Results 111 to 120 of about 1,781 (177)

Inactivation of ceramide synthase 6 in mice results in an altered sphingolipid metabolism and behavioral abnormalities

, 2013
The N-acyl chain length of ceramides is determined by the specificity of different ceramide synthases (CerS). The CerS family in mammals consists of six members with different substrate specificities and expression patterns.
Dere, E., Willecke, K., Zlomuzica, A., Ebel, P., Degen, J., Mariani, J., Ginkel, C., Minich, D., Petrasch-Parwez, E., Eckhardt, M., Vom Dorp, K., Doermann, P., Kinugawa, K., Welcker, J.   +13 more
core   +1 more source

MYC-activated CERS6-AS1 sponges miR-6838-5p and regulates the expression of RUBCNL in colorectal cancer

Cellular and Molecular Biology, 2022
Dong, Chen, Huiming, You, Xiaoping, Xu, Daocheng, Liu, Minmin, Shen, Yuan, Pan, Zhaohui, Liu, Lei, Zhang, Huijuan, Wang   +8 more
openaire   +2 more sources

Role of ceramide synthase-6 overexpression in chemoresistance in T-cell acute lymphoblastic leukemia

, 2018
Ceramide synthases (CERS) produce ceramides which are key intermediators in the biosynthesis of complex sphingolipids and play an important role in cell proliferation, differentiation, apoptosis and senescence.
Verlekar, Dattesh
core  

Sphingolipid Metabolism in Obesity: Bidirectional Regulation and Comparative Perspectives on Plant Sphingolipids. [PDF]

Nutrients
Li M, Yao Y, Li T, Cai T, Zhao F, Fang Y, Zheng Y, Fei C, Yang C, Sun W, Shao M, Li L, Zheng Y.   +12 more
europepmc   +1 more source

Sphingolipid Metabolism in Oral Diseases: Pathogenic Mechanisms, Biomarkers, and Therapeutic Opportunities. [PDF]

Biomedicines
Zang S, Huang J, Duan N, Wang W, Wang X, Peng Q, Han W.   +6 more
europepmc   +1 more source

Sphingolipid metabolism and hematologic disorders: current understanding and future directions. [PDF]

Front Physiol
Kuang Z, Huang T, Chen G.
europepmc   +1 more source

Response of Liver Metabolome to Dietary Folic Acid Alterations in WT and CerS6 Knockout Mice (P08-095-19) [PDF]

Current Developments in Nutrition, 2019
Keri Barron, Natalia Krupenko
openaire   +1 more source

Lipid metabolism drives podocyte injury in diabetic kidney disease. [PDF]

Front Immunol
Shang J, Zeng Z, Chai S, Lv X, Han X, Ma B, Xu Y, Wang R, Lv Z.   +8 more
europepmc   +1 more source

Intestinal fungi shape the biology of the mammalian gut. [PDF]

PLoS Pathog
Lindemann-Pérez E, Pérez JC.
europepmc   +1 more source

Diet-Induced Ceramide Remodeling as a Mechanistic Link to Cardiac Metabolic Dysfunction. [PDF]

Nutrients
Basilicata MG, Scisciola L, Capone F, Trevellin E, Paolisso P, Belmonte M, Marfella LV, Zanzillo M, Sabbatino L, De Rosa L, Celardo N, Acunto M, Pesapane A, Fontanella RA, Balzano N, Lettera N, Palazzo AMM, Tortorella G, Joshi R, Zia A, Ulfat Z, Arshad M, Fioretto P, Paolisso G, Barbieri M.   +24 more
europepmc   +1 more source