea Califano +9 more
openaire +5 more sources