Results 161 to 170 of about 1,781 (177)

LncRNA CERS6-AS1 Is a Tumor Promoter in Cervical Cancer by Sponging miR-195-5p.

Annals of clinical and laboratory science, 2023
CERS6 antisense RNA 1 (CERS6-AS1), a long non-coding RNA (lncRNA), plays a role in the malignant progression of a variety of cancers. However, it is unclear whether it affects the malignant behavior of cervical cancer (CC) cells.CERS6-AS1 and miR-195-5p expression was estimated in CC via qRT-PCR. CCK-8, caspase-3 activity, scratch, and Transwell assays
Shiyi, Xiong, Han, Song
openaire   +1 more source

LncRNA CERS6 - AS1 mediates the IGF2BP1/LIN28B axis to promote proliferation, migration and invasion in ovarian cancer

Biochimica Et Biophysica Acta - Proteins and Proteomics
Ovarian cancer remains a significant clinical challenge for women's health, making it imperative to elucidate its underlying molecular mechanisms. LncRNA CERS6-AS1 and LIN28B-binding proteins play a vital role in the development of ovarian cancer. The expression levels of CERS6-AS1 and LIN28B in ovarian cancer tissues and cell lines were evaluated ...
Chengzhen Gao
exaly   +3 more sources

A symbiotic filamentous gut fungus ameliorates MASH via a secondary metabolite–CerS6–ceramide axis

Science
The gut microbiota is known to be associated with a variety of human metabolic diseases, including metabolic dysfunction–associated steatohepatitis (MASH). Fungi are increasingly recognized as important members of this community; however, the role of fungal symbionts in metabolic diseases is unknown.
Shuang Zhou, Meng Li, Pengcheng Wang, Chenghao Guo, Jinxin Zhang, Xi Luo, Yu-Chen Fan, En-Qiang Chen, Xingshun Qi, Jinjun Chen, Lechi Ye, Hai-Yang Yuan, Wen-Bing Yin, Kai Wang, Ming-Hua Zheng, Yanli Pang, Jie Qiao, Changtao Jiang   +17 more
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Targeting CERS6-AS1/FGFR1 axis as synthetic vulnerability to constrain stromal cells supported proliferation in Mantle cell lymphoma

Leukemia
The interaction between stromal and tumor cells in tumor microenvironment is a crucial factor in Mantle cell lymphoma (MCL) progression and therapy resistance. We have identified a long non-coding RNA, CERS6-AS1, upregulated in MCL and associated with poor overall survival.
Udita Jindal, Mukesh Mamgain, Uttam Kumar Nath, Isha Sharma, Bhaskar Pant, Ankita Sharma, Archita Gupta, Khaliqur Rahman, Sunil Yadav, Manish Pratap Singh, Shaktiprasad Mishra, Chandra Praksah Chaturvedi, Jose Courty, Navin Singh, Seema Gupta, Sanjeev Kumar, Shailendra Prasad Verma, Saumyaranjan Mallick, Ajay Gogia, Sunil Raghav, Jayanta Sarkar, Kinshuk Raj Srivastava, Dipak Datta, Neeraj Jain   +23 more
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Bioengineered

Bioengineered, 2021
Nan Luo, Yubin Hou, Zhengliang Li
exaly  

CERS6 antisense RNA 1 promotes colon cancer via upregulating mitochondrial calcium uniporter

European Journal of Clinical Investigation, 2023
Furang Wang
exaly  

Ceramide synthase 6 (CERS6; LASS6)

Science-Business eXchange, 2014
openaire   +1 more source

ANTISENSE OLIGONUCLEOTIDES TARGETING CERS6

2020
LINDHOLM MARIE WIRKSTRÖM, SCHMIDT STEFFEN   +1 more
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lncRNA CERS6-AS1 as ceRNA promote cell proliferation of breast cancer by sponging miR-125a-5p to upregulate BAP1 expression

Molecular Carcinogenesis, 2020
Yao Zhang, Liang Yan, Yuxin Jiang
exaly  

Multi-Omics Identifies CERS6 and C16:0 Ceramide in Podocytes as Novel Therapeutic Targets for Diabetic Kidney Disease

Journal of the American Society of Nephrology, 2021
Guanshi Zhang, Dusan Velickovic, Annapurna Pamreddy, Viji Nair, Blue Lake, Manjeri A. Venkatachalam, Matthias Kretzler, Christopher R. Anderton, Theodore Alexandrov, Kumar Sharma   +9 more
openaire   +1 more source