Integrative analysis of adenosine-related RNA modifications defines molecular subtypes of bladder cancer and identifies CES1 as a driver of tumor progression and immunotherapy resistance. [PDF]
Huo X +5 more
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Flumazenil reversal of remimazolam-induced sedation: a narrative review of safety, pharmacokinetics, and clinical considerations. [PDF]
Zhou Y +7 more
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Niraparib PBPK modeling to predict optimal dosage in patients with hepatic impairment. [PDF]
Pokladyuk A +4 more
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Pharmacogenomics of direct oral anticoagulants: a systematic review and meta-analysis. [PDF]
Chai H, Huo J, Chen H.
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Ester Prodrug NLRP3 Inflammasome Inhibitor NT-0796 is Brain Active due to Activation by Local Expression of Carboxylesterase-1. [PDF]
Digby Z +8 more
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Production of Novel Thermostable Esterases from <i>Thermus thermophilus</i> Strain ET-1 in <i>Escherichia coli</i> and <i>Thermus thermophilus</i> HB27 Using the Bifunctional Expression System pTGT-1 and Characterization of the Recombinant Enzymes. [PDF]
Valenzuela B +6 more
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Pharmacogenomic profiling of ABCB1 and CES1 in atrial fibrillation patients on dabigatran from a multiethnic Malaysian cohort. [PDF]
Tan SSN +10 more
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Experimental and In Silico Approaches to Study Carboxylesterase Substrate Specificity. [PDF]
Ribone SR, Quevedo MA.
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Dose Recommendation of Remimazolam Tosilate for General Anesthesia in Children and Adolescents: Synergistic Combination of PopPK and PBPK Approaches. [PDF]
Liang QY +4 more
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Network toxicology & molecular docking: endocrine-disrupting chemicals induce prostate cancer - a system study. [PDF]
Zhou Y +5 more
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