Results 71 to 80 of about 17,535 (240)

Comprehensive characterization of the competitive endogenous RNA network revealing its immune-related functions in hepatic ischemia-reperfusion injury.

PLoS ONE
Hepatic ischemia-reperfusion injury (HIRI) is a common complication in liver surgery and transplantation. Recent studies have revealed the significant role of the competing endogenous RNA (ceRNA) network in HIRI.
Lirong Liu, Qi Wang, Shuang Qin, Chang Su, Xin Hai, Zhenkuan Yuan   +5 more
doaj   +1 more source

Identification of CeRNA Regulatory Networks in Atrial Fibrillation Using Nanodelivery

Evidence-Based Complementary and Alternative Medicine, 2022
The initiation and maintenance of AF is a complex biological process that is the ultimate manifestation of many cardiovascular diseases. And the pathogenesis of atrial fibrillation (AF) is unclear. Therefore, this study aimed to find the potential competing endogenous RNAs (ceRNAs) network and molecular dysregulation mechanism associated with AF ...
Ping Lin, Lingqiang Meng, Lei Lyu
openaire   +2 more sources

Identification and validation of a novel glycolysis-related ceRNA network for sepsis-induced cardiomyopathy

Frontiers in Medicine
PurposeSepsis-induced cardiomyopathy (SIC) is a major life-threatening condition in critically infected patients. Early diagnosis and intervention are important to improve patient prognosis.
Lulu Cheng, Lulu Cheng, Jiabin Liang, Fangmei Xie, Zeping Han, Wenfeng Luo, Hanwei Chen, Jinhua He   +7 more
doaj   +1 more source

Comprehensive analysis of the FOXA1-related ceRNA network and identification of the MAGI2-AS3/DUSP2 axis as a prognostic biomarker in prostate cancer

Frontiers in Oncology, 2023
BackgroundProstate cancer (PCa) is the second most common cause of cancer-related deaths in American men. Even though increasing evidence has disclosed the competitive endogenous RNA (ceRNA) regulatory networks among cancers, the complexity and behavior ...
Guo Yang, Xiong Chen, Zhen Quan, Miao Liu, Yuan Guo, Yangbin Tang, Lang Peng, Leilei Wang, Yingying Wu, Xiaohou Wu, Jiayu Liu, Yongbo Zheng   +11 more
doaj   +1 more source

Comprehensive analysis of ceRNA network related to lincRNA in glioblastoma and prediction of clinical prognosis

BMC Cancer, 2021
Background Long intergenic non-coding RNAs (lincRNAs) are capable of regulating several tumours, while competitive endogenous RNA (ceRNA) networks are of great significance in revealing the biological mechanism of tumours.
Guangdong Liu, Danian Liu, Jingjing Huang, Jianxin Li, Chuang Wang, Guangyao Liu, Shiqiang Ge, Haidong Gong   +7 more
doaj   +1 more source

LncRSFD Alternative Splicing Modulates the Proliferation and Differentiation of Adipocytes Through Sponging miRNAs

Animal Research and One Health, EarlyView.
This study identified a molecule named lncRSFD, which is highly expressed in sheep adipose tissues. The lncRSFD gene generates two distinct transcript variants via alternative splicing: lncRSFD‐L and lncRSFD‐S. Functionally, lncRSFD alternative splicing (lncRSFD‐L/S) promotes the proliferation, differentiation, and lipid metabolism of adipocytes ...
Jinpeng Wang, Qiuyang Li, Zhiying Wang, Shan Zhang, Kassahun Bekana, Qingfeng Zhang, Juanshan Zheng, Hongwei Xu, Xianyong Lan, Chuanying Pan   +9 more
wiley   +1 more source

Study of Neuronal Apoptosis ceRNA Network in Hippocampal Sclerosis of Human Temporal Lobe Epilepsy by RNA-Seq

Frontiers in Neuroscience, 2021
Hippocampal sclerosis (HS) is one of the most common pathological type of intractable temporal lobe epilepsy (TLE), often characterized by hippocampal atrophy, neuronal apoptosis, and gliogenesis.
Shengkun Yu, Yifei Gu, Tianyu Wang, Long Mu, Haiyang Wang, Shi Yan, Aoweng Wang, Jiabin Wang, Li Liu, Hong Shen, Meng Na, Zhiguo Lin   +11 more
doaj   +1 more source

Self‐assembly and Lateral Cobalt Coordination of a Fivefold Symmetric Cyanostar Macrocycle on an Au(111) Surface

Chemistry – A European Journal, EarlyView.
Herein, we report the first example of the formation of a close‐packed, regular 2D monolayer of a fivefold symmetric cyanostar macrocycle on an Au(111) surface under ultra‐high vacuum and the structural modification of such self‐assembled architecture upon cobalt atom deposition.
Lenka Černá, Miguel Martínez García, Shanmugasibi K. Mathialagan, Sofía O. Parreiras, Koen Lauwaet, José Ignacio Urgel, Aurelio Gallardo, Amar H. Flood, Tomás Torres, José M. Gallego, Giovanni Bottari, David Écija   +11 more
wiley   +1 more source

TET3‐Mediated m5C Modification of CCAT2 Accelerates Cardiac Microvascular Endothelial Cell Damage in Acute Coronary Syndrome

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Acute coronary syndrome (ACS) is a clinical syndrome involving myocardial ischemia. This study aimed to elucidate the mechanism of TET3 in ACS‐induced CMEC damage, thereby identifying a new target for ACS treatment. The expression of TET3 in ACS patients and healthy subjects was analyzed.
Jun‐Cheng Liu, Wen‐Juan Wang, Ting‐Ting Zhang, Qi‐Chong Yang, Haliminai Dilimulati, Song‐Tao An   +5 more
wiley   +1 more source

The regulatory mechanism of LncRNA-mediated ceRNA network in osteosarcoma

Scientific Reports, 2022
AbstractAberrantly expressed lncRNAs have been reported to be closely related to the oncogenesis and development of osteosarcoma. However, the role of a dysregulated lncRNA-miRNA-mRNA network in osteosarcoma in the same individual needs to be further investigated. Whole transcriptome sequencing was performed on the tumour tissues and matched paratumour
Chengsen Lin, Jifeng Miao, Juliang He, Wenyu Feng, Xianxiang Chen, Xiaohong Jiang, Jianhong Liu, Boxiang Li, Qian Huang, Shijie Liao, Yun Liu   +10 more
openaire   +3 more sources